Sfoglia per Autore
Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.
2012-01-01 Consonni A;Cipolla L;Guidetti G;Canobbio I;Ciraolo E;Hirsch E;Falasca M;Okigaki M;Balduini C;Torti M
Targeting PI3K in Cancer: Any Good News?
2013-01-01 Miriam Martini;Elisa Ciraolo;Federico Gulluni;Emilio Hirsch
The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.
2013-01-01 Cipolla L;Consonni A;Guidetti G;Canobbio I;Okigaki M;Falasca M;Ciraolo E;Hirsch E;Balduini C;Torti M
Methods to measure the enzymatic activity of PI3Ks.
2014-01-01 Ciraolo E;Gulluni F;Hirsch E
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function.
2014-01-01 Franco I;Gulluni F;Campa CC;Costa C;Margaria JP;Ciraolo E;Martini M;Monteyne D;De Luca E;Germena G;Posor Y;Maffucci T;Marengo S;Haucke V;Falasca M;Perez-Morga D;Boletta A;Merlo GR;Hirsch E
PI3K in cancer-stroma interactions: bad in seed and ugly in soil.
2014-01-01 Hirsch E;Ciraolo E;Franco I;Ghigo A;Martini M
Crossroads of PI3K and Rac pathways
2015-01-01 Campa, Carlo C; Ciraolo, Elisa; Ghigo, Alessandra; Germena, Giulia; Hirsch, Emilio
PI3K-C2γ 3 is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
2015-01-01 Braccini, Laura; Ciraolo, Elisa; Campa, Carlo C.; Perino, Alessia; Longo, Dario L.; Tibolla, Gianpaolo; Pregnolato, Marco; Cao, Yanyan; Tassone, Beatrice; Damilano, Federico; Laffargue, Muriel; Calautti, Vincenzo; Falasca, Marco; Norata, Giuseppe D.; Backer, Jonathan M.; Hirsch, Emilio
Hyper-activation of the Rho-GTPase Rac1 via disruption of ArhGAP15 results in reduced architectural and functional complexity
2015-01-01 Merlo, Giorgio R.; Armentano, Maria; Zamboni, Valentina; Sarò, Gabriella; Berto, Gaia; Ciraolo, Elisa; Ghigo, Alessandra; Passafaro, Maria; Carabelli, Valentina; Gavello, Daniela; El-Assawi, Nadia; Mauro, Alessandro; Priano, Lorenzo; Hirsch, Emilio
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease
2015-01-01 Galluzzo, Maria; Ciraolo, Elisa; Lucattelli, Monica; Hoxha, Eriola; Ulrich, Martina; Campa, Carlo Cosimo; Lungarella, Giuseppe; Doring, Gerd; Zhou-Suckow, Zhe; Mall, Marcus; Hirsch, Emilio; De Rose, Virginia
Rac signal adaptation controls neutrophil mobilization from the bone marrow
2016-01-01 Campa, Carlo Cosimo; Germena, Giulia; Ciraolo, Elisa; Copperi, Francesca; Sapienza, Anna; Franco, Irene; Ghigo, Alessandra; Camporeale, Annalisa; Di Savino, Augusta; Martini, Miriam; Perino, Alessia; Megens, Remco T.A.; Kurz, Angela R.M.; Scheiermann, Christoph; Sperandio, Markus; Gamba, Andrea; Hirsch, Emilio
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits
2016-01-01 Zamboni, Valentina; Armentano, Maria; Saró, Gabriella; Ciraolo, Elisa; Ghigo, Alessandra; Germena, Giulia; Umbach, Alessandro; Valnegri, Pamela; Passafaro, Maria; Carabelli, Valentina; Gavello, Daniela; Bianchi, Veronica; D'Adamo, Patrizia; De Curtis, Ivan; El-Assawi, Nadia; Mauro, Alessandro; Priano, Lorenzo; Ferri, Nicola; Hirsch, Emilio; Merlo, Giorgio R.
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs
2017-01-01 Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare
Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs
2017-01-01 Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
2017-01-01 Gulluni, Federico; Martini, Miriam; De Santis, Maria Chiara; Campa, Carlo Cosimo; Ghigo, Alessandra; Margaria, Jean Piero; Ciraolo, Elisa; Franco, Irene; Ala, Ugo; Annaratone, Laura; Disalvatore, Davide; Bertalot, Giovanni; Viale, Giuseppe; Noatynska, Anna; Compagno, Mara; Sigismund, Sara; Montemurro, Filippo; Thelen, Marcus; Fan, Fan; Meraldi, Patrick; Marchiò, Caterina; Pece, Salvatore; Sapino, Anna; Chiarle, Roberto; Di Fiore, Pier Paolo; Hirsch, Emilio
Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits
2018-01-01 Duarte, Larissa Jeremias; Chaves, Vitor Clasen; Nascimento, Marcus Vinicius Pereira dos Santos; Calvete, Eunice; Li, Mingchuan; Ciraolo, Elisa; Ghigo, Alessandra; Hirsch, Emilio; Simões, Claudia Maria Oliveira; Reginatto, Flávio Henrique; Dalmarco, Eduardo M.*
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
2018-01-01 Campa, Carlo C.; Silva, Rangel L.; Margaria, Jean P.; Pirali, Tracey; Mattos, Matheus S.; Kraemer, Lucas R.; Reis, Diego C.; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M.; Lima-Júnior, Roberto C. P.; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D.; Tron, Gian Cesare; Teixeira, Mauro M.; Ciraolo, Elisa; Russo, Remo C.; Hirsch, Emilio
Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics
2018-01-01 Zamboni, Valentina; Armentano, Maria; Berto, Gaia; Ciraolo, Elisa; Ghigo, Alessandra; Garzotto, Donatella; Umbach, Alessandro; Dicunto, Ferdinando; Parmigiani, Elena; Boido, Marina; Vercelli, Alessandro; El-Assawy, Nadia; Mauro, Alessandro; Priano, Lorenzo; Ponzoni, Luisa; Murru, Luca; Passafaro, Maria; Hirsch, Emilio*; Merlo, Giorgio R.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. | 2012 | Consonni A;Cipolla L;Guidetti G;Canobbio I;Ciraolo E;Hirsch E;Falasca M;Okigaki M;Balduini C;Torti M | |
| Targeting PI3K in Cancer: Any Good News? | 2013 | Miriam Martini;Elisa Ciraolo;Federico Gulluni;Emilio Hirsch | |
| The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling. | 2013 | Cipolla L;Consonni A;Guidetti G;Canobbio I;Okigaki M;Falasca M;Ciraolo E;Hirsch E;Balduini C;Torti M | |
| Methods to measure the enzymatic activity of PI3Ks. | 2014 | Ciraolo E;Gulluni F;Hirsch E | |
| PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. | 2014 | Franco I;Gulluni F;Campa CC;Costa C;Margaria JP;Ciraolo E;Martini M;Monteyne D;De Luca E;Germena G;Posor Y;Maffucci T;Marengo S;Haucke V;Falasca M;Perez-Morga D;Boletta A;Merlo GR;Hirsch E | |
| PI3K in cancer-stroma interactions: bad in seed and ugly in soil. | 2014 | Hirsch E;Ciraolo E;Franco I;Ghigo A;Martini M | |
| Crossroads of PI3K and Rac pathways | 2015 | Campa, Carlo C; Ciraolo, Elisa; Ghigo, Alessandra; Germena, Giulia; Hirsch, Emilio | |
| PI3K-C2γ 3 is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling | 2015 | Braccini, Laura; Ciraolo, Elisa; Campa, Carlo C.; Perino, Alessia; Longo, Dario L.; Tibolla, Gianpaolo; Pregnolato, Marco; Cao, Yanyan; Tassone, Beatrice; Damilano, Federico; Laffargue, Muriel; Calautti, Vincenzo; Falasca, Marco; Norata, Giuseppe D.; Backer, Jonathan M.; Hirsch, Emilio | |
| Hyper-activation of the Rho-GTPase Rac1 via disruption of ArhGAP15 results in reduced architectural and functional complexity | 2015 | Merlo, Giorgio R.; Armentano, Maria; Zamboni, Valentina; Sarò, Gabriella; Berto, Gaia; Ciraolo, Elisa; Ghigo, Alessandra; Passafaro, Maria; Carabelli, Valentina; Gavello, Daniela; El-Assawi, Nadia; Mauro, Alessandro; Priano, Lorenzo; Hirsch, Emilio | |
| Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease | 2015 | Galluzzo, Maria; Ciraolo, Elisa; Lucattelli, Monica; Hoxha, Eriola; Ulrich, Martina; Campa, Carlo Cosimo; Lungarella, Giuseppe; Doring, Gerd; Zhou-Suckow, Zhe; Mall, Marcus; Hirsch, Emilio; De Rose, Virginia | |
| Rac signal adaptation controls neutrophil mobilization from the bone marrow | 2016 | Campa, Carlo Cosimo; Germena, Giulia; Ciraolo, Elisa; Copperi, Francesca; Sapienza, Anna; Franco, Irene; Ghigo, Alessandra; Camporeale, Annalisa; Di Savino, Augusta; Martini, Miriam; Perino, Alessia; Megens, Remco T.A.; Kurz, Angela R.M.; Scheiermann, Christoph; Sperandio, Markus; Gamba, Andrea; Hirsch, Emilio | |
| Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits | 2016 | Zamboni, Valentina; Armentano, Maria; Saró, Gabriella; Ciraolo, Elisa; Ghigo, Alessandra; Germena, Giulia; Umbach, Alessandro; Valnegri, Pamela; Passafaro, Maria; Carabelli, Valentina; Gavello, Daniela; Bianchi, Veronica; D'Adamo, Patrizia; De Curtis, Ivan; El-Assawi, Nadia; Mauro, Alessandro; Priano, Lorenzo; Ferri, Nicola; Hirsch, Emilio; Merlo, Giorgio R. | |
| Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs | 2017 | Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare | |
| Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs | 2017 | Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare | |
| Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function | 2017 | Gulluni, Federico; Martini, Miriam; De Santis, Maria Chiara; Campa, Carlo Cosimo; Ghigo, Alessandra; Margaria, Jean Piero; Ciraolo, Elisa; Franco, Irene; Ala, Ugo; Annaratone, Laura; Disalvatore, Davide; Bertalot, Giovanni; Viale, Giuseppe; Noatynska, Anna; Compagno, Mara; Sigismund, Sara; Montemurro, Filippo; Thelen, Marcus; Fan, Fan; Meraldi, Patrick; Marchiò, Caterina; Pece, Salvatore; Sapino, Anna; Chiarle, Roberto; Di Fiore, Pier Paolo; Hirsch, Emilio | |
| Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits | 2018 | Duarte, Larissa Jeremias; Chaves, Vitor Clasen; Nascimento, Marcus Vinicius Pereira dos Santos; Calvete, Eunice; Li, Mingchuan; Ciraolo, Elisa; Ghigo, Alessandra; Hirsch, Emilio; Simões, Claudia Maria Oliveira; Reginatto, Flávio Henrique; Dalmarco, Eduardo M.* | |
| Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis | 2018 | Campa, Carlo C.; Silva, Rangel L.; Margaria, Jean P.; Pirali, Tracey; Mattos, Matheus S.; Kraemer, Lucas R.; Reis, Diego C.; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M.; Lima-Júnior, Roberto C. P.; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D.; Tron, Gian Cesare; Teixeira, Mauro M.; Ciraolo, Elisa; Russo, Remo C.; Hirsch, Emilio | |
| Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics | 2018 | Zamboni, Valentina; Armentano, Maria; Berto, Gaia; Ciraolo, Elisa; Ghigo, Alessandra; Garzotto, Donatella; Umbach, Alessandro; Dicunto, Ferdinando; Parmigiani, Elena; Boido, Marina; Vercelli, Alessandro; El-Assawy, Nadia; Mauro, Alessandro; Priano, Lorenzo; Ponzoni, Luisa; Murru, Luca; Passafaro, Maria; Hirsch, Emilio*; Merlo, Giorgio R. |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile