CINECA IRIS Institutional Research Information System

Radiomics features on CT scans to predict response to HER2-targeted therapy of hepatic metastases from colorectal cancer

Impact of network parameters on a U-Net based system for rectal cancer segmentation on MR images

The use of Deep Learning (DL) algorithms in the medical imaging field is increasing in recent years. However, they require the selection of a set of parameters to properly perform. In this study we evaluated the impact of three factors (the construction of the training set, the number of network layers and the loss function) on the performance of a U-Net system in the segmentation of Locally Advanced Rectal Cancer (LARC) on Magnetic Resonance Imaging (MRI). Images from 3 different institution...

A Deep Learning model to segment liver metastases on CT images acquired at different time-points during chemotherapy

The aim of this study is to present a fully automatic deep learning algorithm to segment liver Colorectal cancer metastases (lmCRC) on CT images, based on a U-Net structure, comparing nets with and without the transfer learning approach. This is a bi-centric study, enrolling patients who underwent CT exam before (baseline) and after first-line therapy (TP1). Patients were divided into training (using a portion of baseline sequences from both centers) to train the DL model, and two validation ...

Exploiting GPU computing for effective Agent-Based simulation: initial experiments

Agent-Based Modeling and Simulation (ABMS) has been increasingly applied in various research fields, thanks to the capability of these models to describe fine-grained realworld behavior and to the ease of interpretation by domain experts. However, such models lack a formal definition and well-defined semantics that are common to the different tools supporting ABMS. This may occasionally lead to greater complexity in interpreting the results with respect to other modeling approaches. To addres...