CAMPA, CARLO COSIMO
CAMPA, CARLO COSIMO
BIOTECNOLOGIE MOLECOLARI E SCIENZE PER LA SALUTE
Crossroads of PI3K and Rac pathways
2015-01-01 Campa, Carlo C; Ciraolo, Elisa; Ghigo, Alessandra; Germena, Giulia; Hirsch, Emilio
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease
2015-01-01 Galluzzo, Maria; Ciraolo, Elisa; Lucattelli, Monica; Hoxha, Eriola; Ulrich, Martina; Campa, Carlo Cosimo; Lungarella, Giuseppe; Doring, Gerd; Zhou-Suckow, Zhe; Mall, Marcus; Hirsch, Emilio; De Rose, Virginia
How PI3K-derived lipids control cell division
2015-01-01 Campa, Carlo C; Martini, Miriam; De Santis, Maria C; Hirsch, Emilio
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs
2017-01-01 Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare
Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs
2017-01-01 Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
2018-01-01 Campa, Carlo C.; Silva, Rangel L.; Margaria, Jean P.; Pirali, Tracey; Mattos, Matheus S.; Kraemer, Lucas R.; Reis, Diego C.; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M.; Lima-Júnior, Roberto C. P.; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D.; Tron, Gian Cesare; Teixeira, Mauro M.; Ciraolo, Elisa; Russo, Remo C.; Hirsch, Emilio
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
2017-01-01 Gulluni, Federico; Martini, Miriam; De Santis, Maria Chiara; Campa, Carlo Cosimo; Ghigo, Alessandra; Margaria, Jean Piero; Ciraolo, Elisa; Franco, Irene; Ala, Ugo; Annaratone, Laura; Disalvatore, Davide; Bertalot, Giovanni; Viale, Giuseppe; Noatynska, Anna; Compagno, Mara; Sigismund, Sara; Montemurro, Filippo; Thelen, Marcus; Fan, Fan; Meraldi, Patrick; Marchiò, Caterina; Pece, Salvatore; Sapino, Anna; Chiarle, Roberto; Di Fiore, Pier Paolo; Hirsch, Emilio
Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation
2016-01-01 Franco, Irene; Margaria, Jean Piero; De Santis, Maria Chiara; Ranghino, Andrea; Monteyne, Daniel; Chiaravalli, Marco; Pema, Monika; Campa, Carlo Cosimo; Ratto, Edoardo; Gulluni, Federico; Perez-Morga, David; Somlo, Stefan; Merlo, Giorgio R; Boletta, Alessandra; Hirsch, Emilio
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function.
2014-01-01 Franco I;Gulluni F;Campa CC;Costa C;Margaria JP;Ciraolo E;Martini M;Monteyne D;De Luca E;Germena G;Posor Y;Maffucci T;Marengo S;Haucke V;Falasca M;Perez-Morga D;Boletta A;Merlo GR;Hirsch E
PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction
2015-01-01 Campa, Carlo C; Franco, Irene; Hirsch, Emilio
PI3K-C2γ 3 is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
2015-01-01 Braccini, Laura; Ciraolo, Elisa; Campa, Carlo C.; Perino, Alessia; Longo, Dario L.; Tibolla, Gianpaolo; Pregnolato, Marco; Cao, Yanyan; Tassone, Beatrice; Damilano, Federico; Laffargue, Muriel; Calautti, Vincenzo; Falasca, Marco; Norata, Giuseppe D.; Backer, Jonathan M.; Hirsch, Emilio
Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes
2018-01-01 Campa, Carlo Cosimo*; Margaria, Jean Piero; Derle, Abhishek; Del Giudice, Marco; De Santis, Maria Chiara; Gozzelino, Luca; Copperi, Francesca; Bosia, Carla; Hirsch, Emilio
Rab11 and phosphoinositides: A synergy of signal transducers in the control of vesicular trafficking
2017-01-01 Campa, Carlo Cosimo; Hirsch, Emilio
Rac signal adaptation controls neutrophil mobilization from the bone marrow
2016-01-01 Campa, Carlo Cosimo; Germena, Giulia; Ciraolo, Elisa; Copperi, Francesca; Sapienza, Anna; Franco, Irene; Ghigo, Alessandra; Camporeale, Annalisa; Di Savino, Augusta; Martini, Miriam; Perino, Alessia; Megens, Remco T.A.; Kurz, Angela R.M.; Scheiermann, Christoph; Sperandio, Markus; Gamba, Andrea; Hirsch, Emilio
Targeting PI3K signaling in cancer: Challenges and advances
2019-01-01 De Santis M.C.; Gulluni F.; Campa C.C.; Martini M.; Hirsch E.
The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium
2020-01-01 Margaria J.P.; Campa C.C.; De Santis M.C.; Hirsch E.; Franco I.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Crossroads of PI3K and Rac pathways | 2015 | Campa, Carlo C; Ciraolo, Elisa; Ghigo, Alessandra; Germena, Giulia; Hirsch, Emilio | |
| Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease | 2015 | Galluzzo, Maria; Ciraolo, Elisa; Lucattelli, Monica; Hoxha, Eriola; Ulrich, Martina; Campa, Carlo Cosimo; Lungarella, Giuseppe; Doring, Gerd; Zhou-Suckow, Zhe; Mall, Marcus; Hirsch, Emilio; De Rose, Virginia | |
| How PI3K-derived lipids control cell division | 2015 | Campa, Carlo C; Martini, Miriam; De Santis, Maria C; Hirsch, Emilio | |
| Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs | 2017 | Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare | |
| Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs | 2017 | Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare | |
| Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis | 2018 | Campa, Carlo C.; Silva, Rangel L.; Margaria, Jean P.; Pirali, Tracey; Mattos, Matheus S.; Kraemer, Lucas R.; Reis, Diego C.; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M.; Lima-Júnior, Roberto C. P.; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D.; Tron, Gian Cesare; Teixeira, Mauro M.; Ciraolo, Elisa; Russo, Remo C.; Hirsch, Emilio | |
| Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function | 2017 | Gulluni, Federico; Martini, Miriam; De Santis, Maria Chiara; Campa, Carlo Cosimo; Ghigo, Alessandra; Margaria, Jean Piero; Ciraolo, Elisa; Franco, Irene; Ala, Ugo; Annaratone, Laura; Disalvatore, Davide; Bertalot, Giovanni; Viale, Giuseppe; Noatynska, Anna; Compagno, Mara; Sigismund, Sara; Montemurro, Filippo; Thelen, Marcus; Fan, Fan; Meraldi, Patrick; Marchiò, Caterina; Pece, Salvatore; Sapino, Anna; Chiarle, Roberto; Di Fiore, Pier Paolo; Hirsch, Emilio | |
| Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation | 2016 | Franco, Irene; Margaria, Jean Piero; De Santis, Maria Chiara; Ranghino, Andrea; Monteyne, Daniel; Chiaravalli, Marco; Pema, Monika; Campa, Carlo Cosimo; Ratto, Edoardo; Gulluni, Federico; Perez-Morga, David; Somlo, Stefan; Merlo, Giorgio R; Boletta, Alessandra; Hirsch, Emilio | |
| PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. | 2014 | Franco I;Gulluni F;Campa CC;Costa C;Margaria JP;Ciraolo E;Martini M;Monteyne D;De Luca E;Germena G;Posor Y;Maffucci T;Marengo S;Haucke V;Falasca M;Perez-Morga D;Boletta A;Merlo GR;Hirsch E | |
| PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction | 2015 | Campa, Carlo C; Franco, Irene; Hirsch, Emilio | |
| PI3K-C2γ 3 is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling | 2015 | Braccini, Laura; Ciraolo, Elisa; Campa, Carlo C.; Perino, Alessia; Longo, Dario L.; Tibolla, Gianpaolo; Pregnolato, Marco; Cao, Yanyan; Tassone, Beatrice; Damilano, Federico; Laffargue, Muriel; Calautti, Vincenzo; Falasca, Marco; Norata, Giuseppe D.; Backer, Jonathan M.; Hirsch, Emilio | |
| Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes | 2018 | Campa, Carlo Cosimo*; Margaria, Jean Piero; Derle, Abhishek; Del Giudice, Marco; De Santis, Maria Chiara; Gozzelino, Luca; Copperi, Francesca; Bosia, Carla; Hirsch, Emilio | |
| Rab11 and phosphoinositides: A synergy of signal transducers in the control of vesicular trafficking | 2017 | Campa, Carlo Cosimo; Hirsch, Emilio | |
| Rac signal adaptation controls neutrophil mobilization from the bone marrow | 2016 | Campa, Carlo Cosimo; Germena, Giulia; Ciraolo, Elisa; Copperi, Francesca; Sapienza, Anna; Franco, Irene; Ghigo, Alessandra; Camporeale, Annalisa; Di Savino, Augusta; Martini, Miriam; Perino, Alessia; Megens, Remco T.A.; Kurz, Angela R.M.; Scheiermann, Christoph; Sperandio, Markus; Gamba, Andrea; Hirsch, Emilio | |
| Targeting PI3K signaling in cancer: Challenges and advances | 2019 | De Santis M.C.; Gulluni F.; Campa C.C.; Martini M.; Hirsch E. | |
| The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium | 2020 | Margaria J.P.; Campa C.C.; De Santis M.C.; Hirsch E.; Franco I. |