| Nome |
# |
|
Met-driven invasive growth involves transcriptional regulation of Arhgap12, file e27ce426-b6ca-2581-e053-d805fe0acbaa
|
775
|
|
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas., file e27ce427-ac78-2581-e053-d805fe0acbaa
|
548
|
|
Sustained Met signalling in the heart leads to cardiac compensated hypertrophy and remodelling, which evolves into congestive heart failure, file e27ce42b-cb9c-2581-e053-d805fe0acbaa
|
509
|
|
BRAF V600E is a determinant of sensitivity to proteasome inhibitors., file e27ce426-ffd1-2581-e053-d805fe0acbaa
|
481
|
|
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype, file e27ce430-1c84-2581-e053-d805fe0acbaa
|
475
|
|
Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration., file e27ce426-d4d1-2581-e053-d805fe0acbaa
|
467
|
|
MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases., file e27ce426-f87c-2581-e053-d805fe0acbaa
|
445
|
|
Stromal contribution to the colorectal cancer transcriptome., file e27ce427-4f59-2581-e053-d805fe0acbaa
|
408
|
|
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer, file e27ce42b-b6f8-2581-e053-d805fe0acbaa
|
371
|
|
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer, file e27ce42e-fdba-2581-e053-d805fe0acbaa
|
361
|
|
The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer., file e27ce426-ca59-2581-e053-d805fe0acbaa
|
303
|
|
Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts, file e27ce42c-7d72-2581-e053-d805fe0acbaa
|
260
|
|
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets, file e27ce426-9d7d-2581-e053-d805fe0acbaa
|
243
|
|
Transgenic models of cardiac cachexia and cardiac effects of muscular atrophy, file e27ce42b-a729-2581-e053-d805fe0acbaa
|
233
|
|
Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer, file e27ce426-d50c-2581-e053-d805fe0acbaa
|
223
|
|
Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions, file e27ce42b-9069-2581-e053-d805fe0acbaa
|
221
|
|
A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart, file e27ce429-b584-2581-e053-d805fe0acbaa
|
211
|
|
MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes, file e27ce427-a0cc-2581-e053-d805fe0acbaa
|
210
|
|
IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas, file e27ce42c-451d-2581-e053-d805fe0acbaa
|
209
|
|
VEGF blockade enhances the antitumor effect of BRAFV600E inhibition, file e27ce42b-2f9c-2581-e053-d805fe0acbaa
|
188
|
|
Detection of gene communities in multi-networks reveals cancer drivers, file e27ce428-32b2-2581-e053-d805fe0acbaa
|
186
|
|
The RNA-binding protein ESRP1 promotes human colorectal cancer progression, file e27ce42b-2c59-2581-e053-d805fe0acbaa
|
182
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|
Semalytics: a semantic analytics platform for the exploration of distributed and heterogeneous cancer data in translational research, file e27ce42e-a91c-2581-e053-d805fe0acbaa
|
178
|
|
A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells, file e27ce426-b1c3-2581-e053-d805fe0acbaa
|
175
|
|
A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer, file e27ce426-de44-2581-e053-d805fe0acbaa
|
165
|
|
Identification of p130Cas/ErbB2-dependent
invasive signatures in transformed
mammary epithelial cells, file e27ce426-fd2b-2581-e053-d805fe0acbaa
|
158
|
|
Transcriptional hallmarks of noonan syndrome and noonan-like syndrome with loose anagen hair, file e27ce426-d3d1-2581-e053-d805fe0acbaa
|
154
|
|
High-throughput molecular analysis from leftover of fine needle aspiration cytology of mammographically detected breast cancer., file e27ce426-e92c-2581-e053-d805fe0acbaa
|
153
|
|
Search for Neuro-Endocrine Markers (Chromogranin A, Synaptophysin and VGF) in Breast Cancers. An integrated Approach Using Immunohistochemistry and Gene Expression Profiling, file e27ce426-fe7e-2581-e053-d805fe0acbaa
|
153
|
|
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies., file e27ce428-9ce4-2581-e053-d805fe0acbaa
|
153
|
|
Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer, file e27ce426-bddd-2581-e053-d805fe0acbaa
|
152
|
|
Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes, file e27ce428-a106-2581-e053-d805fe0acbaa
|
152
|
|
A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells, file e27ce427-ab32-2581-e053-d805fe0acbaa
|
149
|
|
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology, file e27ce42e-7735-2581-e053-d805fe0acbaa
|
149
|
|
Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study, file e27ce427-0237-2581-e053-d805fe0acbaa
|
147
|
|
Patient-derived xenografts (PDXs) as model systems for human cancer, file e27ce42f-6f73-2581-e053-d805fe0acbaa
|
147
|
|
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients, file e27ce428-f6ea-2581-e053-d805fe0acbaa
|
145
|
|
STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK positive anaplastic large cell lymphoma., file e27ce428-e340-2581-e053-d805fe0acbaa
|
137
|
|
Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature, file e27ce426-fb12-2581-e053-d805fe0acbaa
|
136
|
|
Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models., file e27ce427-0f27-2581-e053-d805fe0acbaa
|
134
|
|
Exploiting orthologue diversity for systematic detection of gain-of-functionphenotypes, file e27ce426-b6c9-2581-e053-d805fe0acbaa
|
132
|
|
Formalin fixation at low temperature better preserves nucleic acid integrity., file e27ce426-dc43-2581-e053-d805fe0acbaa
|
130
|
|
Mulcom: a multiple comparison statistical test for microarray data in Bioconductor, file e27ce426-daf7-2581-e053-d805fe0acbaa
|
129
|
|
Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells., file e27ce428-a107-2581-e053-d805fe0acbaa
|
127
|
|
null, file e27ce430-c866-2581-e053-d805fe0acbaa
|
122
|
|
Electrical conditioning of adipose-derived stem cells in a multi-chamber culture platform, file e27ce428-e2ca-2581-e053-d805fe0acbaa
|
118
|
|
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies, file e27ce42d-ea3c-2581-e053-d805fe0acbaa
|
117
|
|
The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1., file e27ce42d-b5bf-2581-e053-d805fe0acbaa
|
106
|
|
Evolving neoantigen profiles in colorectal cancers with DNA repair defects, file e27ce42e-a91a-2581-e053-d805fe0acbaa
|
105
|
|
CSPG4-specific CAR.CIK lymphocytes as a novel therapy for the treatment of multiple soft tissue sarcoma histotypes, file e27ce430-b2f1-2581-e053-d805fe0acbaa
|
105
|
|
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis, file e27ce42b-20b8-2581-e053-d805fe0acbaa
|
91
|
|
MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer, file e27ce430-fc55-2581-e053-d805fe0acbaa
|
81
|
|
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, file e27ce431-0751-2581-e053-d805fe0acbaa
|
80
|
|
Isolation and Characterization of a Spontaneously Immortalized Multipotent Mesenchymal Cell Line Derived from Mouse Subcutaneous Adipose Tissue, file e27ce42a-0e94-2581-e053-d805fe0acbaa
|
79
|
|
The Dilemma of HER2 Double-equivocal Breast Carcinomas: Genomic Profiling and Implications for Treatment, file e27ce42d-320c-2581-e053-d805fe0acbaa
|
75
|
|
Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles, file e27ce430-fc54-2581-e053-d805fe0acbaa
|
75
|
|
A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin, file e27ce435-7e08-2581-e053-d805fe0acbaa
|
75
|
|
Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies, file e27ce42c-f513-2581-e053-d805fe0acbaa
|
74
|
|
Genetic and expression analysis of MET, MACC1 and HGF in metastatic colorectal cancer: Response to Met inhibition in patient xenografts and pathological correlations, file e27ce426-c2f8-2581-e053-d805fe0acbaa
|
68
|
|
Predicting locally advanced rectal cancer response to neoadjuvant therapy with 18 F-FDG PET and MRI radiomics features, file e27ce433-792b-2581-e053-d805fe0acbaa
|
68
|
|
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation, file e27ce432-7140-2581-e053-d805fe0acbaa
|
66
|
|
BRAF V600E is a determinant of sensitivity to proteasome inhibitors., file e27ce426-ffd2-2581-e053-d805fe0acbaa
|
63
|
|
Synthetic lethality screening highlights colorectal cancer vulnerability to concomitant blockade of nedd8 and egfr pathways, file e27ce432-6e6c-2581-e053-d805fe0acbaa
|
59
|
|
Dysregulation of MS risk genes and pathways at distinct stages of disease, file e27ce42d-4462-2581-e053-d805fe0acbaa
|
57
|
|
Only a subset of Met-activated pathways are required to sustain oncogene addiction, file e27ce426-c444-2581-e053-d805fe0acbaa
|
56
|
|
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer, file e27ce42a-bea3-2581-e053-d805fe0acbaa
|
48
|
|
Inhibition of Src impairs the growth of met-addicted gastric tumors., file e27ce426-ca70-2581-e053-d805fe0acbaa
|
43
|
|
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer, file e27ce42b-0741-2581-e053-d805fe0acbaa
|
42
|
|
The rna-binding protein esrp1 modulates the expression of rac1b in colorectal cancer cells, file e27ce432-9fd3-2581-e053-d805fe0acbaa
|
34
|
|
A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin, file e27ce42f-3951-2581-e053-d805fe0acbaa
|
30
|
|
The MET oncogene is a functional marker of a glioblastoma stem cell subtype., file e27ce426-d447-2581-e053-d805fe0acbaa
|
25
|
|
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine, file e27ce435-5c59-2581-e053-d805fe0acbaa
|
25
|
|
Successful treatment with MEK-inhibitor in a patient with NRAS-related cutaneous skeletal hypophosphatemia syndrome, file 0896349a-a018-4638-86d7-8bf5c47ffcac
|
22
|
|
PDX-MI: Minimal information for patient-derived tumor xenograft models, file e27ce42c-9a63-2581-e053-d805fe0acbaa
|
22
|
|
Mek inhibition in a newborn with raf1-associated noonan syndrome ameliorates hypertrophic cardiomyopathy but is insufficient to revert pulmonary vascular disease, file e27ce434-4ab5-2581-e053-d805fe0acbaa
|
19
|
|
Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity, file e8bd37d5-969c-4ca3-abe2-6d1e7c8b1c15
|
17
|
|
The EurOPDX Data Portal: an open platform for patient-derived cancer xenograft data sharing and visualization, file 021fdce9-fe2b-479d-8252-f176a6116ab2
|
16
|
|
A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy, file e27ce433-9c89-2581-e053-d805fe0acbaa
|
16
|
|
Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages, file 0f7b36ae-8da4-4965-9703-76f0c210267c
|
15
|
|
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, file e27ce431-0557-2581-e053-d805fe0acbaa
|
8
|
|
Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient, file d82de37f-401b-46a4-8b57-899917d6fc66
|
7
|
|
Isolation and Characterization of a Spontaneously Immortalized Multipotent Mesenchymal Cell Line Derived from Mouse Subcutaneous Adipose Tissue, file e27ce426-f0d9-2581-e053-d805fe0acbaa
|
7
|
|
A comprehensive PDX gastric cancer collection captures cancer cell intrinsic transcriptional MSI traits, file e27ce42f-0282-2581-e053-d805fe0acbaa
|
7
|
|
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology, file e27ce42e-7a1f-2581-e053-d805fe0acbaa
|
6
|
|
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, file 52c30ba5-92de-4264-8774-48ec22157379
|
5
|
|
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway, file b3425c6f-9300-4681-935d-21bf3dbec3fb
|
5
|
|
Stromal contribution to the colorectal cancer transcriptome., file e27ce426-9d30-2581-e053-d805fe0acbaa
|
5
|
|
Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer, file e27ce426-bddc-2581-e053-d805fe0acbaa
|
5
|
|
A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy, file e27ce42c-75e6-2581-e053-d805fe0acbaa
|
5
|
|
Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres, file dc4146ff-1c8b-40d4-b99a-a74791cae1ee
|
4
|
|
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies., file e27ce426-9d2c-2581-e053-d805fe0acbaa
|
4
|
|
Predicting locally advanced rectal cancer response to neoadjuvant therapy with 18 F-FDG PET and MRI radiomics features, file e27ce42e-7730-2581-e053-d805fe0acbaa
|
4
|
|
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer, file e27ce42a-e1bf-2581-e053-d805fe0acbaa
|
3
|
|
Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer, file 65129cae-8df7-4962-af31-5820fea87fe0
|
2
|
|
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets, file e27ce426-9d7e-2581-e053-d805fe0acbaa
|
2
|
|
Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer, file e27ce426-d50b-2581-e053-d805fe0acbaa
|
2
|
|
A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes, file e27ce431-379c-2581-e053-d805fe0acbaa
|
2
|
|
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer, file e27ce432-5370-2581-e053-d805fe0acbaa
|
2
|
|
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies, file e27ce432-5941-2581-e053-d805fe0acbaa
|
2
|
|
Only a subset of Met-activated pathways are required to sustain oncogene addiction, file e27ce426-c443-2581-e053-d805fe0acbaa
|
1
|
| Totale |
12.966 |