The invention relates to an isolated multipotent glomerular mesenchymal stem cell derived from adult human kidney (hGL-MSC), which is characterised by the marker profile CD133-, CD146+, CD34- and CD105+. A method of preparing the hGL-MSC of the invention form decapsulated glomeruli is also disclosed, as well as the uses of the hGL-MSC of the invention in the regenerative treatment of the kidney, particularly for the treatment of injuries or diseases affecting renal glomeruli.
ISOLATED MULTIPOTENT MESENCHYMAL STEM CELL FROM HUMAN ADULT GLOMERULI (HGL-MSC), A METHOD OF PREPARING THEREOF AND USES THEREOF IN THE REGENERATIVE MEDICINE OF THE KIDNEY
CAMUSSI, Giovanni;BRUNO, Stefania;BUSSOLATI, Benedetta
2011-01-01
Abstract
The invention relates to an isolated multipotent glomerular mesenchymal stem cell derived from adult human kidney (hGL-MSC), which is characterised by the marker profile CD133-, CD146+, CD34- and CD105+. A method of preparing the hGL-MSC of the invention form decapsulated glomeruli is also disclosed, as well as the uses of the hGL-MSC of the invention in the regenerative treatment of the kidney, particularly for the treatment of injuries or diseases affecting renal glomeruli.
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