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EnglishThe paper first reviews the main laser based cancer therapies and then presents a new 9xx nm high power laser diode system specifically devised to irradiate carbon graphitic nanoparticles that have shown photodynamic and photo-thermal behavior when exposed to near-IR laser light. The peculiarity of the laser system is that its delivery is through a fiber probe that integrates Bragg gratings to allow monitoring the induced temperature increase without introducing artifacts due to the interaction with the laser beam. Experimental validations through EPR spectrum and temperature measurements on hydroxylated fullerene and carbon nanoparticle samples are provided to assess the effectiveness of the developed system.
| Titolo: | A compact diode laser based all-fiber delivery system for PDT-FPTT with integrated temperature sensing capabilities |
| Autori Riconosciuti: | |
| Autori: | Riccardo Gassino , Ida Kokalari, Alberto Vallan , Ivana Fenoglio , Guido Perrone |
| Data di pubblicazione: | 2017 |
| Abstract: | The paper first reviews the main laser based cancer therapies and then presents a new 9xx nm high power laser diode system specifically devised to irradiate carbon graphitic nanoparticles that have shown photodynamic and photo-thermal behavior when exposed to near-IR laser light. The peculiarity of the laser system is that its delivery is through a fiber probe that integrates Bragg gratings to allow monitoring the induced temperature increase without introducing artifacts due to the interaction with the laser beam. Experimental validations through EPR spectrum and temperature measurements on hydroxylated fullerene and carbon nanoparticle samples are provided to assess the effectiveness of the developed system. |
| Editore: | SPIE-INT SOC OPTICAL ENGINEERING |
| Titolo del libro: | OPTICAL METHODS FOR TUMOR TREATMENT AND DETECTION: MECHANISMS AND TECHNIQUES IN PHOTODYNAMIC THERAPY XXVI |
| Volume: | 10047 |
| Pagina iniziale: | 1 |
| Pagina finale: | 1 |
| Nome del convegno: | Conference on Optical Methods for Tumor Treatment and Detection - Mechanisms and Techniques in Photodynamic Therapy XXVI |
| Luogo del convegno: | San Francisco, CA |
| Anno del convegno: | JANUARY 28-29, 2017 |
| Digital Object Identifier (DOI): | 10.1117/12.2254796 |
| ISBN: | 978-1-5106-0535-0 |
| Appare nelle tipologie: | 04A-Conference paper in volume |
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http://hdl.handle.net/2318/1667585
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