Sfoglia per Autore
Targeting PI3Kγ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1
2026-01-01 Murabito A.; Mergiotti M.; Capurro V.; Loffreda A.; Li M.; Peretto P.; Ren K.; Raimondi A.; Tacchetti C.; Diviani D.; Pedemonte N.; Hirsch E.; Ghigo A.
Caught in the crossfire: cardiac complications of cancer therapy
2026-01-01 Guerra G.; Mergiotti M.; Ardehali H.; Hirsch E.; Ghigo A.
Biophysical and aerodynamic properties of a peptide targeting the A-kinase anchoring function of PI3Kγ for pulmonary cAMP modulation
2026-01-01 Della Sala, Angela; Sala, Valentina; Butnarasu, Cosmin Stefan; Tasca, Laura; Costabile, Gabriella; Mergiotti, Marco; Gramegna, Andrea; Blasi, Francesco; Aliberti, Stefano; Ungaro, Francesca; Visentin, Sonja; Hirsch, Emilio; Ghigo, Alessandra
Immunometabolism in heart failure
2025-01-01 Andreadou, Ioanna; Ghigo, Alessandra; Nikolaou, Panagiota-Efstathia; Swirski, Filip K; Thackeray, James T; Heusch, Gerd; Vilahur, Gemma
Dapagliflozin enhances hemodynamic and metabolic recovery following cardioplegic arrest in the isolated working mouse heart
2025-01-01 Dostal C.; Reiner J.; Spona D.; Wolner L.; Pilz P.M.; Weber L.; Yilmaz G.; Stampfer A.; Godel M.; Guerra G.; Ghigo A.; Kapeller B.; Riganti C.; Isabel Antunes Goncalves A.; Hallstrom S.; Kiss A.; Podesser B.K.
Update on preclinical models of cancer therapy-related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio-Oncology, and the ESC Working Group on Cellular Biology of the Heart
2025-01-01 Ghigo A.; Ameri P.; Asnani A.; Bertero E.; de Boer R.A.; Farmakis D.; Gonzalez A.; Heymans S.; Ibanez B.; Lopez-Fernandez T.; Lyon A.R.; Pollesello P.; Rakisheva A.; Stellos K.; Streckfuss-Bomeke K.; Tocchetti C.G.; Thum T.; van der Meer P.; Van Rooij E.; Ponikowski P.; Metra M.; Rosano G.; Van Linthout S.
Immune cell subtype contributions to doxorubicin cardiotoxicity-defining immune targets for translational interventions
2025-01-01 Van Fraeyenhove, Jens; Guerra, Giulia; Hirsch, Emilio; Ghigo, Alessandra
PI3K/Akt in IPF: untangling fibrosis and charting therapies
2025-01-01 Bhatt J.; Ghigo A.; Hirsch E.
Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia
2025-01-01 Angelino, Elia; Bodo, Lorenza; Sartori, Roberta; Malacarne, Valeria; D'Anna, Beatrice; Formaggio, Nicolò; Barua, Suvham; Raiteri, Tommaso; Lauria, Andrea; Reano, Simone; Murabito, Alessandra; Nicolau, Monica; Ferrero, Fabiana; Pezzini, Camilla; Rossino, Giulia; Favero, Francesco; Valmasoni, Michele; Filigheddu, Nicoletta; Menga, Alessio; Corà, Davide; Hirsch, Emilio; Oliviero, Salvatore; Sartorelli, Vittorio; Proserpio, Valentina; Ghigo, Alessandra; Sandri, Marco; Porporato, Paolo E.; Talarico, Daniela; Caretti, Giuseppina; Graziani, Andrea
Gut and faecal microbiota alterations in mice following infection with Arcobacter butzleri strains from a food processing plant
2025-01-01 Chiarini, Elisabetta; Della Sala, Angela; Buzzanca, Davide; Chiesa, Francesco; Capucchio, Maria Teresa; Hassan, Talal; Houf, Kurt; Ghigo, Alessandra; Alessandria, Valentina
Role of PDE4 Family in Cardiomyocyte Physiology and Heart Failure
2025-01-01 Sherstnev I.; Judina A.; Luciani G.B.; Ghigo A.; Hirsch E.; Gorelik J.
Stop Me at Your Own PeRiL: PRL2 Constrains AMPK in the Pressure-Overloaded Heart
2025-01-01 Bertero E.; Ghigo A.; Ameri P.
Inhibition of HuR/ELAVL-1 attenuates fibrotic progression in Mdx mice with dilated cardiomyopathy
2025-01-01 Farini, Andrea; Molinaro, Monica; Mostosi, Debora; Camera, Mattia; Russo, Michele; Leonetti, Emma; Meregalli, Mirella; Prandi, Lucia; Liaci, Carla; Ghigo, Alessandra; Hirsch, Emilio; Merlo, Giorgio; Torrente, Yvan
17(R)-RESOLVIN D1 PROTECTS AGAINST SICKLE CELL-RELATED INFLAMMATORY CARDIOMYOPATHY IN HUMANIZED MICE
2025-01-01 Federti, Enrica; Mattoscio, Domenico; Recchiuti, Antonio; Matte, Alessandro; Monti, Maria; Cozzolino, Flora; Iezzi, Manuela; Ceci, Martina; Ghigo, Alessandra; Tolosano, Emanuela; Siciliano, Angela; Ceolan, Jacopo; Riccardi, Veronica; Gremese, Elisa; Brugnara, Carlo; De Franceschi, Lucia
State of the art and perspectives of gene therapy in heart failure. A scientific statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial & Pericardial Diseases
2025-01-01 Van Linthout S.; Stellos K.; Giacca M.; Bertero E.; Cannata A.; Carrier L.; Garcia-Pavia P.; Ghigo A.; Gonzalez A.; Haugaa K.H.; Imazio M.; Lopes L.R.; Most P.; Pollesello P.; Schunkert H.; Streckfuss-Bomeke K.; Thum T.; Tocchetti C.G.; Tschope C.; van der Meer P.; van Rooij E.; Metra M.; Rosano G.M.C.; Heymans S.
Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure
2025-01-01 Kamel R.; Bourcier A.; Margaria J.P.; Jin V.; Varin A.; Hivonnait A.; Mercier-Nome F.; Mika D.; Ghigo A.; Charpentier F.; Algalarrondo V.; Hirsch E.; Fischmeister R.; Vandecasteele G.; Leroy J.
A nonnatural peptide targeting the A-kinase anchoring function of PI3Kg for therapeutic cAMP modulation in pulmonary cells
2024-01-01 Angela Della Sala, Laura Tasca, Cosmin Butnarasu, Valentina Sala, Giulia Prono, Alessandra Murabito, Olga Valentina Garbero, Enrico Millo, Leonardo Terranova, Francesco Blasi, Andrea Gramegna, Stefano Aliberti, Alberto Massarotti, Sonja Visentin, Emilio Hirsch, Alessandra Ghigo
Extracellular vesicles derived from human livers stem cells counteract chronic kidney disease development and cardiac dysfunction in remnant kidney murine model: the possible involvement of proteases
2024-01-01 Elena Ceccotti, Giulia Chiabotto, Massimo Cedrino, Alessandro Gambella, Luisa Delsedime, Alessandra Ghigo, Chiara Salio, Cristina Grange, Maria Beatriz Herrera Sanchez, Saveria Femminò, Marco Sassoè-Pognetto, Maria Felice Brizzi, Giovanni Camussi, Stefania Bruno
Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation
2024-01-01 Pavlaki, Nikoleta; Froese, Alexander; Li, Wener; De Jong, Kirstie A; Geertz, Birgit; Subramanian, Hariharan; Mohagaonkar, Sanika; Luo, Xiaojing; Schubert, Mario; Wiegmann, Robert; Margaria, Jean Piero; Ghigo, Alessandra; Kämmerer, Susanne; Hirsch, Emilio; El-Armouche, Ali; Guan, Kaomei; Nikolaev, Viacheslav O
An intrinsic mechanism of metabolic tuning promotes cardiac resilience to stress
2024-01-01 Sorge, Matteo; Savoré, Giulia; Gallo, Andrea; Acquarone, Davide; Sbroggiò, Mauro; Velasco, Silvia; Zamporlini, Federica; Femminò, Saveria; Moiso, Enrico; Morciano, Giampaolo; Balmas, Elisa; Raimondi, Andrea; Nattenberg, Gabrielle; Stefania, Rachele; Tacchetti, Carlo; Rizzo, Angela Maria; Corsetto, Paola; Ghigo, Alessandra; Turco, Emilia; Altruda, Fiorella; Silengo, Lorenzo; Pinton, Paolo; Raffaelli, Nadia; Sniadecki, Nathan J; Penna, Claudia; Pagliaro, Pasquale; Hirsch, Emilio; Riganti, Chiara; Tarone, Guido; Bertero, Alessandro; Brancaccio, Mara
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Targeting PI3Kγ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1 | 2026 | Murabito A.; Mergiotti M.; Capurro V.; Loffreda A.; Li M.; Peretto P.; Ren K.; Raimondi A.; Tacchetti C.; Diviani D.; Pedemonte N.; Hirsch E.; Ghigo A. | |
| Caught in the crossfire: cardiac complications of cancer therapy | 2026 | Guerra G.; Mergiotti M.; Ardehali H.; Hirsch E.; Ghigo A. | |
| Biophysical and aerodynamic properties of a peptide targeting the A-kinase anchoring function of PI3Kγ for pulmonary cAMP modulation | 2026 | Della Sala, Angela; Sala, Valentina; Butnarasu, Cosmin Stefan; Tasca, Laura; Costabile, Gabriella; Mergiotti, Marco; Gramegna, Andrea; Blasi, Francesco; Aliberti, Stefano; Ungaro, Francesca; Visentin, Sonja; Hirsch, Emilio; Ghigo, Alessandra | |
| Immunometabolism in heart failure | 2025 | Andreadou, Ioanna; Ghigo, Alessandra; Nikolaou, Panagiota-Efstathia; Swirski, Filip K; Thackeray, James T; Heusch, Gerd; Vilahur, Gemma | |
| Dapagliflozin enhances hemodynamic and metabolic recovery following cardioplegic arrest in the isolated working mouse heart | 2025 | Dostal C.; Reiner J.; Spona D.; Wolner L.; Pilz P.M.; Weber L.; Yilmaz G.; Stampfer A.; Godel M.; Guerra G.; Ghigo A.; Kapeller B.; Riganti C.; Isabel Antunes Goncalves A.; Hallstrom S.; Kiss A.; Podesser B.K. | |
| Update on preclinical models of cancer therapy-related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio-Oncology, and the ESC Working Group on Cellular Biology of the Heart | 2025 | Ghigo A.; Ameri P.; Asnani A.; Bertero E.; de Boer R.A.; Farmakis D.; Gonzalez A.; Heymans S.; Ibanez B.; Lopez-Fernandez T.; Lyon A.R.; Pollesello P.; Rakisheva A.; Stellos K.; Streckfuss-Bomeke K.; Tocchetti C.G.; Thum T.; van der Meer P.; Van Rooij E.; Ponikowski P.; Metra M.; Rosano G.; Van Linthout S. | |
| Immune cell subtype contributions to doxorubicin cardiotoxicity-defining immune targets for translational interventions | 2025 | Van Fraeyenhove, Jens; Guerra, Giulia; Hirsch, Emilio; Ghigo, Alessandra | |
| PI3K/Akt in IPF: untangling fibrosis and charting therapies | 2025 | Bhatt J.; Ghigo A.; Hirsch E. | |
| Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia | 2025 | Angelino, Elia; Bodo, Lorenza; Sartori, Roberta; Malacarne, Valeria; D'Anna, Beatrice; Formaggio, Nicolò; Barua, Suvham; Raiteri, Tommaso; Lauria, Andrea; Reano, Simone; Murabito, Alessandra; Nicolau, Monica; Ferrero, Fabiana; Pezzini, Camilla; Rossino, Giulia; Favero, Francesco; Valmasoni, Michele; Filigheddu, Nicoletta; Menga, Alessio; Corà, Davide; Hirsch, Emilio; Oliviero, Salvatore; Sartorelli, Vittorio; Proserpio, Valentina; Ghigo, Alessandra; Sandri, Marco; Porporato, Paolo E.; Talarico, Daniela; Caretti, Giuseppina; Graziani, Andrea | |
| Gut and faecal microbiota alterations in mice following infection with Arcobacter butzleri strains from a food processing plant | 2025 | Chiarini, Elisabetta; Della Sala, Angela; Buzzanca, Davide; Chiesa, Francesco; Capucchio, Maria Teresa; Hassan, Talal; Houf, Kurt; Ghigo, Alessandra; Alessandria, Valentina | |
| Role of PDE4 Family in Cardiomyocyte Physiology and Heart Failure | 2025 | Sherstnev I.; Judina A.; Luciani G.B.; Ghigo A.; Hirsch E.; Gorelik J. | |
| Stop Me at Your Own PeRiL: PRL2 Constrains AMPK in the Pressure-Overloaded Heart | 2025 | Bertero E.; Ghigo A.; Ameri P. | |
| Inhibition of HuR/ELAVL-1 attenuates fibrotic progression in Mdx mice with dilated cardiomyopathy | 2025 | Farini, Andrea; Molinaro, Monica; Mostosi, Debora; Camera, Mattia; Russo, Michele; Leonetti, Emma; Meregalli, Mirella; Prandi, Lucia; Liaci, Carla; Ghigo, Alessandra; Hirsch, Emilio; Merlo, Giorgio; Torrente, Yvan | |
| 17(R)-RESOLVIN D1 PROTECTS AGAINST SICKLE CELL-RELATED INFLAMMATORY CARDIOMYOPATHY IN HUMANIZED MICE | 2025 | Federti, Enrica; Mattoscio, Domenico; Recchiuti, Antonio; Matte, Alessandro; Monti, Maria; Cozzolino, Flora; Iezzi, Manuela; Ceci, Martina; Ghigo, Alessandra; Tolosano, Emanuela; Siciliano, Angela; Ceolan, Jacopo; Riccardi, Veronica; Gremese, Elisa; Brugnara, Carlo; De Franceschi, Lucia | |
| State of the art and perspectives of gene therapy in heart failure. A scientific statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial & Pericardial Diseases | 2025 | Van Linthout S.; Stellos K.; Giacca M.; Bertero E.; Cannata A.; Carrier L.; Garcia-Pavia P.; Ghigo A.; Gonzalez A.; Haugaa K.H.; Imazio M.; Lopes L.R.; Most P.; Pollesello P.; Schunkert H.; Streckfuss-Bomeke K.; Thum T.; Tocchetti C.G.; Tschope C.; van der Meer P.; van Rooij E.; Metra M.; Rosano G.M.C.; Heymans S. | |
| Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure | 2025 | Kamel R.; Bourcier A.; Margaria J.P.; Jin V.; Varin A.; Hivonnait A.; Mercier-Nome F.; Mika D.; Ghigo A.; Charpentier F.; Algalarrondo V.; Hirsch E.; Fischmeister R.; Vandecasteele G.; Leroy J. | |
| A nonnatural peptide targeting the A-kinase anchoring function of PI3Kg for therapeutic cAMP modulation in pulmonary cells | 2024 | Angela Della Sala, Laura Tasca, Cosmin Butnarasu, Valentina Sala, Giulia Prono, Alessandra Murabito, Olga Valentina Garbero, Enrico Millo, Leonardo Terranova, Francesco Blasi, Andrea Gramegna, Stefano Aliberti, Alberto Massarotti, Sonja Visentin, Emilio Hirsch, Alessandra Ghigo | |
| Extracellular vesicles derived from human livers stem cells counteract chronic kidney disease development and cardiac dysfunction in remnant kidney murine model: the possible involvement of proteases | 2024 | Elena Ceccotti, Giulia Chiabotto, Massimo Cedrino, Alessandro Gambella, Luisa Delsedime, Alessandra Ghigo, Chiara Salio, Cristina Grange, Maria Beatriz Herrera Sanchez, Saveria Femminò, Marco Sassoè-Pognetto, Maria Felice Brizzi, Giovanni Camussi, Stefania Bruno | |
| Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation | 2024 | Pavlaki, Nikoleta; Froese, Alexander; Li, Wener; De Jong, Kirstie A; Geertz, Birgit; Subramanian, Hariharan; Mohagaonkar, Sanika; Luo, Xiaojing; Schubert, Mario; Wiegmann, Robert; Margaria, Jean Piero; Ghigo, Alessandra; Kämmerer, Susanne; Hirsch, Emilio; El-Armouche, Ali; Guan, Kaomei; Nikolaev, Viacheslav O | |
| An intrinsic mechanism of metabolic tuning promotes cardiac resilience to stress | 2024 | Sorge, Matteo; Savoré, Giulia; Gallo, Andrea; Acquarone, Davide; Sbroggiò, Mauro; Velasco, Silvia; Zamporlini, Federica; Femminò, Saveria; Moiso, Enrico; Morciano, Giampaolo; Balmas, Elisa; Raimondi, Andrea; Nattenberg, Gabrielle; Stefania, Rachele; Tacchetti, Carlo; Rizzo, Angela Maria; Corsetto, Paola; Ghigo, Alessandra; Turco, Emilia; Altruda, Fiorella; Silengo, Lorenzo; Pinton, Paolo; Raffaelli, Nadia; Sniadecki, Nathan J; Penna, Claudia; Pagliaro, Pasquale; Hirsch, Emilio; Riganti, Chiara; Tarone, Guido; Bertero, Alessandro; Brancaccio, Mara |
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