The 4D GRAPH-X (Dynamic GRAting-based PHase contrast x-ray imaging) project aims at developing a prototype of an x-ray grating-based phase-contrast imaging scanner in a laboratory setting, which is based on the Moire single-shot acquisition method in order to be optimized for analysing moving objects (in the specific case, a dynamic thorax phantom), that could evolve into a suitable tool for biomedical applications although it can be extended to other application fields. When designing an x-ray Talbot-Lau interferometer, high visibility and sensitivity are two important figures of merit, strictly related to the performance of the system in obtaining high quality phase contrast and dark-field images. Wave field simulations are performed to optimize the setup specifications and construct a high-resolution and high-sensitivity imaging system. In this work, the design of a dynamic imaging setup using a conventional milli-focus x-ray source is presented. Optimization by wave front simulations leads to a symmetric configuration with 5.25 mu m pitch at third Talbot order and 45 keV design energy. The simulated visibility is about 22%. Results from GATE based Monte Carlo simulations show a 19% transmission percentage of the incoming beam into the detector after passing through all the gratings and the sample. Such results are promising in view of building a system optimized for dynamic imaging.

X-ray grating interferometry design for the 4D GRAPH-X system

PATERA, ALESSANDRA;Ferrero, Veronica;Fiorina, Elisa;Lo Giudice, Alessandro;Mas Milian, Felix;Re, Alessandro;Visca, Lorenzo;Cerello, Piergiorgio
2021

Abstract

The 4D GRAPH-X (Dynamic GRAting-based PHase contrast x-ray imaging) project aims at developing a prototype of an x-ray grating-based phase-contrast imaging scanner in a laboratory setting, which is based on the Moire single-shot acquisition method in order to be optimized for analysing moving objects (in the specific case, a dynamic thorax phantom), that could evolve into a suitable tool for biomedical applications although it can be extended to other application fields. When designing an x-ray Talbot-Lau interferometer, high visibility and sensitivity are two important figures of merit, strictly related to the performance of the system in obtaining high quality phase contrast and dark-field images. Wave field simulations are performed to optimize the setup specifications and construct a high-resolution and high-sensitivity imaging system. In this work, the design of a dynamic imaging setup using a conventional milli-focus x-ray source is presented. Optimization by wave front simulations leads to a symmetric configuration with 5.25 mu m pitch at third Talbot order and 45 keV design energy. The simulated visibility is about 22%. Results from GATE based Monte Carlo simulations show a 19% transmission percentage of the incoming beam into the detector after passing through all the gratings and the sample. Such results are promising in view of building a system optimized for dynamic imaging.
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https://iopscience.iop.org/article/10.1088/1361-6463/ac2fd6/meta
x-ray phase contrast imaging; talbot-lau grating interferometer; dynamic imaging; wavefront simulation
PATERA, ALESSANDRA; Arboleda, Carolina; Ferrero, Veronica; Fiorina, Elisa; Jefimovs, Konstantins; Lo Giudice, Alessandro; Mas Milian, Felix; Mereu, Paolo; Pallotta, Stefania; Ramello, Luciano; Re, Alessandro; Visca, Lorenzo; Cerello, Piergiorgio
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1817659
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