Statins are widely used in the prevention of cardiovascular diseases, but they carry a risk of adverse muscle side effects, partly related to the decrease of coenzyme Q10. Chinese red rice (cholestatin) is a natural statin with apparent similar effects. What this study adds Chinese red rice reduced coenzyme Q10 in muscle tissue and mantained muscle damage in one patient previously treated with statins; it can not be considered an alternative therapy when statins are controindicated.

Chinese red rice depletes muscle coenzyme Q10 and maintains muscle damage after discontinuation of statin treatment

MONGINI, Tiziana Enrica;PALMUCCI, Laura Maria
2006

Abstract

Statins are widely used in the prevention of cardiovascular diseases, but they carry a risk of adverse muscle side effects, partly related to the decrease of coenzyme Q10. Chinese red rice (cholestatin) is a natural statin with apparent similar effects. What this study adds Chinese red rice reduced coenzyme Q10 in muscle tissue and mantained muscle damage in one patient previously treated with statins; it can not be considered an alternative therapy when statins are controindicated.
54
718
720
statins; myopathy; muscle biopsy
L. VERCELLI; T. MONGINI; N. OLIVERO; C. RODOLICO; O. MUSUMECI; L. PALMUCCI
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/41566
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