Our findings indicate that ACEI may worsen OSA in subjects who develop upper airway irritation during treatment. In OSA, soft palate inflammation has been described as a consequence of snoring and of repeated closure/opening of the airway passages. The parallel decrease of eNO and AHI after ACEI withdrawal, suggests that cough and obstructive apnoeas were, at least in part, sustained by ACEI-induced upper airway inflammation. Our findings indicate that ACEI may increase the degree of OSA-induced inflammation and thus contribute to upper airway collapsibility during sleep
ACE-inhibitors and obstructive sleep apnoea
BUCCA, Caterina;BRUSSINO, Luisa;CICOLIN, Alessandro
2005-01-01
Abstract
Our findings indicate that ACEI may worsen OSA in subjects who develop upper airway irritation during treatment. In OSA, soft palate inflammation has been described as a consequence of snoring and of repeated closure/opening of the airway passages. The parallel decrease of eNO and AHI after ACEI withdrawal, suggests that cough and obstructive apnoeas were, at least in part, sustained by ACEI-induced upper airway inflammation. Our findings indicate that ACEI may increase the degree of OSA-induced inflammation and thus contribute to upper airway collapsibility during sleepFile in questo prodotto:
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