Following an ST-elevation myocardial infarction (STEMI), a heightened predisposition to atherothrombotic events may persist for years.1 A growing body of evidence supports the prognostic value of complete over culprit-lesion-only revascularization among patients with STEMI and multivessel coronary artery disease (CAD).2,3 Whether the degree of angiographic obstruction or haemodynamical significance of a stenosis is a better marker to predict the evolution of a plaque towards clinically manifest atherothrombosis is unclear. Thus, which is the best between an angiography- vs. physiology-guided strategies to drive revascularization of non-culprit lesions following STEMI to prevent myocardial infarction (MI) and associated cardiovascular death (CVD) remains undefined. .....

Angiography- vs. physiology-guided complete revascularization in patients with ST-elevation myocardial infarction and multivessel disease: who is the better gatekeeper in this setting? A meta-analysis of randomized controlled trials

Gallone, Guglielmo;Angelini, Filippo;De Filippo, Ovidio;Giannini, Francesco;D'Ascenzo, Fabrizio;De Ferrari, Gaetano Maria
2020

Abstract

Following an ST-elevation myocardial infarction (STEMI), a heightened predisposition to atherothrombotic events may persist for years.1 A growing body of evidence supports the prognostic value of complete over culprit-lesion-only revascularization among patients with STEMI and multivessel coronary artery disease (CAD).2,3 Whether the degree of angiographic obstruction or haemodynamical significance of a stenosis is a better marker to predict the evolution of a plaque towards clinically manifest atherothrombosis is unclear. Thus, which is the best between an angiography- vs. physiology-guided strategies to drive revascularization of non-culprit lesions following STEMI to prevent myocardial infarction (MI) and associated cardiovascular death (CVD) remains undefined. .....
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Gallone, Guglielmo; Angelini, Filippo; Fortuni, Federico; Gnecchi, Massimiliano; De Filippo, Ovidio; Baldetti, Luca; Giannini, Francesco; Colombo, Antonio; D'Ascenzo, Fabrizio; De Ferrari, Gaetano Maria
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1739223
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