Sfoglia per Autore
Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress
2022-01-01 Mastrocola, Raffaella; Aimaretti, Eleonora; Ferreira Alves, Gustavo; Cento, Alessia Sofia; Fornelli, Claudia; Dal Bello, Federica; Ferraris, Chiara; Goitre, Luca; Perrelli, Andrea; Retta, Saverio Francesco
Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease
2020-01-01 Goitre L.; Fornelli C.; Zotta A.; Perrelli A.; Retta S.F.
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease
2019-01-01 Trapani, E; Antognelli, C; Delle Monache, S; Perrelli, A; Fornelli, C; Benedetti, V; Sarri, S; Costantino, G; Geddo, F; Zotta, A; Goitre, L; Retta, SF
Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases
2018-01-01 Perrelli, Andrea; Goitre, Luca; Salzano, Anna Maria; Moglia, Andrea; Scaloni, Andrea; Retta, Saverio Francesco
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations
2018-01-01 Fornelli, Claudia; Trapani, Eliana; Mastrocola, Raffaella; Perrelli, Andrea; Benedetti, Valerio; Zotta, Alessia; Costantino, Giulia; Geddo, Federica; Boda, Enrica; Biasi, Fiorella; Goitre, Luca; Retta, Saverio Francesco
Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications
2018-01-01 Trapani, Eliana; Antognelli, Cinzia; Goitre, Luca; Perrelli, Andrea; Sarri, Sara; Barrera, Giuseppina; Talesa, Vincenzo; Trabalzini, Lorenza; Retta, Saverio Francesco
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
2018-01-01 Antognelli, Cinzia*; Trapani, Eliana; Delle Monache, Simona; Perrelli, Andrea; Daga, Martina; Pizzimenti, Stefania; Barrera, Giuseppina; Cassoni, Paola; Angelucci, Adriano; Trabalzini, Lorenza; Talesa, Vincenzo Nicola; Goitre, Luca; Retta, Saverio Francesco
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease
2018-01-01 Perrelli, Andrea; Trapani, Eliana; Antognelli, Cinzia; Monache, Simona Delle; Fornelli, Claudia; Benedetti, Valerio; Costantino, Giulia; Geddo, Federica; Zotta, Alessia; Sarri, Sara; Bratti, Giovanna; Goitre, Luca; Retta, Saverio Francesco
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium
2017-01-01 Goitre, Luca; Distefano, Peter V.; Moglia, Andrea; Nobiletti, Nicholas; Baldini, Eva; Trabalzini, Lorenza; Keubel, Julie; Trapani, Eliana; Shuvaev, Vladimir V.; Muzykantov, Vladimir R.; Sarelius, Ingrid H.; Retta, Saverio Francesco; Glading, Angela J.
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies
2016-01-01 Marchi, Saverio; Trapani, Eliana; Corricelli, Mariangela; Goitre, Luca; Pinton, Paolo; Retta, Saverio Francesco
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1
2016-01-01 Choquet, Hélène; Trapani, Eliana; Goitre, Luca; Trabalzini, Lorenza; Akers, Amy; Fontanella, Marco; Hart, Blaine L.; Morrison, Leslie A.; Pawlikowska, Ludmila; Kim, Helen; Retta, Saverio Francesco
Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties
2016-01-01 Moglia, A.; Trapani, E.; Di Scipio, F.; Finetti, F.; Yang, Z.; Schiavo, I.; Goitre, L.; Baldini, E.; Donnini, S.; Trabalzini, L.; Berta, G.N.; Retta, S.F.
Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast
2015-01-01 Moglia, Andrea; Goitre, Luca; Gianoglio, Silvia; Baldini, Eva; Trapani, Eliana; Genre, Andrea; Scattina, Antonella; Dondo, Giancarlo; Trabalzini, Lorenza; Beekwilder, Jules; Retta, Saverio Francesco
Defective autophagy is a key feature of cerebral cavernous malformations
2015-01-01 Marchi, Saverio; Corricelli, Mariangela; Trapani, Eliana; Bravi, Luca; Pittaro, Alessandra; Delle Monache, Simona; Ferroni, Letizia; Patergnani, Simone; Missiroli, Sonia; Goitre, Luca; Trabalzini, Lorenza; Rimessi, Alessandro; Giorgi, Carlotta; Zavan, Barbara; Cassoni, Paola; Dejana, Elisabetta; Retta, Saverio Francesco; Pinton, Paolo
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation
2015-01-01 Gibson, Christopher C.; Zhu, Weiquan; Davis, Chadwick T.; Bowman-Kirigin, Jay A.; Chan, Aubrey C.; Ling, Jing; Walker, Ashley E.; Goitre, Luca; Monache, Simona Delle; Retta, Saverio Francesco; Shiu, Yan-Ting E.; Grossmann, Allie H.; Thomas, Kirk R.; Donato, Anthony J.; Lesniewski, Lisa A.; Whitehead, Kevin J.; Li, Dean Y.
Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties
2015-01-01 Moglia, A.; Trapani, E.; Yang, Z.; Di Scipio, F.; Goitre, L.; Trabalzini L., Baldini E.; Berta, G.N.; Retta, S.F.
Novel insights into the role of oxidative stress in CCM pathogenesis
2014-01-01 Goitre L.; Trapani E.; Choquet H.; Moglia A.; Marchi S.; Pinton P.; Delle Monache S.; Armeni T.; Antognelli C.; Fontanella M.; Baldini E.; Hart B.; Morrison L.; Gibson C.; Li D.Y.; Kim H.; Trabalzini L.; Retta S.F.
Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches
2014-01-01 Goitre L.; Moglia A.; Trapani E.; Marchi S.; Pinton P.; Delle Monache S.; Cianfruglia L.; Armeni T.; Principato G.; Antognelli C.; Talesa V.; Tognon M.; Fontanella M.; Baldini E.; Trabalzini L.; Li D.Y.; Retta S.F.
Metabolic engineering of Saccharomyces cerevisiae for the production of plant derived antioxidants
2014-01-01 Moglia A; Goitre L; Gianoglio S; Baldini E; Genre A; Trabalzini L; Beekwilder J; Retta SF
Combined Pulldown and Time-Lapse Microscopy Studies for Determining the Role of Rap1 in the Crosstalk Between Integrins and Cadherins
2014-01-01 Goitre, Luca; Retta, Saverio Francesco
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress | 2022 | Mastrocola, Raffaella; Aimaretti, Eleonora; Ferreira Alves, Gustavo; Cento, Alessia Sofia; Fornelli, Claudia; Dal Bello, Federica; Ferraris, Chiara; Goitre, Luca; Perrelli, Andrea; Retta, Saverio Francesco | |
| Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease | 2020 | Goitre L.; Fornelli C.; Zotta A.; Perrelli A.; Retta S.F. | |
| KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease | 2019 | Trapani, E; Antognelli, C; Delle Monache, S; Perrelli, A; Fornelli, C; Benedetti, V; Sarri, S; Costantino, G; Geddo, F; Zotta, A; Goitre, L; Retta, SF | |
| Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases | 2018 | Perrelli, Andrea; Goitre, Luca; Salzano, Anna Maria; Moglia, Andrea; Scaloni, Andrea; Retta, Saverio Francesco | |
| Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations | 2018 | Fornelli, Claudia; Trapani, Eliana; Mastrocola, Raffaella; Perrelli, Andrea; Benedetti, Valerio; Zotta, Alessia; Costantino, Giulia; Geddo, Federica; Boda, Enrica; Biasi, Fiorella; Goitre, Luca; Retta, Saverio Francesco | |
| Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications | 2018 | Trapani, Eliana; Antognelli, Cinzia; Goitre, Luca; Perrelli, Andrea; Sarri, Sara; Barrera, Giuseppina; Talesa, Vincenzo; Trabalzini, Lorenza; Retta, Saverio Francesco | |
| KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease | 2018 | Antognelli, Cinzia*; Trapani, Eliana; Delle Monache, Simona; Perrelli, Andrea; Daga, Martina; Pizzimenti, Stefania; Barrera, Giuseppina; Cassoni, Paola; Angelucci, Adriano; Trabalzini, Lorenza; Talesa, Vincenzo Nicola; Goitre, Luca; Retta, Saverio Francesco | |
| KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease | 2018 | Perrelli, Andrea; Trapani, Eliana; Antognelli, Cinzia; Monache, Simona Delle; Fornelli, Claudia; Benedetti, Valerio; Costantino, Giulia; Geddo, Federica; Zotta, Alessia; Sarri, Sara; Bratti, Giovanna; Goitre, Luca; Retta, Saverio Francesco | |
| Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium | 2017 | Goitre, Luca; Distefano, Peter V.; Moglia, Andrea; Nobiletti, Nicholas; Baldini, Eva; Trabalzini, Lorenza; Keubel, Julie; Trapani, Eliana; Shuvaev, Vladimir V.; Muzykantov, Vladimir R.; Sarelius, Ingrid H.; Retta, Saverio Francesco; Glading, Angela J. | |
| Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies | 2016 | Marchi, Saverio; Trapani, Eliana; Corricelli, Mariangela; Goitre, Luca; Pinton, Paolo; Retta, Saverio Francesco | |
| Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 | 2016 | Choquet, Hélène; Trapani, Eliana; Goitre, Luca; Trabalzini, Lorenza; Akers, Amy; Fontanella, Marco; Hart, Blaine L.; Morrison, Leslie A.; Pawlikowska, Ludmila; Kim, Helen; Retta, Saverio Francesco | |
| Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties | 2016 | Moglia, A.; Trapani, E.; Di Scipio, F.; Finetti, F.; Yang, Z.; Schiavo, I.; Goitre, L.; Baldini, E.; Donnini, S.; Trabalzini, L.; Berta, G.N.; Retta, S.F. | |
| Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast | 2015 | Moglia, Andrea; Goitre, Luca; Gianoglio, Silvia; Baldini, Eva; Trapani, Eliana; Genre, Andrea; Scattina, Antonella; Dondo, Giancarlo; Trabalzini, Lorenza; Beekwilder, Jules; Retta, Saverio Francesco | |
| Defective autophagy is a key feature of cerebral cavernous malformations | 2015 | Marchi, Saverio; Corricelli, Mariangela; Trapani, Eliana; Bravi, Luca; Pittaro, Alessandra; Delle Monache, Simona; Ferroni, Letizia; Patergnani, Simone; Missiroli, Sonia; Goitre, Luca; Trabalzini, Lorenza; Rimessi, Alessandro; Giorgi, Carlotta; Zavan, Barbara; Cassoni, Paola; Dejana, Elisabetta; Retta, Saverio Francesco; Pinton, Paolo | |
| Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation | 2015 | Gibson, Christopher C.; Zhu, Weiquan; Davis, Chadwick T.; Bowman-Kirigin, Jay A.; Chan, Aubrey C.; Ling, Jing; Walker, Ashley E.; Goitre, Luca; Monache, Simona Delle; Retta, Saverio Francesco; Shiu, Yan-Ting E.; Grossmann, Allie H.; Thomas, Kirk R.; Donato, Anthony J.; Lesniewski, Lisa A.; Whitehead, Kevin J.; Li, Dean Y. | |
| Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties | 2015 | Moglia, A.; Trapani, E.; Yang, Z.; Di Scipio, F.; Goitre, L.; Trabalzini L., Baldini E.; Berta, G.N.; Retta, S.F. | |
| Novel insights into the role of oxidative stress in CCM pathogenesis | 2014 | Goitre L.; Trapani E.; Choquet H.; Moglia A.; Marchi S.; Pinton P.; Delle Monache S.; Armeni T.; Antognelli C.; Fontanella M.; Baldini E.; Hart B.; Morrison L.; Gibson C.; Li D.Y.; Kim H.; Trabalzini L.; Retta S.F. | |
| Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches | 2014 | Goitre L.; Moglia A.; Trapani E.; Marchi S.; Pinton P.; Delle Monache S.; Cianfruglia L.; Armeni T.; Principato G.; Antognelli C.; Talesa V.; Tognon M.; Fontanella M.; Baldini E.; Trabalzini L.; Li D.Y.; Retta S.F. | |
| Metabolic engineering of Saccharomyces cerevisiae for the production of plant derived antioxidants | 2014 | Moglia A; Goitre L; Gianoglio S; Baldini E; Genre A; Trabalzini L; Beekwilder J; Retta SF | |
| Combined Pulldown and Time-Lapse Microscopy Studies for Determining the Role of Rap1 in the Crosstalk Between Integrins and Cadherins | 2014 | Goitre, Luca; Retta, Saverio Francesco |
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