Vitamin D (VD) influences genetic expression through its receptor (VDR). VD pathway gene polymorphisms seem to influence antiviral drug pharmacokinetics and therapeutic outcome/toxicity. We investigated the association between daclatasvir (DCV) plasma concentrations and genetic variants (SNPs) associated with the VD pathway.

Vitamin D pathway gene polymorphisms affecting daclatasvir plasma concentration at 2 weeks and 1 month of therapy

Cusato, Jessica
Co-first
;
Nicolò, Amedeo De
Co-first
;
Boglione, Lucio;Favata, Fabio;Ariaudo, Alessandra;Pinna, Simone Mornese;Carcieri, Chiara;GUIDO, FEDERICA;Perri, Giovanni Di;D'Avolio, Antonio
Last
2018

Abstract

Vitamin D (VD) influences genetic expression through its receptor (VDR). VD pathway gene polymorphisms seem to influence antiviral drug pharmacokinetics and therapeutic outcome/toxicity. We investigated the association between daclatasvir (DCV) plasma concentrations and genetic variants (SNPs) associated with the VD pathway.
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706
CYP24A1; DAAs; SNP; VDR; pharmacogenetics; pharmacokinetics
Cusato, Jessica; Nicolò, Amedeo De; Boglione, Lucio; Favata, Fabio; Ariaudo, Alessandra; Pinna, Simone Mornese; Carcieri, Chiara; Guido, Federica; Cariti, Giuseppe; Perri, Giovanni Di; D'Avolio, Antonio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1678725
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