The invention refers to a synthetic peptide comprising an amino acid sequence of seven residues in length, preferably flanked by 2 cysteine residues at both ends, which is capable of specifically recognizing human CD154 and blocking CD40:CD154 interaction, thereby inhibiting the biological effects depending on such interaction. The peptide of the invention, which is preferably in a cyclic form, is suitable for use for diagnostic and therapeutic applications, especially for the diagnosis and therapy of tumor, inflammatory diseases and transplant rejection

Human CD154-binding synthetic peptide and uses thereof

CAMUSSI, Giovanni;DEAMBROSIS, Ilaria
2007-01-01

Abstract

The invention refers to a synthetic peptide comprising an amino acid sequence of seven residues in length, preferably flanked by 2 cysteine residues at both ends, which is capable of specifically recognizing human CD154 and blocking CD40:CD154 interaction, thereby inhibiting the biological effects depending on such interaction. The peptide of the invention, which is preferably in a cyclic form, is suitable for use for diagnostic and therapeutic applications, especially for the diagnosis and therapy of tumor, inflammatory diseases and transplant rejection
2007
WO2009071486 (A1)
Fresenius Medical Care
http://ep.espacenet.com/
CD154; peptides
GIOVANNI CAMUSSI; ILARIA DEAMBROSIS
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/72939
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