Antifungal Susceptibility of Canine and Feline Malassezia spp. Isolates to Lactoferricin: Preliminary In-Vitro Study

Malassezia spp. is a fungus isolated from the skin and mucosae of dogs and cats, which may cause dermatitis and otitis. Therapies include the use of antibiotics, antifungals and glucocorticoids. Because of the antibiotic-resistance phenomenon, new alternative therapies are necessary. Bovine lactoferricin (Lfc) is a peptide derived from proteolytic cleavage of lactoferrin with proven antibacterial, antifungal and immunostimulatory activity. The aim of this study was to evaluate the antifungal susceptibility of Malassezia spp. to Lfc-Candioli Pharma (water solution 20%) using a microdilution method.