The impact of the extraction technologies on product yield and analytical profile is relevant. This review is aiming to discuss recent experiences of successes and failures in non-conventional extraction scaling-up, to better understand the challenges and designing of existing and new techniques. Understanding the crucial extraction factors at laboratory and pilot scale is of paramount value for the engineering work of scaling-up. Besides, a careful analysis and modelling of heat and mass transfer and energy consumption, the design of industrial extraction plants driven by economic and environmental factors, are well covered in the present review. Current trend strongly favors scaling-up of green approaches that consumes less organic solvent(s), involves minimal operational steps, provides high throughput capability and assures highest yield at lower costs. Current and future challenges in scaling-up extraction of bioactive compounds require a parallel development of suitable analytical methods to monitor the process and ensure high yield and quality.

Recent advances in scaling-up of non-conventional extraction techniques: learning from successes and failures

Cravotto, G.;
2020-01-01

Abstract

The impact of the extraction technologies on product yield and analytical profile is relevant. This review is aiming to discuss recent experiences of successes and failures in non-conventional extraction scaling-up, to better understand the challenges and designing of existing and new techniques. Understanding the crucial extraction factors at laboratory and pilot scale is of paramount value for the engineering work of scaling-up. Besides, a careful analysis and modelling of heat and mass transfer and energy consumption, the design of industrial extraction plants driven by economic and environmental factors, are well covered in the present review. Current trend strongly favors scaling-up of green approaches that consumes less organic solvent(s), involves minimal operational steps, provides high throughput capability and assures highest yield at lower costs. Current and future challenges in scaling-up extraction of bioactive compounds require a parallel development of suitable analytical methods to monitor the process and ensure high yield and quality.
2020
127
115895
1
25
https://www.sciencedirect.com/science/article/pii/S0165993620301242?via=ihub
Extraction scale-up Ultrasonic-assisted extraction Supercritical fluid extraction Microwave-assisted extraction Batch to flow Bioactive compounds Green extraction
Belwal, T.; Chemat, F.; Venskutonis, P.R.; Cravotto, G.; Jaiswal, D.K.; Bhatt, I.D.; Devkota, H.P.; Luo, Z.
File in questo prodotto:
File Dimensione Formato  
Trens Analytical Chem 2020_postprint.docx

Open Access dal 05/05/2022

Descrizione: Articolo principale
Tipo di file: POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione 2.43 MB
Formato Microsoft Word XML
2.43 MB Microsoft Word XML Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1737959
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 97
  • ???jsp.display-item.citation.isi??? 84
social impact