| Nome |
# |
|
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction., file e27ce426-f7cd-2581-e053-d805fe0acbaa
|
944
|
|
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis, file e27ce42a-a03e-2581-e053-d805fe0acbaa
|
821
|
|
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress, file e27ce42b-c2fd-2581-e053-d805fe0acbaa
|
530
|
|
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases, file e27ce426-df79-2581-e053-d805fe0acbaa
|
496
|
|
Cytokinetic abscission: Phosphoinositides and ESCRTs direct the final cut, file e27ce42b-6de6-2581-e053-d805fe0acbaa
|
392
|
|
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia, file e27ce435-0722-2581-e053-d805fe0acbaa
|
280
|
|
Morgana acts as an oncosuppressor in chronic myeloid leukemia., file e27ce42a-6732-2581-e053-d805fe0acbaa
|
269
|
|
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice, file e27ce42a-3614-2581-e053-d805fe0acbaa
|
255
|
|
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2, file e27ce426-d04f-2581-e053-d805fe0acbaa
|
238
|
|
Rab11 and phosphoinositides: A synergy of signal transducers in the control of vesicular trafficking, file e27ce42b-aaff-2581-e053-d805fe0acbaa
|
230
|
|
Comparison of 3 Tfr2-deficient murine models suggestsdistinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues, file e27ce426-c1c0-2581-e053-d805fe0acbaa
|
227
|
|
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction., file e27ce426-f7cc-2581-e053-d805fe0acbaa
|
218
|
|
PI3K-C2γ 3 is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling, file e27ce427-b06e-2581-e053-d805fe0acbaa
|
205
|
|
PI3K Signaling in Tissue Hyper-Proliferation: From Overgrowth Syndromes to Kidney Cysts, file e27ce42b-8e2a-2581-e053-d805fe0acbaa
|
177
|
|
Macrophage PI3Kγ drives pancreatic ductal adenocarcinoma progression, file e27ce42a-4721-2581-e053-d805fe0acbaa
|
175
|
|
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits, file e27ce42a-a4b1-2581-e053-d805fe0acbaa
|
174
|
|
Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics, file e27ce42c-ef09-2581-e053-d805fe0acbaa
|
160
|
|
Rule out of acute aortic dissection with plasma matrix metalloproteinase 8 in the emergency department., file e27ce428-4df5-2581-e053-d805fe0acbaa
|
143
|
|
Data demonstrating the anti-oxidant role of hemopexin in the heart, file e27ce42c-15b4-2581-e053-d805fe0acbaa
|
136
|
|
The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC, file e27ce42e-be4c-2581-e053-d805fe0acbaa
|
136
|
|
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis, file e27ce42d-962a-2581-e053-d805fe0acbaa
|
134
|
|
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting, file e27ce42d-10c9-2581-e053-d805fe0acbaa
|
128
|
|
Rho GTPases in intellectual disability: From genetics to therapeutic opportunities, file e27ce42e-8fbe-2581-e053-d805fe0acbaa
|
128
|
|
Hyper-activation of the Rho-GTPase Rac1 via disruption of ArhGAP15 results in reduced architectural and functional complexity, file e27ce42b-983b-2581-e053-d805fe0acbaa
|
125
|
|
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease, file e27ce42d-a215-2581-e053-d805fe0acbaa
|
113
|
|
An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology, file e27ce42e-6a03-2581-e053-d805fe0acbaa
|
108
|
|
Integrin function and regulation in development., file e27ce426-ab61-2581-e053-d805fe0acbaa
|
103
|
|
Functions of PDE3 Isoforms in Cardiac Muscle, file e27ce42e-6a04-2581-e053-d805fe0acbaa
|
101
|
|
How PI3K-derived lipids control cell division, file e27ce42d-8ffb-2581-e053-d805fe0acbaa
|
100
|
|
Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5, file e27ce42e-7efc-2581-e053-d805fe0acbaa
|
100
|
|
Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis, file e27ce42e-be4a-2581-e053-d805fe0acbaa
|
92
|
|
P110γ/δ double-deficiency induces eosinophilia and ige production but protects from ova-induced airway inflammation, file e27ce42e-ac97-2581-e053-d805fe0acbaa
|
88
|
|
The inhibition of phosphoinositide-3 kinases induce resolution of inflammation in a gout model, file e27ce42e-7d5c-2581-e053-d805fe0acbaa
|
84
|
|
PI(3,4)P2 Signaling in Cancer and Metabolism, file e27ce431-277a-2581-e053-d805fe0acbaa
|
79
|
|
Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits, file e27ce433-81bd-2581-e053-d805fe0acbaa
|
58
|
|
Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes, file e27ce433-9456-2581-e053-d805fe0acbaa
|
53
|
|
Chemical oral cancerogenesis is impaired in pi3kγ knockout and kinase-dead mice, file e27ce434-0b95-2581-e053-d805fe0acbaa
|
46
|
|
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function, file e27ce42c-2bcd-2581-e053-d805fe0acbaa
|
44
|
|
Protumor steering of cancer inflammation by p50 nf-kb enhances colorectal cancer progression, file e27ce433-7803-2581-e053-d805fe0acbaa
|
43
|
|
Novel lymphocyte-independent antitumor activity by PD-1 blocking antibody against PD-1+ chemoresistant lung cancer cells, file 68f37efa-f34e-4e08-8b01-b1921586362f
|
35
|
|
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function, file e27ce433-8b6e-2581-e053-d805fe0acbaa
|
34
|
|
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth, file e27ce433-bbd2-2581-e053-d805fe0acbaa
|
33
|
|
Protective Role of the M-Sec-Tunneling Nanotube System in Podocytes, file e27ce431-f6a7-2581-e053-d805fe0acbaa
|
29
|
|
Structural basis of phosphatidylinositol 3-kinase C2α function, file e27ce435-2cf0-2581-e053-d805fe0acbaa
|
23
|
|
Phosphoinositide Conversion Inactivates R-RAS and Drives Metastases in Breast Cancer, file e27ce434-ca8c-2581-e053-d805fe0acbaa
|
22
|
|
Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation, file e27ce432-545c-2581-e053-d805fe0acbaa
|
20
|
|
Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling, file e27ce432-582f-2581-e053-d805fe0acbaa
|
20
|
|
Protumor steering of cancer inflammation by p50 nf-kb enhances colorectal cancer progression, file e27ce42e-7a43-2581-e053-d805fe0acbaa
|
18
|
|
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer, file e27ce432-5373-2581-e053-d805fe0acbaa
|
18
|
|
In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes, file e27ce432-4cba-2581-e053-d805fe0acbaa
|
15
|
|
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis, file e27ce432-453b-2581-e053-d805fe0acbaa
|
10
|
|
Phosphoinositide 3-kinase signalling in the vascular system, file e27ce42d-115c-2581-e053-d805fe0acbaa
|
7
|
|
Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy, file 6a8d7528-0f43-4cee-bbd5-b74defc42c53
|
6
|
|
Targeting the extracellular HSP90 co-chaperone Morgana inhibits cancer cell migration and promotes anti-cancer immunity, file e27ce432-bd55-2581-e053-d805fe0acbaa
|
6
|
|
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma, file a529b480-6b01-4e32-b281-b02bfdda93fc
|
5
|
|
Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma, file 46ef473b-1772-4ecc-a7cd-5c487348f742
|
4
|
|
Cancer: natural-born killers unleashed., file e27ce427-0573-2581-e053-d805fe0acbaa
|
3
|
|
Macrophage PI3Kγ drives pancreatic ductal adenocarcinoma progression, file e27ce42a-2e3e-2581-e053-d805fe0acbaa
|
3
|
|
An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology, file e27ce432-453c-2581-e053-d805fe0acbaa
|
2
|
|
Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation, file e27ce432-4e73-2581-e053-d805fe0acbaa
|
2
|
|
Protumor steering of cancer inflammation by p50 nf-kb enhances colorectal cancer progression, file e27ce432-525a-2581-e053-d805fe0acbaa
|
2
|
|
Class II PI3K Functions in Cell Biology and Disease, file e27ce432-5375-2581-e053-d805fe0acbaa
|
2
|
|
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth, file e27ce432-582b-2581-e053-d805fe0acbaa
|
2
|
|
The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity, file e27ce432-6156-2581-e053-d805fe0acbaa
|
2
|
|
In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes, file e27ce432-9a56-2581-e053-d805fe0acbaa
|
2
|
|
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis, file e27ce434-a36a-2581-e053-d805fe0acbaa
|
2
|
|
Phosphoinositide 3-kinase gamma: kinase-dependent and -independent activities in cardiovascular function and disease, file e27ce426-ae26-2581-e053-d805fe0acbaa
|
1
|
|
The turtle and the rabbit story in a modern (PI3)key, file e27ce42d-aa95-2581-e053-d805fe0acbaa
|
1
|
|
Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes, file e27ce432-4529-2581-e053-d805fe0acbaa
|
1
|
|
Mechanisms underlying the cross-talk between heart and cancer, file e27ce432-c4c6-2581-e053-d805fe0acbaa
|
1
|
|
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload., file e27ce432-e32c-2581-e053-d805fe0acbaa
|
1
|
|
IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload., file e27ce432-f36b-2581-e053-d805fe0acbaa
|
1
|
| Totale |
8.266 |