MEDICO, Enzo
 Distribuzione geografica
Continente #
NA - Nord America 11.970
EU - Europa 6.172
AS - Asia 3.683
OC - Oceania 81
SA - Sud America 53
AF - Africa 47
Continente sconosciuto - Info sul continente non disponibili 20
Totale 22.026
Nazione #
US - Stati Uniti d'America 11.789
CN - Cina 2.357
IT - Italia 2.047
DE - Germania 665
IE - Irlanda 576
SE - Svezia 482
GB - Regno Unito 415
FR - Francia 367
AT - Austria 301
JP - Giappone 299
UA - Ucraina 253
FI - Finlandia 241
KR - Corea 227
PL - Polonia 175
IN - India 168
VN - Vietnam 154
CA - Canada 148
BE - Belgio 114
SG - Singapore 111
NL - Olanda 109
DK - Danimarca 85
ES - Italia 85
TW - Taiwan 83
HK - Hong Kong 80
AU - Australia 73
CH - Svizzera 48
BR - Brasile 38
TH - Thailandia 36
IR - Iran 32
RO - Romania 31
RU - Federazione Russa 31
TR - Turchia 29
MX - Messico 28
SN - Senegal 26
PT - Portogallo 24
GR - Grecia 22
NO - Norvegia 22
CZ - Repubblica Ceca 19
MY - Malesia 18
EU - Europa 17
ID - Indonesia 17
IL - Israele 15
PK - Pakistan 11
HU - Ungheria 10
PH - Filippine 9
CL - Cile 8
NZ - Nuova Zelanda 8
UZ - Uzbekistan 8
RS - Serbia 7
ZA - Sudafrica 7
SK - Slovacchia (Repubblica Slovacca) 6
BA - Bosnia-Erzegovina 5
LU - Lussemburgo 5
BN - Brunei Darussalam 4
BY - Bielorussia 4
CO - Colombia 4
EG - Egitto 4
HR - Croazia 4
JO - Giordania 4
LK - Sri Lanka 4
MO - Macao, regione amministrativa speciale della Cina 4
NG - Nigeria 4
A1 - Anonimo 3
BG - Bulgaria 3
EE - Estonia 3
SA - Arabia Saudita 3
SI - Slovenia 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
AM - Armenia 2
AR - Argentina 2
DM - Dominica 2
GE - Georgia 2
KZ - Kazakistan 2
LT - Lituania 2
MK - Macedonia 2
BW - Botswana 1
CU - Cuba 1
GH - Ghana 1
GL - Groenlandia 1
HN - Honduras 1
IM - Isola di Man 1
KE - Kenya 1
KW - Kuwait 1
LB - Libano 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
MT - Malta 1
NA - Namibia 1
TZ - Tanzania 1
VE - Venezuela 1
Totale 22.026
Città #
Ann Arbor 2.558
Chandler 1.096
Fairfield 918
Beijing 793
Houston 738
Ashburn 574
Dublin 557
Torino 477
Woodbridge 435
Seattle 377
Cambridge 346
Wilmington 346
Shanghai 272
Vienna 262
Dearborn 250
Redwood City 214
Pisa 204
Nyköping 203
Villeurbanne 177
Jacksonville 166
Medford 163
Princeton 152
Guangzhou 147
Warsaw 142
New York 117
Milan 113
Turin 112
Tokyo 108
Hangzhou 102
Dong Ket 89
Fremont 79
Nanjing 72
Wuhan 68
San Diego 67
Boston 66
Brussels 64
Taipei 55
Genoa 53
Boardman 49
Rome 48
Shenyang 46
Eitensheim 41
Singapore 39
Toronto 39
Chengdu 37
London 37
Ottawa 37
Changsha 36
Amsterdam 35
Norwalk 35
Phoenix 35
Zhengzhou 34
Nanchang 32
Helsinki 30
Paris 30
Munich 29
Verona 29
Xian 29
Falls Church 27
Jinan 27
Kunming 27
Washington 27
Bangkok 26
Buffalo 26
Seoul 25
Silver Spring 25
Fuzhou 23
Chongqing 22
Southend 22
Los Angeles 21
Hefei 20
Mountain View 20
Belfast 19
Melbourne 19
Florence 18
Bologna 17
Central District 17
Düsseldorf 17
Heidelberg 17
Upper Marlboro 17
Berlin 16
Hong Kong 16
Hyderabad 16
Shenzhen 16
Rochester 15
Barcelona 14
Bengaluru 14
Central 14
Chicago 14
Tianjin 14
Carrara 13
Guiyang 13
New Delhi 13
Pittsburgh 13
Utrecht 13
Changchun 12
Harbin 12
Luni 12
Nashville 12
Oslo 12
Totale 14.212
Nome #
Stromal contribution to the colorectal cancer transcriptome. 1.750
Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer 711
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies. 672
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer 637
A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer 570
Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer 547
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology 534
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets 480
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. 480
MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases. 366
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients 357
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer 318
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer 307
MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes 288
Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts 275
BRAF V600E is a determinant of sensitivity to proteasome inhibitors. 252
The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer. 239
Only a subset of Met-activated pathways are required to sustain oncogene addiction 233
Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells. 232
Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions 228
Genetic and expression analysis of MET, MACC1 and HGF in metastatic colorectal cancer: Response to Met inhibition in patient xenografts and pathological correlations 216
Transcriptional hallmarks of noonan syndrome and noonan-like syndrome with loose anagen hair 214
Analisi del profilo di trascrizione genetica nella sindrome di Noonan. 213
Met-driven invasive growth involves transcriptional regulation of Arhgap12 211
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis 210
Transgenic models of cardiac cachexia and cardiac effects of muscular atrophy 209
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype 205
A comprehensive PDX gastric cancer collection captures cancer cell intrinsic transcriptional MSI traits 203
VEGF blockade enhances the antitumor effect of BRAFV600E inhibition 203
The RNA-binding protein ESRP1 promotes human colorectal cancer progression 202
Inhibition of Src impairs the growth of met-addicted gastric tumors. 196
null 196
The MET oncogene is a functional marker of a glioblastoma stem cell subtype. 193
High-throughput molecular analysis from leftover of fine needle aspiration cytology of mammographically detected breast cancer. 186
Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells 186
Evolving neoantigen profiles in colorectal cancers with DNA repair defects 183
A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells 175
A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin 174
Exploiting orthologue diversity for systematic detection of gain-of-functionphenotypes 172
Electrical conditioning of adipose-derived stem cells in a multi-chamber culture platform 172
Sustained Met signalling in the heart leads to cardiac compensated hypertrophy and remodelling, which evolves into congestive heart failure 171
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies 171
STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK positive anaplastic large cell lymphoma. 170
Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature 165
Mulcom: a multiple comparison statistical test for microarray data in Bioconductor 165
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts 164
Detection of gene communities in multi-networks reveals cancer drivers 163
A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy 162
Predicting locally advanced rectal cancer response to neoadjuvant therapy with 18 F-FDG PET and MRI radiomics features 160
Isolation and Characterization of a Spontaneously Immortalized Multipotent Mesenchymal Cell Line Derived from Mouse Subcutaneous Adipose Tissue 158
Generation of Functional Hepatocytes from Mouse Germline Cell-derived Pluripotent Stem Cells in vitro 151
A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart 149
A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells 147
IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas 143
Knock-in of oncogenic Kras does not transform mouse somatic cells but triggers a transcriptional response that classifies human cancers 135
Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models. 135
Semalytics: a semantic analytics platform for the exploration of distributed and heterogeneous cancer data in translational research 135
Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study 135
Patient-derived xenografts (PDXs) as model systems for human cancer 134
Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles 132
Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies 131
The Dilemma of HER2 Double-equivocal Breast Carcinomas: Genomic Profiling and Implications for Treatment 131
Knock-in of oncogenic mutations in human somatic cells as a tool to identify genoselective compounds 123
Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes 123
Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. 122
A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis. 121
PDX-MI: Minimal information for patient-derived tumor xenograft models 118
The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1. 118
Amplification of repeat-containing transcribed sequences (ARTS): a transcriptome fingerprinting strategy to detect functionally relevant microsatellite mutations in cancer. 117
Search for Neuro-Endocrine Markers (Chromogranin A, Synaptophysin and VGF) in Breast Cancers. An integrated Approach Using Immunohistochemistry and Gene Expression Profiling 117
Transcriptional signature of Pseudomyxoma Peritonei: An enhancement of treatment strategy and outcome prediction 113
The heme biosynthesis-heme export axis is required for the modulation of the tricarboxylic acid cycle 112
Formalin fixation at low temperature better preserves nucleic acid integrity. 109
The miR-126 regulates Angiopoietin-1 signaling and vessel maturation by targeting p85β 107
Gene expression profiling of HGF/Met activation in neonatal mouse heart 105
EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES 102
A gene trap vector system for identifying transcriptionally responsive genes 102
Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib 99
Reverse signaling by semaphorin 4C elicits SMAD1/5- And ID1/3-dependent invasive reprogramming in cancer cells 99
MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer 96
Cancer and blood coagulation 95
Genome-wide analysis of unliganded estrogen receptor binding sites in breast cancer cells 94
CSPG4-specific CAR.CIK lymphocytes as a novel therapy for the treatment of multiple soft tissue sarcoma histotypes 94
Biochemical and immunological properties of the human carcinoma-associated CAR-3 epitope defined by the monoclonal antibody AR-3. 93
Biochemical and immunological properties of the human carcinoma antigen CAR-5 defined by the monoclonal antibody BD-5. 93
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses 91
Modeling tumor progression and identifying genotype-drug interactions by the sequential introduction of cancer mutations into the genome of human normal cells 90
A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes 88
Integration of transcriptomic data and metabolic networks in cancer samples reveals highly significant prognostic power 87
The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells. 85
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation 84
Mek1 inhibition in vivo mitigates progressive cardiac concentric hypertrophy promoted by activated Met receptor. 83
The tyrosine kinase receptor met and its ligand HGF are co-expressed and functionally active in HHV-8 positive primary effusion lymphoma. 80
Anaplastic large-cell lymphoma 79
Structural and functional domains critical for constitutive activation of the HGF-receptor (Met). 78
The MET oncogene drives a genetic programme linking cancer to haemostasis 76
Molecular anatomy of peripheral T cell lymphomas 76
The heme exporter FLVCR1a modulates the tricarboxylic acid cycle: a new target in colorectal cancer 76
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle 73
Metabolic adaptation in colorectal cancer: heme export is required for the modulation of the tricarboxylic acid cycle. 73
Totale 20.393
Categoria #
all - tutte 46.868
article - articoli 0
book - libri 0
conference - conferenze 5.220
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.088


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.123 0 0 0 0 0 0 0 0 0 243 566 314
2019/20203.554 248 167 216 459 272 606 348 263 332 294 199 150
2020/20213.104 172 191 261 188 218 270 349 173 266 292 196 528
2021/20224.807 488 434 415 502 366 335 428 350 224 217 614 434
2022/20233.548 363 296 102 329 321 738 223 256 446 95 220 159
2023/20241.830 248 276 141 165 163 303 158 226 56 94 0 0
Totale 22.567