In this paper, we present GLARE, a domain-independent system for acquiring, representing and executing clinical guidelines. GLARE is characterized by the adoption of Artificial Intelligence (AI) techniques at different levels in the definition and implementation of the system. First of all, a high-level and user-friendly knowledge representation language has been designed, providing a set of representation primitives. Second, a user-friendly acquisition tool has been designed and implemented, on the basis of the knowledge representation formalism. The acquisition tool provides various forms of help for the expert physicians, including different levels of syntactic and semantic tests in order to check the lsquolsquowell-formednessrsquorsquo of the guidelines being acquired. Third, a tool for executing guidelines on a specific patient has been made available. The execution module provides a hypothetical reasoning facility, to support physicians in the comparison of alternative diagnostic and/or therapeutic strategies. Moreover, advanced and extended AI techniques for temporal reasoning and temporal consistency checking are used both in the acquisition and in the execution phase. The GLARE approach has been successfully tested on clinical guidelines in different domains, including bladder cancer, reflux esophagitis, and heart failure.

Applying Artificial Intelligence to clinical guidelines: the GLARE approach

ANSELMA, LUCA;
2003

Abstract

In this paper, we present GLARE, a domain-independent system for acquiring, representing and executing clinical guidelines. GLARE is characterized by the adoption of Artificial Intelligence (AI) techniques at different levels in the definition and implementation of the system. First of all, a high-level and user-friendly knowledge representation language has been designed, providing a set of representation primitives. Second, a user-friendly acquisition tool has been designed and implemented, on the basis of the knowledge representation formalism. The acquisition tool provides various forms of help for the expert physicians, including different levels of syntactic and semantic tests in order to check the lsquolsquowell-formednessrsquorsquo of the guidelines being acquired. Third, a tool for executing guidelines on a specific patient has been made available. The execution module provides a hypothetical reasoning facility, to support physicians in the comparison of alternative diagnostic and/or therapeutic strategies. Moreover, advanced and extended AI techniques for temporal reasoning and temporal consistency checking are used both in the acquisition and in the execution phase. The GLARE approach has been successfully tested on clinical guidelines in different domains, including bladder cancer, reflux esophagitis, and heart failure.
8th Congress of the Italian Association for Artificial Intelligence
Pisa (Italia)
September 23-26, 2003
AI*IA 2003: Advances in Artificial Intelligence
Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229
2829
536
547
9783540201199
http://www.springerlink.com/content/pq1rt58tg1m9dpj4/#search=%22applying%20artificial%20intelligence%20to%20clinical%20guidelines%3a%20the%20glare%20approach%22
TERENZIANI P; MONTANI S; BOTTRIGHI A; TORCHIO M; MOLINO G; L. ANSELMA; CORRENDO G
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/8093
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 7
social impact