HIRSCH, Emilio
 Distribuzione geografica
Continente #
NA - Nord America 26.443
EU - Europa 19.775
AS - Asia 4.433
AF - Africa 96
SA - Sud America 80
OC - Oceania 29
Continente sconosciuto - Info sul continente non disponibili 12
Totale 50.868
Nazione #
US - Stati Uniti d'America 26.032
DK - Danimarca 10.113
CN - Cina 2.912
IT - Italia 2.040
DE - Germania 1.594
IE - Irlanda 988
SE - Svezia 973
FR - Francia 891
UA - Ucraina 766
FI - Finlandia 523
SG - Singapore 448
GB - Regno Unito 444
PT - Portogallo 416
CA - Canada 388
AT - Austria 372
KR - Corea 366
PL - Polonia 225
VN - Vietnam 148
JP - Giappone 144
BE - Belgio 107
IN - India 105
HK - Hong Kong 88
SN - Senegal 71
CH - Svizzera 64
BR - Brasile 63
PH - Filippine 54
NL - Olanda 49
ES - Italia 36
RU - Federazione Russa 32
TW - Taiwan 31
IL - Israele 29
GR - Grecia 28
IR - Iran 27
NO - Norvegia 27
AU - Australia 24
RO - Romania 24
CZ - Repubblica Ceca 23
MX - Messico 17
TR - Turchia 16
TH - Thailandia 15
SA - Arabia Saudita 14
EU - Europa 11
PK - Pakistan 11
MU - Mauritius 10
AR - Argentina 9
BY - Bielorussia 6
AL - Albania 5
HU - Ungheria 5
ID - Indonesia 5
LT - Lituania 5
NZ - Nuova Zelanda 5
RS - Serbia 5
ZA - Sudafrica 5
MO - Macao, regione amministrativa speciale della Cina 4
NG - Nigeria 4
SI - Slovenia 4
CL - Cile 3
EG - Egitto 3
HR - Croazia 3
LU - Lussemburgo 3
UY - Uruguay 3
BG - Bulgaria 2
BN - Brunei Darussalam 2
BT - Bhutan 2
BZ - Belize 2
IQ - Iraq 2
JO - Giordania 2
MY - Malesia 2
PR - Porto Rico 2
PS - Palestinian Territory 2
UG - Uganda 2
A1 - Anonimo 1
CO - Colombia 1
CR - Costa Rica 1
GP - Guadalupe 1
IS - Islanda 1
KH - Cambogia 1
LB - Libano 1
LI - Liechtenstein 1
LK - Sri Lanka 1
PE - Perù 1
RE - Reunion 1
UZ - Uzbekistan 1
Totale 50.868
Città #
Ann Arbor 11.813
Chandler 2.359
Beijing 1.568
Houston 1.411
Ashburn 1.259
Wilmington 1.189
Dublin 984
Torino 582
Dearborn 541
Jacksonville 490
Fairfield 439
Munich 421
Villeurbanne 376
Vienna 365
Nyköping 319
Princeton 303
Singapore 293
Medford 289
Redwood City 238
Grafing 234
Turin 231
Milan 220
Montréal 210
Fremont 204
Palaiseau 203
Boston 196
Woodbridge 194
Seattle 193
Warsaw 191
Cambridge 141
Shenyang 126
Nanjing 109
Guangzhou 103
Hangzhou 99
Verona 99
Dong Ket 98
Pisa 97
Boardman 90
Shanghai 84
Buffalo 73
Toronto 68
Brussels 62
Hefei 58
New York 53
Los Angeles 49
Norwalk 47
Falls Church 45
San Diego 45
Rome 41
Kunming 40
Washington 38
Manila 37
Ottawa 37
Santa Clara 34
Helsinki 33
Des Moines 32
Nürnberg 32
Paris 32
Tokyo 31
Zhengzhou 30
Chengdu 29
Fortaleza 28
Xian 28
Berlin 27
Chennai 27
Jinan 27
Seoul 26
Hebei 25
Lachine 25
Nanchang 25
Baltimore 24
Taipei 24
Wuhan 24
Hong Kong 23
Mountain View 23
Asti 22
Dallas 22
Phoenix 20
Changsha 19
Brno 18
London 18
Athens 17
Chongqing 17
Duncan 17
Madrid 17
Naples 17
Padova 17
San Mateo 17
Fuzhou 16
Lappeenranta 16
Central 15
Dresden 15
Düsseldorf 15
Napoli 15
Silver Spring 15
Dammam 14
Moncalieri 14
Oslo 14
Shenzhen 14
Bethesda 13
Totale 30.077
Nome #
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth 559
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice 513
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases 512
Integrin function and regulation in development. 495
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress 492
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction. 442
Morgana acts as an oncosuppressor in chronic myeloid leukemia. 432
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2 392
Comparison of 3 Tfr2-deficient murine models suggestsdistinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues 372
Cytokinetic abscission: Phosphoinositides and ESCRTs direct the final cut 346
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting 320
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis 316
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease 312
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer 311
PI3K/AKT signaling pathway and cancer: an updated review. 302
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma 287
Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure 283
Measuring PI3K lipid kinase activity. 266
QUINOLIN-4 (1H) -ONE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASES 253
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. 253
Regulation of expression of PI3Kbeta protein in tumors 251
Expression of beta 1 integrin complexes on the surface of unfertilized mouse oocyte. 250
Phosphoinositide 3-kinases as a common platform for multi-hormone signaling 245
Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility 245
Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development. 244
The beta 1 integrin distal promoter is developmentally regulated in transgenic mice. 243
Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment 243
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 243
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. 242
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. 241
Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases 241
Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema. 241
Tumour biology. Weakening link to colorectal cancer? 239
Magnetically enriched bone marrow-derived macrophages loaded in vitro with iron oxide can migrate to inflammation sites in mice 239
Inhibitors of Phosphatidylinositol 3-Kinases, compositions and uses thereof 238
Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation 238
CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells 237
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma 237
Role of PI3K gamma in beta-adrenergic stimulation of cardiac contractility and L-type calcium current 236
Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function. 235
Gli animali transgenici: frontiera tra la ricerca fondamentale e applicata. 234
Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ. 234
Phosphoinositide 3-kinase gamma controls autonomic regulation of the mouse heart through Gi-independent downregulation of cAMP level 233
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis 233
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development 231
Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. 231
Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. 231
Tissue-specific KO of ECM proteins. 229
Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. 229
CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration. 229
Lipids on the move: phosphoinositide 3-kinases in leukocyte function. 228
Analysis of the murine phosphoinositide 3-kinase gamma gene. 228
Phosphoinositide 3-kinase gamma gene knockout impairs postischemic neovascularization and endothelial progenitor cell functions 228
PHOSPHOINOSITIDE 3 KINASE BETA ATTENUATES INFLAMMATION AND FIBROSIS IN A BLEOMYCIN MODEL OF ACUTE LUNG INJURY 228
Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence 227
Defective Rac-mediated proliferation and survival after targeted mutation of the beta(1) integrin cytodomain 227
Methods to measure the enzymatic activity of PI3Ks. 226
Morgana is a new oncosuppressor in CML 225
A Pro-inflammatory Signature Mediates FGF2-induced Angiogenesis 224
The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation 224
Tissue-specific KO of ECM proteins 224
Tyrosine kinase Btk regulates E-selectin-mediated integrin activation andneutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways 224
Crossroads of PI3K and Rac pathways 223
Phosphoinositide 3-kinasegamma (PI3Kgamma) controls L-type calcium current (ICa,L) through its positive modulation of type-3 phosphodiesterase (PDE3) 223
A selective role for phosphatidylinositol(3,4,5)trisphosphate in the Gi-dependent activation of platelet Rap1B 222
Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. 222
Myocyte signalling in leucocyte recruitment to the heart. 222
Allergic mast cell hyperreactivity needs PI3Kg. 222
Loss of beta1-integrin-deficient cells during the development of endoderm-derived epithelia. 221
Analysis of regulatory regions of the ciliary neutrophic factor gene in transgenic mice. 221
Phosphoinositide 3-kinase p110γ in immunity. 221
Tumor biology: mouse models of colon cancer 221
Identification of the macromolecular complex responsible for PI3Kgamma-dependent regulation of cAMP levels. 220
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility. 219
Determination of positive and negative regulatory elements. 218
Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury 218
Signaling through PI3Kgamma: a common platform for leukocyte, platelet and cardiovascular stress sensing 218
The catalytic PI3K isoforms p110{gamma} and p110{delta} contribute to B cell development and maintenance, transformation, and proliferation 218
Inhibition of Neutrophil Migration by Hemopexin Leads to IncreasedMortality Due to Sepsis in Mice 218
Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling 217
Therapeutic applications of PI3K inhibitors in cardiovascular diseases. 217
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion 216
Targeting PI3K in Cancer: Any Good News? 216
PI3K keeps the balance between metabolism and cancer. 216
Akt activation by PHLPP1 ablation prevents pathological hypertrophy by promoting angiogenesis. 216
Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis 216
PHOSPHOINOSITIDE-3 KINASE GAMMA ACTIVITY CONTRIBUTES TO BACTERIAL DISSEMINATION DURING ABDOMINAL SEPSIS 216
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate. 216
Signal transduction in inflammation. Perspective clues from the leukocyte-endothelium interface 215
Anchoring proteins as regulators of signaling pathways. 215
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation 214
Green fluorescent protein as a reporter of gene expression in transgenic mice. 214
Plasma protein haptoglobin modulates renal iron loading 214
Ciliary neurotrophic factor constitutively expressed in the nervous system of transgenic mice protects embryonic dorsal root ganglion neurons from apoptosis. 214
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization 213
Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. 213
The absence of functional PI3Kgamma prevents leukocyte recruitment and amelioratesDSS-induced colitis in mice 213
PI3K in cancer-stroma interactions: bad in seed and ugly in soil. 213
Peri-implantation lethality in mice lacking the Sm motif-containing protein Lsm4. 212
Targeting phosphoinositide 3-kinase gamma to fight inflammation and more 212
Totale 25.568
Categoria #
all - tutte 112.100
article - articoli 0
book - libri 0
conference - conferenze 1.120
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 113.220


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202014.991 0 0 1.019 561 1.318 2.014 1.867 1.494 1.572 1.696 1.658 1.792
2020/20214.432 552 117 197 159 322 206 387 107 586 281 198 1.320
2021/202212.983 1.506 1.457 1.133 1.534 1.040 1.316 1.236 1.151 862 219 680 849
2022/20235.989 605 499 221 644 540 1.377 400 397 672 105 296 233
2023/20242.750 331 431 190 156 178 346 205 217 36 168 178 314
2024/2025557 155 402 0 0 0 0 0 0 0 0 0 0
Totale 53.125