Synaptic disruption precedes neuronal death and correlates with clinical features of Alzheimer's disease (AD). The identification of fluid biomarkers of synaptic damage is emerging as a goal for early and accurate diagnosis of the disease.
Synaptic Proteins as Fluid Biomarkers in Alzheimer's Disease: A Systematic Review and Meta-Analysis
Roveta, Fausto
;Cermelli, Aurora;Boschi, Silvia;Ferrandes, Fabio;Grassini, Alberto;Spina, Margherita;Rubino, Elisa;Vercelli, Alessandro;Rainero, Innocenzo
2022-01-01
Abstract
Synaptic disruption precedes neuronal death and correlates with clinical features of Alzheimer's disease (AD). The identification of fluid biomarkers of synaptic damage is emerging as a goal for early and accurate diagnosis of the disease.
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