We study the dynamics of Boolean networks of the scale-free type. The model takes into account the topology and abstracts recent findings about real genetic regulatory networks. We propose a new, more biologically plausible, semi-synchronous update scheme on networks of larger sizes. We simulate statistical ensembles of networks and discuss the attractors of the dynamics, showing that it is compatible with theoretical biological network models. Moreover, then model demonstrates interesting scaling abilities as the size of the networks is increased.

Semi-Synchronous Activation in Scale-Free Boolean Networks

GIACOBINI, Mario Dante Lucio;
2007-01-01

Abstract

We study the dynamics of Boolean networks of the scale-free type. The model takes into account the topology and abstracts recent findings about real genetic regulatory networks. We propose a new, more biologically plausible, semi-synchronous update scheme on networks of larger sizes. We simulate statistical ensembles of networks and discuss the attractors of the dynamics, showing that it is compatible with theoretical biological network models. Moreover, then model demonstrates interesting scaling abilities as the size of the networks is increased.
2007
Adavnces in Artificial Life: 9th European Conference, ECAL 2007
Lisbon, Portugal
September 2007
Proceedings of the 9th European Conference, ECAL 2007
Springer Verlag
4648
976
985
random boolean networks; irregular graphs; scale free; synchronocity; gene regulatory network modeling
Darabos, Ch; Giacobini, Mario Dante Lucio; Tomassini, M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/28064
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