The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.

Nanoparticles of therapeutic agents having low water solubility

DOSIO, Franco;STELLA, Barbara;CATTEL, Luigi
2009

Abstract

The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.
WO2009071850
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ;UNIVERSITE PARIS SUD VI ;COUVREUR Patrick; LAKKIREDDY, Harivardhan Reddy;DOSIO Franco;STELLA Barbara;CATTEL Luigi
nanoparticles; squalene; anticancer agents; self-assembly
Patrick COUVREUR; Harivardhan Reddy LAKKIREDDY; Franco DOSIO; Barbara STELLA; Luigi CATTEL
File in questo prodotto:
File Dimensione Formato  
WO2009071850A2.pdf

Accesso aperto

Tipo di file: POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione 1.63 MB
Formato Adobe PDF
1.63 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/76363
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact