GIORGIS, Marta
GIORGIS, Marta
SCIENZA E TECNOLOGIA DEL FARMACO
1,2,5-Oxadiazole analogues of leflunomide and related compounds
2011-01-01 Marta Giorgis; Marco Lucio Lolli; Barbara Rolando; Angela Rao; Paolo Tosco; Shilpi Chaurasia; Domenica Marabello; Roberta Fruttero; Alberto Gasco.
Amodiaquine analogues containing NO-donor substructures: Synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria
2011-01-01 Massimo Bertinaria; Stefano Guglielmo; Barbara Rolando; Marta Giorgis; Cristina Aragno; Roberta Fruttero; Alberto Gasco; Silvia Parapini; Donatella Taramelli; Yuri C. Martins; Leonardo J.M. Carvalho
Apoptotic and differentiating therapy for AML using potent human dihydroorotate dehydrogenase inhibitor
2021-01-01 Sainas Sainas, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lolli
Carnosine analogues containing NO-donor substructures: Synthesis, physico-chemical characterization and preliminary pharmacological profile
2012-01-01 Bertinaria M; Rolando B; Giorgis M; Montanaro G; Marini E; Collino M; Benetti E; Daniele PG; Fruttero R; Gasco A.
Carnosine analogues containing Phenol substructures
2012-01-01 Giorgis M.; Bertinaria M.; Rolando B.; Montanaro G.; Fruttero R.; Gasco A.
CC1000: a new cardioprotective agent against ischemia/reperfusion injuries
2006-01-01 A. Di Stilo; R. Rastaldo; M. Giorgis; G. Losano; A. Gasco
Chemical modifications of Tonda Gentile Trilobata hazelnut and derived processing products under different infrared and hot-air roasting conditions: a combined analytical study
2018-01-01 Arianna Binello, Marta Giorgis, Clara Cena, Giancarlo Cravotto, Laura Rotolo, Paolo Oliveri, Cristina Malegori, Maria Chiara Cavallero, Stefania Buso, Monica Casale
Chemical modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2h-benzo[d]imidazole-2-one scaffold as a novel NLRP3 inhibitor
2021-01-01 Gastaldi S.; Boscaro V.; Gianquinto E.; Sandall C.F.; Giorgis M.; Marini E.; Blua F.; Gallicchio M.; Spyrakis F.; Macdonald J.A.; Bertinaria M.
A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation
2018-01-01 Carolina Pellegrini, Matteo Fornai, Rocchina Colucci, Laura Benvenuti, Vanessa D’Antongiovanni, Gianfranco Natale, Federica Fulceri, Marta Giorgis, Elisabetta Marini, Simone Gastaldi, Massimo Bertinaria, Corrado Blandizzi, Luca Antonioli
Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors
2016-01-01 Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo
Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization
2021-01-01 Martino, Elena; Villella, Noemi;Vigato, Chiara; Cerrina, Matteo; Bersani, Matteo; Giorgis Marta, Sainas, Stefano.; Boschi, Donatella; Lolli, Marco Lucio
Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors
2016-01-01 Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
2017-01-01 Sainas, Stefano; Pippione, Agnese C.; Giorgis, Marta; Lupino, Elisa; Goyal, Parveen; Ramondetti, Cristina; Buccinnà, Barbara; Piccinini, Marco; Braga, Rodolpho C.; Andrade, Carolina H.; Andersson, Mikael; Moritzer, Ann-Christin; Friemann, Rosmarie; Mensa, Stefano; Al-Kadaraghi, Salam; Boschi, Donatella; Lolli, Marco L
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017-01-01 Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo
Development of covalent NLRP3 inflammasome inhibitors: chemistry and biological activity
2019-01-01 Bertinaria Massimo, Gastaldi Simone, Marini Elisabetta, Giorgis Marta
Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation
2018-01-01 Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli
A differentiating and apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor
2021-01-01 Stefano Sainas, Paola Circosta, Marta Giorgis, Agnese Chiara Pippione, Marilena Marraudino, Mohammad Houshmand, Brigitta Bonaldo, Valentina Gaidano, Alessandro Cignetti, Stefano Gotti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors.
2019-01-01 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Edaravone derivatives containing NO-donor functions
2009-01-01 Konstantin Chegaev; Clara Cena; Marta Giorgis; Barbara Rolando; Paolo Tosco; Massimo Bertinaria; Roberto Fruttero; Pier-Alain Carrupt; Alberto Gasco
The effect of hazelnut roasted skin from different cultivars on the quality attributes, polyphenol content and texture of fresh egg pasta
2015-01-01 Zeppa G.; Belviso S.; Bertolino M.; Cavallero M.C.; Dal Bello B.; Ghirardello D.; Giordano M.; Giorgis M.; Grosso A.; Rolle L.; Gerbi V.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,5-Oxadiazole analogues of leflunomide and related compounds | 2011 | Marta Giorgis; Marco Lucio Lolli; Barbara Rolando; Angela Rao; Paolo Tosco; Shilpi Chaurasia; Domenica Marabello; Roberta Fruttero; Alberto Gasco. | |
| Amodiaquine analogues containing NO-donor substructures: Synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria | 2011 | Massimo Bertinaria; Stefano Guglielmo; Barbara Rolando; Marta Giorgis; Cristina Aragno; Roberta Fruttero; Alberto Gasco; Silvia Parapini; Donatella Taramelli; Yuri C. Martins; Leonardo J.M. Carvalho | |
| Apoptotic and differentiating therapy for AML using potent human dihydroorotate dehydrogenase inhibitor | 2021 | Sainas Sainas, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lolli | |
| Carnosine analogues containing NO-donor substructures: Synthesis, physico-chemical characterization and preliminary pharmacological profile | 2012 | Bertinaria M; Rolando B; Giorgis M; Montanaro G; Marini E; Collino M; Benetti E; Daniele PG; Fruttero R; Gasco A. | |
| Carnosine analogues containing Phenol substructures | 2012 | Giorgis M.; Bertinaria M.; Rolando B.; Montanaro G.; Fruttero R.; Gasco A. | |
| CC1000: a new cardioprotective agent against ischemia/reperfusion injuries | 2006 | A. Di Stilo; R. Rastaldo; M. Giorgis; G. Losano; A. Gasco | |
| Chemical modifications of Tonda Gentile Trilobata hazelnut and derived processing products under different infrared and hot-air roasting conditions: a combined analytical study | 2018 | Arianna Binello, Marta Giorgis, Clara Cena, Giancarlo Cravotto, Laura Rotolo, Paolo Oliveri, Cristina Malegori, Maria Chiara Cavallero, Stefania Buso, Monica Casale | |
| Chemical modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2h-benzo[d]imidazole-2-one scaffold as a novel NLRP3 inhibitor | 2021 | Gastaldi S.; Boscaro V.; Gianquinto E.; Sandall C.F.; Giorgis M.; Marini E.; Blua F.; Gallicchio M.; Spyrakis F.; Macdonald J.A.; Bertinaria M. | |
| A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation | 2018 | Carolina Pellegrini, Matteo Fornai, Rocchina Colucci, Laura Benvenuti, Vanessa D’Antongiovanni, Gianfranco Natale, Federica Fulceri, Marta Giorgis, Elisabetta Marini, Simone Gastaldi, Massimo Bertinaria, Corrado Blandizzi, Luca Antonioli | |
| Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors | 2016 | Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo | |
| Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization | 2021 | Martino, Elena; Villella, Noemi;Vigato, Chiara; Cerrina, Matteo; Bersani, Matteo; Giorgis Marta, Sainas, Stefano.; Boschi, Donatella; Lolli, Marco Lucio | |
| Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors | 2016 | Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo | |
| Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds | 2017 | Sainas, Stefano; Pippione, Agnese C.; Giorgis, Marta; Lupino, Elisa; Goyal, Parveen; Ramondetti, Cristina; Buccinnà, Barbara; Piccinini, Marco; Braga, Rodolpho C.; Andrade, Carolina H.; Andersson, Mikael; Moritzer, Ann-Christin; Friemann, Rosmarie; Mensa, Stefano; Al-Kadaraghi, Salam; Boschi, Donatella; Lolli, Marco L | |
| Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease | 2017 | Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo | |
| Development of covalent NLRP3 inflammasome inhibitors: chemistry and biological activity | 2019 | Bertinaria Massimo, Gastaldi Simone, Marini Elisabetta, Giorgis Marta | |
| Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation | 2018 | Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli | |
| A differentiating and apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor | 2021 | Stefano Sainas, Paola Circosta, Marta Giorgis, Agnese Chiara Pippione, Marilena Marraudino, Mohammad Houshmand, Brigitta Bonaldo, Valentina Gaidano, Alessandro Cignetti, Stefano Gotti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors. | 2019 | Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| Edaravone derivatives containing NO-donor functions | 2009 | Konstantin Chegaev; Clara Cena; Marta Giorgis; Barbara Rolando; Paolo Tosco; Massimo Bertinaria; Roberto Fruttero; Pier-Alain Carrupt; Alberto Gasco | |
| The effect of hazelnut roasted skin from different cultivars on the quality attributes, polyphenol content and texture of fresh egg pasta | 2015 | Zeppa G.; Belviso S.; Bertolino M.; Cavallero M.C.; Dal Bello B.; Ghirardello D.; Giordano M.; Giorgis M.; Grosso A.; Rolle L.; Gerbi V. |