A device for obtaining threedimensional cell cultures comprising: a sub strate (1); a plurality of micro-structures (2) which protrude from the surface of the sub strate (1) and are arranged on such substrate (1) according to a periodical grid so as to make the substrate (1) super hydrophobic. The device is characterised in that the micro-struc tures (2) have side walls at least partially nano-patterned and have projections (14) and recesses (16) alternated with a predetermined distance.
DEVICE FOR OBTAINING THREE-DIMENSIONAL CELL CULTURES, METHOD FOR THE IMPLEMENTATION THEREOF, AND USE OF SUCH DEVICE
LIMONGI Tania;
2013-01-01
Abstract
A device for obtaining threedimensional cell cultures comprising: a sub strate (1); a plurality of micro-structures (2) which protrude from the surface of the sub strate (1) and are arranged on such substrate (1) according to a periodical grid so as to make the substrate (1) super hydrophobic. The device is characterised in that the micro-struc tures (2) have side walls at least partially nano-patterned and have projections (14) and recesses (16) alternated with a predetermined distance.
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