Mutations in the JAK2, CALR, and MPL genes have been shown to have prognostic value in essential thrombocythaemia (ET), but no clear association with morphological changes has been reported so far. We investigated the possible correlation between gene mutations and histopathological features in bone marrow (BM) biopsies of patients with ET.

JAK2V617F, CALR, and MPL Mutations and Bone Marrow Histology in Patients with Essential Thrombocythaemia

Pich, Achille;Riera, Ludovica;
2018-01-01

Abstract

Mutations in the JAK2, CALR, and MPL genes have been shown to have prognostic value in essential thrombocythaemia (ET), but no clear association with morphological changes has been reported so far. We investigated the possible correlation between gene mutations and histopathological features in bone marrow (BM) biopsies of patients with ET.
2018
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4
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https://www.karger.com/Article/FullText/493970
Bone marrow biopsy; CALR mutation; Essential thrombocythaemia; JAK2V617F mutation; MPL mutation
Pich, Achille; Riera, Ludovica; Francia di Celle, Paola; Beggiato, Eloise; Benevolo, Giulia; Godio, Laura
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1681164
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