Erratum Following publication of the original article (Infez Med. volume 23, issue 4, pages 367-369, year 2015) we became aware of the following errors which we wish to correct. These corrections have no impact over the study results, their interpretation or conclusions. Title The correct title is the following: A probable drug-to-drug interaction between voriconazole and haloperidol in a CYP2C19 poor metabolizing patient Summary The correct summary is the following: SUMMARY We present a case of Aspergillus fumigatus renal abscess treated with voriconazole. Following haloperidol treatment we observed an unexpected increase in voriconazole - trough concentrations and liver function tests. CYP2C19*2 loss of function allele was stated and the introduction of haloperidol, a weak CYP3A4 inhibitor, probably explains this interaction.. Therapeutic drug monitoring and CYP2C19 genotyping may be suggested when administering voriconazole to complex patients.

Erratum: A probable drug-to-drug interaction between voriconazole and haloperidol in a slow metabolizer of CYP2C19 patient

MOTTA, ILARIA;CALCAGNO, Andrea;D'AVOLIO, ANTONIO;DE ROSA, Francesco Giuseppe;BONORA, Stefano
2016-01-01

Abstract

Erratum Following publication of the original article (Infez Med. volume 23, issue 4, pages 367-369, year 2015) we became aware of the following errors which we wish to correct. These corrections have no impact over the study results, their interpretation or conclusions. Title The correct title is the following: A probable drug-to-drug interaction between voriconazole and haloperidol in a CYP2C19 poor metabolizing patient Summary The correct summary is the following: SUMMARY We present a case of Aspergillus fumigatus renal abscess treated with voriconazole. Following haloperidol treatment we observed an unexpected increase in voriconazole - trough concentrations and liver function tests. CYP2C19*2 loss of function allele was stated and the introduction of haloperidol, a weak CYP3A4 inhibitor, probably explains this interaction.. Therapeutic drug monitoring and CYP2C19 genotyping may be suggested when administering voriconazole to complex patients.
2016
24
1
89
89
Motta, Ilaria; Calcagno, Andrea; Baietto, Lorena; D'Avolio, Antonio; De Rosa, Francesco Giuseppe; Bonora, Stefano
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1645514
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