CINECA IRIS Institutional Research Information System

VIOLA, Franca Cecilia
 Distribuzione geografica
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Continente #
NA - Nord America 3.311
EU - Europa 2.368
AS - Asia 1.221
AF - Africa 62
Continente sconosciuto - Info sul continente non disponibili 11
SA - Sud America 7
OC - Oceania 4
Totale 6.984
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Nazione #
US - Stati Uniti d'America 3.272
CN - Cina 611
SE - Svezia 435
IE - Irlanda 363
DE - Germania 285
IT - Italia 249
KR - Corea 234
FI - Finlandia 224
UA - Ucraina 187
FR - Francia 179
AT - Austria 137
PL - Polonia 122
GB - Regno Unito 113
VN - Vietnam 112
SG - Singapore 104
JP - Giappone 101
SN - Senegal 59
CA - Canada 35
IN - India 29
RU - Federazione Russa 23
BE - Belgio 20
EU - Europa 11
NL - Olanda 10
TH - Thailandia 8
UZ - Uzbekistan 6
BR - Brasile 5
AU - Australia 4
CH - Svizzera 4
GR - Grecia 4
ID - Indonesia 4
CZ - Repubblica Ceca 3
ES - Italia 3
IR - Iran 3
PH - Filippine 3
TW - Taiwan 3
CU - Cuba 2
EG - Egitto 2
MD - Moldavia 2
NO - Norvegia 2
RS - Serbia 2
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
CR - Costa Rica 1
MU - Mauritius 1
MX - Messico 1
PK - Pakistan 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
Totale 6.984
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Città #
Chandler 546
Beijing 432
Dublin 363
Ann Arbor 349
Jacksonville 187
Houston 150
Vienna 137
Dearborn 129
Princeton 123
Villeurbanne 119
Warsaw 118
Fairfield 111
Ashburn 94
Medford 94
Dong Ket 91
Nyköping 81
Wilmington 78
Woodbridge 63
Boston 59
Singapore 54
Fremont 50
Boardman 49
Seattle 43
New York 42
Cambridge 41
Torino 39
Munich 35
Milan 33
Guangzhou 29
Pisa 28
Düsseldorf 23
Norwalk 21
Redwood City 21
Brussels 20
Ottawa 16
Hangzhou 14
Hefei 14
Verona 13
Washington 13
Falls Church 11
Changsha 10
Des Moines 9
Moscow 9
Nanjing 9
Rome 9
Toronto 9
Fuzhou 8
Hebei 8
Kunming 8
Los Angeles 8
Nanchang 8
Zhengzhou 8
Lachine 7
San Diego 7
Tulsa 7
Menlo Park 6
Ogaki 6
Pune 6
Helsinki 5
Phoenix 5
Redmond 5
Shanghai 5
Buffalo 4
Hanover 4
Indianapolis 4
Mountain View 4
Wuhan 4
Formia 3
Fukuoka 3
Iesi 3
Jakarta 3
Naples 3
Napoli 3
Palermo 3
San Mateo 3
Tokyo 3
Venezia 3
Ardabil 2
Auburn Hills 2
Changchun 2
Chengdu 2
Davao City 2
Denver 2
Guri-si 2
Ho Chi Minh City 2
Jinan 2
La Habana 2
Leawood 2
Monmouth Junction 2
Nürnberg 2
Padova 2
Parma 2
Philadelphia 2
Recife 2
Saint Petersburg 2
Saronno 2
Shaoxing 2
Shenyang 2
Sydney 2
Taipei 2
Totale 4.191
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Nome #
Regulation of HMGCoA reductase Activity by Policosanol and Octacosadienol, a New synthetic Analogue of Octacosanol 259
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 188
Predictive tests to evaluate oxidative potential of engineered nanomaterials 178
Stereospecific synthesis of squalenoid epoxide vinyl ethers as inhibitors of 2,3-oxidosqualene cyclase. 148
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 143
Stereospecific synthesis of squalenoid epoxide vinyl ethers as inhibitors of 2,3-oxidosqualene cyclase 138
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 135
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 135
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping 134
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 111
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 111
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 97
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 91
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 90
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 88
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 88
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis. 84
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 81
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 79
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors 79
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 76
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors. 76
Azasqualeni N-ossidi e bis-azasqualeni, inibitori dell'enzima squalene epossido ciclasi. 76
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. 75
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 74
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae. 74
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 74
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 74
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 73
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 73
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 73
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 72
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 72
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 71
2,3-Oxidosqualene cyclase and squalene epoxidase as target enzymes for the development of new sterol biosynthesis inhibitors 71
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 71
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 70
Production and characterization of a monoclonal antibody reactive on the 2,3-epoxysqualene cyclase 70
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 70
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase. 70
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 69
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 69
Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives. 68
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 68
Characterization of C-4 demethylation complex of cholesterol biosynthesis 68
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 67
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 67
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 67
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. 66
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 65
Thiol-modifying agents as tools for understanding the function of squalene cyclase 65
Thiol-modifying Inhibitors for Understanding Squalene Cyclase Function. Eur. J. Biochem. (2002) 269, 2108-2116. 64
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 64
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 64
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 63
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 63
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 61
3-carboxy-4-nitrophenyl-dithio-1,1'-2-trisnorsqualene: a site directed inactivator of yeast oxidosqualene cyclase 61
Studio comparato dell'attività inibitoria di derivati squalenoidi acetilenici ed allenici, nei confronti dell'enzima squalene epossidasi e delle monoossigenasi P-450 dipendenti. 61
Total synthesis and inhibition of sterol biosynthesis by 10-azasqualene 2,3-epoxide, a high-energy intermediate analogue 59
Comparison of the mechanism of yeast oxidosqualene cyclase and bacterial squalene cyclase by using rationally designed inhibitors. 59
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 58
Soybean-germ oil inhibits oxidosqualene cyclase in 3T3 fibroblasts 57
Direzionamento di citotossine con anticorpi monoclonali per la terapia del cancro 57
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase. 56
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 56
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 55
Evidence of the existence of an essential thiol group within the active site of oxidosqualene cyclase from Saccharomyces cerevisiae 55
policosanol: updating and perspectives 55
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 54
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 54
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 53
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 53
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 52
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 51
Time-dependent inhibition of oxidosqualene cyclase by aza derivatives of squalene oxide. 51
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 50
Inhibition of sterol biosynthesis by an aza analogue of 2,3-oxidosqualene. 50
Preparazione e attività antitumorale di un nuovo coniugato anticorpo-ricina ad alta specificità 48
Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase. 48
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 48
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 48
Squalene- and nonsqualene-like thiol modifying agents as tools for understanding the function of squalene-hopene cyclase 47
The squalene 2,3-epoxide cyclase as a model for the development of new drugs 47
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase. 45
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes. 43
Metabolismo ossidativo di azasqualeni. 42
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as inhibitors of liver and yeast oxidosqualene cyclase 40
Synthesis of acetylenes and allenes, as inhibitors of squalene epoxidase. 38
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 38
New potent selective inhibitors of Trypanosoma cruzi oxidosqualene cyclase. 37
In vivo metabolism of the anti-inflammatory agent 2-(ethylpyridin-2-yl)benzimidazole. 37
Inhibition of mammalian and yeast oxidosqualene cyclase by aza- and methylidene-derivatives of the substrate 34
Rationally designed inhibitors as tools for comparing the mechanisms of squalene hopene cyclase and oxidosqualene cyclases 34
Stereospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase. 33
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae by N,N-diethylazasqualene and derivatives 33
Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. 32
Selective inhibition of different enzymes of sterol biosynthesis by squalene derivatives 32
Inhibition of serine proteases by a bisamide benzamidine lanthanide complex 32
Mutagenesi sito-specifica per lo studio di analogie strutturali tra squalene-opene ciclasi e ossidosqualene ciclasi. 31
Totale 7.054
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Categoria #
all - tutte 20.939
article - articoli 0
book - libri 0
conference - conferenze 8.514
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.453
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.084 35 57 88 80 80 205 150 42 104 102 101 40
2020/2021803 112 36 37 45 91 42 39 19 101 43 82 156
2021/2022971 32 25 41 75 55 38 58 66 25 67 231 258
2022/20231.444 173 103 24 166 148 380 132 95 126 5 72 20
2023/2024518 80 113 34 28 28 71 8 36 2 13 20 85
2024/20254 4 0 0 0 0 0 0 0 0 0 0 0
Totale 7.290