BIOMIMETIC NON - IMMUNOGENIC NANOASSEMBLY FOR THE ANTITUMOR THERAPY

Nanoassembly ( 1 ) for inducing apoptosis in cancer cells comprising : a core ( 2 ) comprising at least a nanoparticle of a nano structured and semiconductor metal oxide , said nanoparticle being monocrystalline or polycrystalline ; a shell ( 3 ) formed by a double phospholipid layer and proteins derived from an extracellular biovesicole chosen between an exosome , an ectosome , a connectosome , an oncosome and an apoptotic body , and an oncosome , said core ( 2 ) being enclosed inside said shell ( 3 ) ; and a plurality of targeting molecules ( 4 , 4 ' , 4 " ) of said cancer cells , preferably mono clonal antibodies ( 4 , 4 ' , 4 " ) , said molecules ( 4 , 4 , 4 " ) being anchored to the external surface of said biovesicole .