Eu(HP-DO3A) is present in solution as a mixture of two diastereoisomers whose alcoholic groups are the source of the mobile protons for the CEST effect. The exchange is base catalyzed. Two novel EuIIIcomplexes of HP-DO3A-like ligands containing an amino or a carboxylate functionality in the proximity of the -OH groups showed the occurrence of intramolecular catalysis of the prototropic exchange. New insights into the role of the intramolecular proton exchange on the CEST properties have been gained.

H-Bonding and intramolecular catalysis of proton exchange affect the CEST properties of EuIIIcomplexes with HP-DO3A-like ligands

Baroni S.
First
;
Carnovale I. M.;Carrera C.;Aime S.
2021-01-01

Abstract

Eu(HP-DO3A) is present in solution as a mixture of two diastereoisomers whose alcoholic groups are the source of the mobile protons for the CEST effect. The exchange is base catalyzed. Two novel EuIIIcomplexes of HP-DO3A-like ligands containing an amino or a carboxylate functionality in the proximity of the -OH groups showed the occurrence of intramolecular catalysis of the prototropic exchange. New insights into the role of the intramolecular proton exchange on the CEST properties have been gained.
2021
57
26
3287
3290
CEST, Europium complex, H-bonding, intramolecular catalysis
Baroni S.; Carnovale I.M.; Carrera C.; Boccalon M.; Guidolin N.; Demitri N.; Lattuada L.; Tedoldi F.; Baranyai Z.; Aime S.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1793083
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