CINECA IRIS Institutional Research Information System

VIOLA, Franca Cecilia
 Distribuzione geografica
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Continente #
NA - Nord America 3.883
EU - Europa 2.395
AS - Asia 1.440
AF - Africa 63
Continente sconosciuto - Info sul continente non disponibili 11
SA - Sud America 7
OC - Oceania 4
Totale 7.803
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Nazione #
US - Stati Uniti d'America 3.841
CN - Cina 631
SE - Svezia 436
IE - Irlanda 363
DE - Germania 297
SG - Singapore 269
IT - Italia 250
KR - Corea 242
FI - Finlandia 227
UA - Ucraina 187
FR - Francia 183
AT - Austria 138
PL - Polonia 122
GB - Regno Unito 115
VN - Vietnam 112
JP - Giappone 101
SN - Senegal 59
IN - India 38
CA - Canada 37
RU - Federazione Russa 23
BE - Belgio 20
NL - Olanda 13
EU - Europa 11
ID - Indonesia 11
TH - Thailandia 8
TW - Taiwan 6
UZ - Uzbekistan 6
BR - Brasile 5
PH - Filippine 5
AU - Australia 4
CH - Svizzera 4
GR - Grecia 4
HK - Hong Kong 4
CZ - Repubblica Ceca 3
ES - Italia 3
IR - Iran 3
CU - Cuba 2
EG - Egitto 2
MD - Moldavia 2
NO - Norvegia 2
RS - Serbia 2
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
CR - Costa Rica 1
JO - Giordania 1
MU - Mauritius 1
MX - Messico 1
PA - Panama 1
PK - Pakistan 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
Totale 7.803
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Città #
Chandler 546
Beijing 432
Dublin 363
Ann Arbor 349
Santa Clara 317
Singapore 203
Jacksonville 187
Houston 150
Vienna 137
Dearborn 129
Princeton 123
Villeurbanne 119
Warsaw 118
Fairfield 111
Ashburn 108
Columbus 97
Medford 94
Dong Ket 91
Nyköping 81
Wilmington 78
Woodbridge 63
Boston 59
Fremont 50
Boardman 49
Munich 43
Seattle 43
Guangzhou 42
New York 42
Cambridge 41
Torino 39
Milan 33
Pisa 28
Düsseldorf 23
Norwalk 21
Redwood City 21
Brussels 20
Ottawa 18
Hangzhou 14
Hefei 14
Verona 13
Washington 13
Falls Church 11
Nanjing 11
Changsha 10
Jakarta 10
Des Moines 9
Los Angeles 9
Moscow 9
Mumbai 9
Rome 9
Toronto 9
Fuzhou 8
Hebei 8
Helsinki 8
Kunming 8
Nanchang 8
Zhengzhou 8
Lachine 7
San Diego 7
Tulsa 7
Menlo Park 6
Ogaki 6
Pune 6
Phoenix 5
Redmond 5
Shanghai 5
Taipei 5
Buffalo 4
Fondettes 4
Gwangjin-gu 4
Hanover 4
Indianapolis 4
Mountain View 4
Seongnam-si 4
Wuhan 4
Braunschweig 3
Formia 3
Fukuoka 3
Hong Kong 3
Iesi 3
Naaldwijk 3
Naples 3
Napoli 3
Palermo 3
San Mateo 3
Tokyo 3
Venezia 3
Ardabil 2
Auburn Hills 2
Changchun 2
Chengdu 2
Davao City 2
Denver 2
Frankfurt am Main 2
Guri-si 2
Ho Chi Minh City 2
Jinan 2
La Habana 2
Lanzhou 2
Leawood 2
Totale 4.819
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Nome #
Regulation of HMGCoA reductase Activity by Policosanol and Octacosadienol, a New synthetic Analogue of Octacosanol 279
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 196
Predictive tests to evaluate oxidative potential of engineered nanomaterials 192
Stereospecific synthesis of squalenoid epoxide vinyl ethers as inhibitors of 2,3-oxidosqualene cyclase. 156
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 154
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping 148
Stereospecific synthesis of squalenoid epoxide vinyl ethers as inhibitors of 2,3-oxidosqualene cyclase 146
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 144
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 141
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 126
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 118
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 106
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 105
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 99
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 95
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 93
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis. 91
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors 91
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 90
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 87
Azasqualeni N-ossidi e bis-azasqualeni, inibitori dell'enzima squalene epossido ciclasi. 87
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae. 84
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 84
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors. 83
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 83
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 82
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 82
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase. 82
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 82
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 81
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 80
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. 80
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 79
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 79
Production and characterization of a monoclonal antibody reactive on the 2,3-epoxysqualene cyclase 79
2,3-Oxidosqualene cyclase and squalene epoxidase as target enzymes for the development of new sterol biosynthesis inhibitors 79
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 79
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 78
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 78
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 78
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 77
3-carboxy-4-nitrophenyl-dithio-1,1'-2-trisnorsqualene: a site directed inactivator of yeast oxidosqualene cyclase 77
Characterization of C-4 demethylation complex of cholesterol biosynthesis 77
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. 76
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 76
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 76
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 74
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 74
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 73
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 73
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 72
Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives. 72
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 72
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 71
Thiol-modifying Inhibitors for Understanding Squalene Cyclase Function. Eur. J. Biochem. (2002) 269, 2108-2116. 70
Thiol-modifying agents as tools for understanding the function of squalene cyclase 70
Studio comparato dell'attività inibitoria di derivati squalenoidi acetilenici ed allenici, nei confronti dell'enzima squalene epossidasi e delle monoossigenasi P-450 dipendenti. 69
Comparison of the mechanism of yeast oxidosqualene cyclase and bacterial squalene cyclase by using rationally designed inhibitors. 68
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 68
Evidence of the existence of an essential thiol group within the active site of oxidosqualene cyclase from Saccharomyces cerevisiae 66
Total synthesis and inhibition of sterol biosynthesis by 10-azasqualene 2,3-epoxide, a high-energy intermediate analogue 65
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase. 65
Direzionamento di citotossine con anticorpi monoclonali per la terapia del cancro 64
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 64
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 64
Soybean-germ oil inhibits oxidosqualene cyclase in 3T3 fibroblasts 63
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 63
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 63
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 62
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 62
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 60
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 60
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 60
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 58
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 58
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 58
policosanol: updating and perspectives 58
Time-dependent inhibition of oxidosqualene cyclase by aza derivatives of squalene oxide. 56
Squalene- and nonsqualene-like thiol modifying agents as tools for understanding the function of squalene-hopene cyclase 55
Inhibition of sterol biosynthesis by an aza analogue of 2,3-oxidosqualene. 54
The squalene 2,3-epoxide cyclase as a model for the development of new drugs 54
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes. 53
Preparazione e attività antitumorale di un nuovo coniugato anticorpo-ricina ad alta specificità 53
Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase. 53
Metabolismo ossidativo di azasqualeni. 53
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase. 51
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 48
In vivo metabolism of the anti-inflammatory agent 2-(ethylpyridin-2-yl)benzimidazole. 46
Synthesis of acetylenes and allenes, as inhibitors of squalene epoxidase. 44
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as inhibitors of liver and yeast oxidosqualene cyclase 43
New potent selective inhibitors of Trypanosoma cruzi oxidosqualene cyclase. 41
Selective inhibition of different enzymes of sterol biosynthesis by squalene derivatives 39
Inhibition of mammalian and yeast oxidosqualene cyclase by aza- and methylidene-derivatives of the substrate 39
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae by N,N-diethylazasqualene and derivatives 37
Rationally designed inhibitors as tools for comparing the mechanisms of squalene hopene cyclase and oxidosqualene cyclases 37
Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase 36
Stereospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase. 35
Inhibition of serine proteases by a bisamide benzamidine lanthanide complex 35
Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. 34
Totale 7.853
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Categoria #
all - tutte 24.439
article - articoli 0
book - libri 0
conference - conferenze 10.019
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.458
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020744 0 0 0 0 0 205 150 42 104 102 101 40
2020/2021803 112 36 37 45 91 42 39 19 101 43 82 156
2021/2022971 32 25 41 75 55 38 58 66 25 67 231 258
2022/20231.444 173 103 24 166 148 380 132 95 126 5 72 20
2023/2024518 80 113 34 28 28 71 8 36 2 13 20 85
2024/2025823 10 53 36 161 517 46 0 0 0 0 0 0
Totale 8.109