The present invention relates to Lanthanide (III) complex compounds that display at least two NMR-distinguishable steroisomers in solution and to the use thereof in CEST based MRI procedures as concentration independent responsive agents to provide in vivo determination of physical or chemical parameters of diagnostic interest.
CEST SYSTEMS EXHIBITING A CONCENTRATION INDEPENDENT RESPONSIVENESS
AIME, Silvio;DELLI CASTELLI, Daniela;TERRENO, Enzo;LONGO, DARIO LIVIO;
2010-01-01
Abstract
The present invention relates to Lanthanide (III) complex compounds that display at least two NMR-distinguishable steroisomers in solution and to the use thereof in CEST based MRI procedures as concentration independent responsive agents to provide in vivo determination of physical or chemical parameters of diagnostic interest.
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