Hydroxyapatite powders characterized by substitutions of Mg2+, SiO4 4-, CO3 2- ions in biological like amounts, in the crystallographic site of calcium and phosphates, ions in biological like amounts, in the crystallographic site of calcium and phosphorus, were successfully prepared by synthesis in aqueous medium. The chemico-physical properties of the powders were investigated through several analytical techniques, among them: XRD, FTIR, TG-DTA, ICP-OES, HR-TEM. The entering of silicon in the HA structure progressively reduces its crystallinity, as also carbonate ions do. Silicate and carbonate ions can enter simultaneously into the HA structure, in biological-like amounts, although they compete for the occupation of the phosphate site. Solubility tests, carried out at physiological conditions, reveal an increased calcium release in the HA powders containing silicon compared to the silicon-free HA.

Development of multisustituted apatites for bone reconstruction

BERTINETTI, Luca;MARTRA, Gianmario
2008-01-01

Abstract

Hydroxyapatite powders characterized by substitutions of Mg2+, SiO4 4-, CO3 2- ions in biological like amounts, in the crystallographic site of calcium and phosphates, ions in biological like amounts, in the crystallographic site of calcium and phosphorus, were successfully prepared by synthesis in aqueous medium. The chemico-physical properties of the powders were investigated through several analytical techniques, among them: XRD, FTIR, TG-DTA, ICP-OES, HR-TEM. The entering of silicon in the HA structure progressively reduces its crystallinity, as also carbonate ions do. Silicate and carbonate ions can enter simultaneously into the HA structure, in biological-like amounts, although they compete for the occupation of the phosphate site. Solubility tests, carried out at physiological conditions, reveal an increased calcium release in the HA powders containing silicon compared to the silicon-free HA.
2008
International Congress on Bioceramics Materials - Bioceramics 20
Nantes
24-26 OTTOBRE 2007
Bioceramics 20
Transtech Publ. Ltd.
361-363
171
174
9780878494576
Non stoichiometric Hydroxyapatite; Silicon; Magnesium; Carbonate; Solubility
E. Landi; S. Sprio; A. Tampieri; L. Bertinetti; G. Martra
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/58532
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