HIRSCH, Emilio
 Distribuzione geografica
Continente #
NA - Nord America 27.944
EU - Europa 20.056
AS - Asia 5.701
SA - Sud America 113
AF - Africa 99
OC - Oceania 37
Continente sconosciuto - Info sul continente non disponibili 12
Totale 53.962
Nazione #
US - Stati Uniti d'America 27.523
DK - Danimarca 10.113
CN - Cina 3.187
IT - Italia 2.194
DE - Germania 1.618
SG - Singapore 1.330
IE - Irlanda 989
SE - Svezia 973
FR - Francia 900
UA - Ucraina 770
FI - Finlandia 568
GB - Regno Unito 449
PT - Portogallo 417
CA - Canada 396
AT - Austria 374
KR - Corea 369
PL - Polonia 229
JP - Giappone 165
VN - Vietnam 148
BE - Belgio 116
IN - India 110
HK - Hong Kong 105
BR - Brasile 92
SN - Senegal 71
CH - Svizzera 68
NL - Olanda 61
ID - Indonesia 55
PH - Filippine 54
ES - Italia 38
RU - Federazione Russa 34
TW - Taiwan 33
AU - Australia 31
IR - Iran 31
IL - Israele 30
GR - Grecia 28
NO - Norvegia 27
RO - Romania 25
CZ - Repubblica Ceca 23
MX - Messico 19
TR - Turchia 17
TH - Thailandia 15
PK - Pakistan 14
SA - Arabia Saudita 14
EU - Europa 11
AR - Argentina 10
MU - Mauritius 10
BY - Bielorussia 6
LT - Lituania 6
NZ - Nuova Zelanda 6
ZA - Sudafrica 6
AL - Albania 5
HU - Ungheria 5
RS - Serbia 5
MO - Macao, regione amministrativa speciale della Cina 4
NG - Nigeria 4
SI - Slovenia 4
CL - Cile 3
CO - Colombia 3
EG - Egitto 3
HR - Croazia 3
LU - Lussemburgo 3
UY - Uruguay 3
BG - Bulgaria 2
BN - Brunei Darussalam 2
BT - Bhutan 2
BZ - Belize 2
IQ - Iraq 2
JO - Giordania 2
MA - Marocco 2
MY - Malesia 2
PR - Porto Rico 2
PS - Palestinian Territory 2
UG - Uganda 2
A1 - Anonimo 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
CR - Costa Rica 1
CY - Cipro 1
EC - Ecuador 1
GP - Guadalupe 1
IS - Islanda 1
KH - Cambogia 1
LB - Libano 1
LI - Liechtenstein 1
LK - Sri Lanka 1
NP - Nepal 1
PE - Perù 1
RE - Reunion 1
TM - Turkmenistan 1
UZ - Uzbekistan 1
Totale 53.962
Città #
Ann Arbor 11.813
Chandler 2.359
Beijing 1.577
Houston 1.411
Ashburn 1.274
Wilmington 1.189
Singapore 1.082
Dublin 985
Santa Clara 819
Torino 582
Dearborn 541
Jacksonville 490
Fairfield 439
Munich 422
Villeurbanne 376
Vienna 367
Nyköping 319
Princeton 303
Turin 301
Medford 289
Columbus 283
Redwood City 238
Grafing 234
Milan 231
Montréal 210
Fremont 204
Palaiseau 203
Boston 199
Seattle 194
Woodbridge 194
Warsaw 192
Cambridge 142
Guangzhou 140
Shenyang 126
Nanjing 110
Hangzhou 105
Verona 102
Dong Ket 98
Pisa 97
Shanghai 92
Boardman 90
Buffalo 73
Helsinki 73
Toronto 69
Brussels 62
Hefei 59
Los Angeles 55
New York 53
Jakarta 50
Norwalk 47
Rome 46
Falls Church 45
San Diego 45
Kunming 43
Hong Kong 40
Ottawa 39
Washington 38
Manila 37
Paris 37
Tokyo 34
Zhengzhou 33
Des Moines 32
Nürnberg 32
Chengdu 30
Berlin 29
Fortaleza 28
Jinan 28
Xian 28
Chennai 27
Wuhan 27
Seoul 26
Hebei 25
Lachine 25
Nanchang 25
Baltimore 24
Taipei 24
Mountain View 23
Naples 23
Asti 22
Dallas 22
Chongqing 21
Fuzhou 21
Padova 21
Changsha 20
Phoenix 20
Madrid 19
Brno 18
London 18
Shenzhen 18
Athens 17
Duncan 17
Lappeenranta 17
San Mateo 17
Chicago 16
Central 15
Dresden 15
Düsseldorf 15
Napoli 15
Silver Spring 15
Dammam 14
Totale 32.249
Nome #
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth 641
Integrin function and regulation in development. 559
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice 529
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases 525
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress 504
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction. 454
Morgana acts as an oncosuppressor in chronic myeloid leukemia. 449
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2 408
Comparison of 3 Tfr2-deficient murine models suggestsdistinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues 390
Cytokinetic abscission: Phosphoinositides and ESCRTs direct the final cut 366
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting 337
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease 323
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer 321
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis 321
PI3K/AKT signaling pathway and cancer: an updated review. 318
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma 302
Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure 297
Measuring PI3K lipid kinase activity. 276
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. 268
QUINOLIN-4 (1H) -ONE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASES 261
Regulation of expression of PI3Kbeta protein in tumors 256
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. 256
Expression of beta 1 integrin complexes on the surface of unfertilized mouse oocyte. 255
Phosphoinositide 3-kinases as a common platform for multi-hormone signaling 255
Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment 255
The beta 1 integrin distal promoter is developmentally regulated in transgenic mice. 254
Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development. 254
Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema. 253
Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility 253
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 252
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. 251
Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation 250
Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases 250
Magnetically enriched bone marrow-derived macrophages loaded in vitro with iron oxide can migrate to inflammation sites in mice 249
CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells 249
Inhibitors of Phosphatidylinositol 3-Kinases, compositions and uses thereof 247
Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. 247
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma 247
Tumour biology. Weakening link to colorectal cancer? 246
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development 245
Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence 243
Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ. 243
Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes 243
PHOSPHOINOSITIDE 3 KINASE BETA ATTENUATES INFLAMMATION AND FIBROSIS IN A BLEOMYCIN MODEL OF ACUTE LUNG INJURY 241
Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function. 241
Phosphoinositide 3-kinase gamma controls autonomic regulation of the mouse heart through Gi-independent downregulation of cAMP level 240
Role of PI3K gamma in beta-adrenergic stimulation of cardiac contractility and L-type calcium current 240
Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. 240
Gli animali transgenici: frontiera tra la ricerca fondamentale e applicata. 239
Analysis of the murine phosphoinositide 3-kinase gamma gene. 238
Phosphoinositide 3-kinase p110γ in immunity. 238
Morgana is a new oncosuppressor in CML 238
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis 237
Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. 237
Methods to measure the enzymatic activity of PI3Ks. 237
Phosphoinositide 3-kinase gamma gene knockout impairs postischemic neovascularization and endothelial progenitor cell functions 236
Defective Rac-mediated proliferation and survival after targeted mutation of the beta(1) integrin cytodomain 235
A Pro-inflammatory Signature Mediates FGF2-induced Angiogenesis 235
Lipids on the move: phosphoinositide 3-kinases in leukocyte function. 234
Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. 234
CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration. 234
Tissue-specific KO of ECM proteins. 233
A selective role for phosphatidylinositol(3,4,5)trisphosphate in the Gi-dependent activation of platelet Rap1B 232
The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation 232
Myocyte signalling in leucocyte recruitment to the heart. 232
Phosphoinositide 3-kinasegamma (PI3Kgamma) controls L-type calcium current (ICa,L) through its positive modulation of type-3 phosphodiesterase (PDE3) 232
Akt activation by PHLPP1 ablation prevents pathological hypertrophy by promoting angiogenesis. 231
Crossroads of PI3K and Rac pathways 230
Allergic mast cell hyperreactivity needs PI3Kg. 230
Identification of the macromolecular complex responsible for PI3Kgamma-dependent regulation of cAMP levels. 229
Signaling through PI3Kgamma: a common platform for leukocyte, platelet and cardiovascular stress sensing 229
Analysis of regulatory regions of the ciliary neutrophic factor gene in transgenic mice. 229
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility. 229
Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. 228
Tissue-specific KO of ECM proteins 228
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate. 228
Tyrosine kinase Btk regulates E-selectin-mediated integrin activation andneutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways 227
Anchoring proteins as regulators of signaling pathways. 227
Targeting PI3K in Cancer: Any Good News? 227
PI3K keeps the balance between metabolism and cancer. 227
Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis 227
PHOSPHOINOSITIDE-3 KINASE GAMMA ACTIVITY CONTRIBUTES TO BACTERIAL DISSEMINATION DURING ABDOMINAL SEPSIS 227
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. 226
Inhibition of Neutrophil Migration by Hemopexin Leads to IncreasedMortality Due to Sepsis in Mice 226
Determination of positive and negative regulatory elements. 225
Loss of beta1-integrin-deficient cells during the development of endoderm-derived epithelia. 225
Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury 225
Plasma protein haptoglobin modulates renal iron loading 225
The catalytic PI3K isoforms p110{gamma} and p110{delta} contribute to B cell development and maintenance, transformation, and proliferation 225
Tumor biology: mouse models of colon cancer 225
Therapeutic applications of PI3K inhibitors in cardiovascular diseases. 225
The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions. 224
Normal skeletal development of mice lacking matrilin 1: redundant function of matrilins in cartilage? 223
Ciliary neurotrophic factor constitutively expressed in the nervous system of transgenic mice protects embryonic dorsal root ganglion neurons from apoptosis. 223
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion 222
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation 222
The absence of functional PI3Kgamma prevents leukocyte recruitment and amelioratesDSS-induced colitis in mice 222
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis 222
Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling 222
Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. 221
Totale 26.718
Categoria #
all - tutte 124.573
article - articoli 0
book - libri 0
conference - conferenze 1.221
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 125.794


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202012.093 0 0 0 0 0 2.014 1.867 1.494 1.572 1.696 1.658 1.792
2020/20214.432 552 117 197 159 322 206 387 107 586 281 198 1.320
2021/202212.983 1.506 1.457 1.133 1.534 1.040 1.316 1.236 1.151 862 219 680 849
2022/20235.989 605 499 221 644 540 1.377 400 397 672 105 296 233
2023/20242.750 331 431 190 156 178 346 205 217 36 168 178 314
2024/20253.658 155 402 219 661 1.787 434 0 0 0 0 0 0
Totale 56.226