Normothermic ex vivo lung perfusion (EVLP) limits organ donor shortage by potentially using high-risk donor lungs. Microbial burden reduction has been demonstrated after EVLP using antibiotic prophylaxis with imipenem. However, no data have been published on the clinical consequences of the potential residual bacterial burden.
Impact of imipenem concentration in lung perfusate and tissue biopsy during clinical ex vivo lung perfusion (EVLP) of high-risk lung donors
Fanelli, Vito
;Boffini, Massimo;Costamagna, Andrea;Balzano, Stefano;Musso, Tiziana;Scutera, Sara;Cappello, Paola;Solidoro, Paolo;D'avolio, Antonio;Derosa, Francesco G;Brazzi, Luca;Rinaldi, Mauro;
2020-01-01
Abstract
Normothermic ex vivo lung perfusion (EVLP) limits organ donor shortage by potentially using high-risk donor lungs. Microbial burden reduction has been demonstrated after EVLP using antibiotic prophylaxis with imipenem. However, no data have been published on the clinical consequences of the potential residual bacterial burden.
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