BONANNI, DAVIDE

BONANNI, DAVIDE  

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Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3 2019 Lolli, Marco L; Carnovale, Irene M; Pippione, Agnese C; Wahlgren, Weixiao Y; Bonanni, Davide; Marini, Elisabetta; Zonari, Daniele; Gallicchio, Margherita; Boscaro, Valentina; Goyal, Parveen; Friemann, Rosmarie; Rolando, Barbara; Bagnati, Renzo; Adinolfi, Salvatore; Oliaro-Bosso, Simonetta; Boschi, Donatella
Computational Method for Structure-Based Analysis of SAR Transfer 2020 Bonanni D.; Lolli M.L.; Bajorath J.
Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation 2018 Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli
A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors. 2019 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors 2019 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors able to restore in vitro and in vivo myeloid differentiation 2019 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo-keto reductase 1C3 target affinity 2019 Santos A.R.N.; Sheldrake H.M.; Ibrahim A.I.M.; Danta C.C.; Bonanni D.; Daga M.; Oliaro-Bosso S.; Boschi D.; Lolli M.L.; Pors K.
Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach 2017 Pippione, Agnese C.; Giraudo, Alessandro; Bonanni, Davide; Carnovale, Irene M.; Marini, Elisabetta; Cena, Clara; Costale, Annalisa; Zonari, Daniele; Pors, Klaus; Sadiq, Maria; Boschi, Donatella; Oliaro-Bosso, Simonetta; Lolli, Marco L
Improvement of in vivo pharmacokinetic profile of M433, a potent and innovative hDHODH inhibitor. 2019 Marta Alberti, Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Donatella Boschi, Marco Lucio Lolli
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase inhibitors 2018 Sainas S., Pippione A. C., Bonanni D., Giorgis Marta, Lupino E. , Circosta P. , Gaidano V. , Cignetti A. , Piccinini M. , Saglio G. , Al-Karadaghi S. , Boschi D., Lolli M.L.
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase (hDHODH) inhibitors 2018 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Giraudo Enrico, Goyal Parveen, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Friemann Rosmarie, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
Indomethacin Inhibits Proliferation In Cells Harbouring PIK3CA Mutations 2017 M. Gallicchio, M. Lolli, F. Spyrakis, D. Bonanni, V. Boscaro
New human dihydroorotate dehydrogenase inhibitors able to restore myeloid differentiation in AML 2018 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with hydroxypyrazole core: new scaffolds against malaria disease 2019 Pippione AC, Sainas S, Giraudo A, Bonanni D, Villella N, Bertea C, Friemann R, Al-Karadaghi S, Boschi D, Lolli ML.
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: Application of a bioisosteric scaffold hopping approach to flufenamic acid 2018 Pippione, Agnese Chiara; Carnovale, Irene Maria; Bonanni, Davide; Sini, Marcella; Goyal, Parveen; Marini, Elisabetta; Pors, Klaus; Adinolfi, Salvatore; Zonari, Daniele; Festuccia, Claudio; Wahlgren, Weixiao Yuan; Friemann, Rosmarie; Bagnati, Renzo; Boschi, Donatella; Oliaro-Bosso, Simonetta; Lolli, Marco Lucio
PROCEEDINGS OF THE MERCK & ELSEVIER YOUNG CHEMISTSSYMPOSIUM 2018 Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli
Synthesis, physiochemical proprieties and application of hydroxyazole systems as carboxylic acid isoster 2019 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Donatella Boschi, Marco L Lolli
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety 2021 Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L.
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors 2018 Sainas, Stefano; Pippione, Agnese C; Lupino, Elisa; Giorgis, Marta; Circosta, Paola; Gaidano, Valentina; Goyal, Parveen; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ducime, Alex; Andersson, Mikael; Järvå, Michael; Friemann, Rosmarie; Piccinini, Marco; Ramondetti, Cristina; Buccinnà, Barbara; Al-Karadaghi, Salam; Boschi, Donatella; Saglio, Giuseppe; Lolli, Marco L
Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors 2018 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Giraudo Enrico, Goyal Parveen, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Friemann Rosmarie, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio