CINECA IRIS Institutional Research Information System

VIOLA, Franca Cecilia
 Distribuzione geografica
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Continente #
NA - Nord America 3.896
EU - Europa 2.432
AS - Asia 1.630
AF - Africa 65
SA - Sud America 53
Continente sconosciuto - Info sul continente non disponibili 11
OC - Oceania 4
Totale 8.091
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Nazione #
US - Stati Uniti d'America 3.850
CN - Cina 632
SG - Singapore 437
SE - Svezia 436
IE - Irlanda 363
DE - Germania 312
IT - Italia 252
KR - Corea 247
FI - Finlandia 234
UA - Ucraina 187
FR - Francia 183
AT - Austria 140
PL - Polonia 122
GB - Regno Unito 116
VN - Vietnam 115
JP - Giappone 101
SN - Senegal 59
BR - Brasile 44
CA - Canada 40
IN - India 38
RU - Federazione Russa 24
BE - Belgio 20
NL - Olanda 17
EU - Europa 11
ID - Indonesia 11
HK - Hong Kong 10
TH - Thailandia 8
UZ - Uzbekistan 7
PH - Filippine 6
TW - Taiwan 6
AU - Australia 4
CH - Svizzera 4
GR - Grecia 4
AR - Argentina 3
CZ - Repubblica Ceca 3
ES - Italia 3
IR - Iran 3
RS - Serbia 3
TR - Turchia 3
BD - Bangladesh 2
BY - Bielorussia 2
CU - Cuba 2
EC - Ecuador 2
EG - Egitto 2
MD - Moldavia 2
MX - Messico 2
NO - Norvegia 2
PK - Pakistan 2
AZ - Azerbaigian 1
CL - Cile 1
CO - Colombia 1
CR - Costa Rica 1
DZ - Algeria 1
JO - Giordania 1
LT - Lituania 1
MK - Macedonia 1
MU - Mauritius 1
PA - Panama 1
PY - Paraguay 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
VE - Venezuela 1
Totale 8.091
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Città #
Chandler 546
Beijing 432
Dublin 363
Ann Arbor 349
Santa Clara 317
Singapore 209
Jacksonville 187
Houston 150
Vienna 137
Dearborn 129
Princeton 123
Villeurbanne 119
Warsaw 118
Fairfield 111
Ashburn 108
Columbus 97
Medford 94
Dong Ket 91
Nyköping 81
Wilmington 78
Woodbridge 63
Boston 59
Fremont 50
Boardman 49
Munich 43
Seattle 43
Guangzhou 42
New York 42
Cambridge 41
Torino 39
Milan 33
Pisa 28
Düsseldorf 23
Norwalk 21
Redwood City 21
Brussels 20
Ottawa 19
Helsinki 15
Hangzhou 14
Hefei 14
Verona 13
Washington 13
Falls Church 11
Nanjing 11
Toronto 11
Changsha 10
Jakarta 10
Des Moines 9
Hong Kong 9
Los Angeles 9
Moscow 9
Mumbai 9
Rome 9
Fuzhou 8
Hebei 8
Kunming 8
Nanchang 8
Zhengzhou 8
Falkenstein 7
Lachine 7
San Diego 7
Tulsa 7
Menlo Park 6
Ogaki 6
Pune 6
Gangnam-gu 5
Nuremberg 5
Phoenix 5
Redmond 5
Shanghai 5
Taipei 5
Buffalo 4
Fondettes 4
Gwangjin-gu 4
Hanover 4
Indianapolis 4
Mountain View 4
Seongnam-si 4
Wuhan 4
Braunschweig 3
Formia 3
Frankfurt am Main 3
Fukuoka 3
Ho Chi Minh City 3
Iesi 3
Naaldwijk 3
Naples 3
Napoli 3
Palermo 3
San Mateo 3
São Paulo 3
Tokyo 3
Venezia 3
Amsterdam 2
Ardabil 2
Auburn Hills 2
Changchun 2
Chengdu 2
Contagem 2
Davao City 2
Totale 4.855
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Nome #
Regulation of HMGCoA reductase Activity by Policosanol and Octacosadienol, a New synthetic Analogue of Octacosanol 291
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 199
Predictive tests to evaluate oxidative potential of engineered nanomaterials 196
Stereospecific synthesis of squalenoid epoxide vinyl ethers as inhibitors of 2,3-oxidosqualene cyclase. 159
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 157
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping 155
Stereospecific synthesis of squalenoid epoxide vinyl ethers as inhibitors of 2,3-oxidosqualene cyclase 149
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 148
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 145
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 128
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 120
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 108
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 106
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 102
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 97
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 97
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors 94
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 93
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis. 92
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 92
Azasqualeni N-ossidi e bis-azasqualeni, inibitori dell'enzima squalene epossido ciclasi. 91
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 90
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 89
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 89
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae. 86
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors. 86
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 85
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 85
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 84
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 84
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 83
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 83
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 83
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase. 83
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. 82
2,3-Oxidosqualene cyclase and squalene epoxidase as target enzymes for the development of new sterol biosynthesis inhibitors 82
Characterization of C-4 demethylation complex of cholesterol biosynthesis 81
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 80
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. 80
Production and characterization of a monoclonal antibody reactive on the 2,3-epoxysqualene cyclase 80
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 80
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 80
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 80
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 79
3-carboxy-4-nitrophenyl-dithio-1,1'-2-trisnorsqualene: a site directed inactivator of yeast oxidosqualene cyclase 78
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 77
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 76
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 75
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 74
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 74
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 74
Thiol-modifying Inhibitors for Understanding Squalene Cyclase Function. Eur. J. Biochem. (2002) 269, 2108-2116. 73
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 73
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 73
Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives. 73
Thiol-modifying agents as tools for understanding the function of squalene cyclase 73
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase. 71
Studio comparato dell'attività inibitoria di derivati squalenoidi acetilenici ed allenici, nei confronti dell'enzima squalene epossidasi e delle monoossigenasi P-450 dipendenti. 71
Direzionamento di citotossine con anticorpi monoclonali per la terapia del cancro 70
Evidence of the existence of an essential thiol group within the active site of oxidosqualene cyclase from Saccharomyces cerevisiae 70
Comparison of the mechanism of yeast oxidosqualene cyclase and bacterial squalene cyclase by using rationally designed inhibitors. 69
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 67
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 67
Total synthesis and inhibition of sterol biosynthesis by 10-azasqualene 2,3-epoxide, a high-energy intermediate analogue 66
Soybean-germ oil inhibits oxidosqualene cyclase in 3T3 fibroblasts 65
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 65
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 65
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 64
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 63
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 63
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 63
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 62
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 62
policosanol: updating and perspectives 61
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 60
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 59
Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase. 58
Time-dependent inhibition of oxidosqualene cyclase by aza derivatives of squalene oxide. 57
Squalene- and nonsqualene-like thiol modifying agents as tools for understanding the function of squalene-hopene cyclase 57
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes. 56
Inhibition of sterol biosynthesis by an aza analogue of 2,3-oxidosqualene. 56
The squalene 2,3-epoxide cyclase as a model for the development of new drugs 56
Metabolismo ossidativo di azasqualeni. 56
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase. 53
Preparazione e attività antitumorale di un nuovo coniugato anticorpo-ricina ad alta specificità 53
In vivo metabolism of the anti-inflammatory agent 2-(ethylpyridin-2-yl)benzimidazole. 50
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 49
Synthesis of acetylenes and allenes, as inhibitors of squalene epoxidase. 48
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as inhibitors of liver and yeast oxidosqualene cyclase 44
New potent selective inhibitors of Trypanosoma cruzi oxidosqualene cyclase. 43
Selective inhibition of different enzymes of sterol biosynthesis by squalene derivatives 41
Inhibition of mammalian and yeast oxidosqualene cyclase by aza- and methylidene-derivatives of the substrate 40
Inhibition of serine proteases by a bisamide benzamidine lanthanide complex 39
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae by N,N-diethylazasqualene and derivatives 37
Rationally designed inhibitors as tools for comparing the mechanisms of squalene hopene cyclase and oxidosqualene cyclases 37
Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase 36
Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. 35
Stereospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase. 35
Totale 8.131
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Categoria #
all - tutte 26.816
article - articoli 0
book - libri 0
conference - conferenze 10.982
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.798
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020243 0 0 0 0 0 0 0 0 0 102 101 40
2020/2021803 112 36 37 45 91 42 39 19 101 43 82 156
2021/2022971 32 25 41 75 55 38 58 66 25 67 231 258
2022/20231.444 173 103 24 166 148 380 132 95 126 5 72 20
2023/2024518 80 113 34 28 28 71 8 36 2 13 20 85
2024/20251.111 10 53 36 161 517 50 22 92 169 1 0 0
Totale 8.397