HIRSCH, Emilio
 Distribuzione geografica
Continente #
NA - Nord America 28.128
EU - Europa 20.560
AS - Asia 6.671
SA - Sud America 393
AF - Africa 110
OC - Oceania 40
Continente sconosciuto - Info sul continente non disponibili 13
Totale 55.915
Nazione #
US - Stati Uniti d'America 27.678
DK - Danimarca 10.113
CN - Cina 3.274
IT - Italia 2.310
SG - Singapore 2.069
DE - Germania 1.776
IE - Irlanda 990
SE - Svezia 973
FR - Francia 908
UA - Ucraina 776
FI - Finlandia 579
AT - Austria 525
GB - Regno Unito 462
PT - Portogallo 417
CA - Canada 408
KR - Corea 370
BR - Brasile 343
PL - Polonia 230
HK - Hong Kong 173
JP - Giappone 168
VN - Vietnam 152
BE - Belgio 119
IN - India 118
NL - Olanda 78
SN - Senegal 71
CH - Svizzera 70
ID - Indonesia 56
PH - Filippine 54
RU - Federazione Russa 42
ES - Italia 39
AU - Australia 34
TW - Taiwan 33
IL - Israele 32
TR - Turchia 32
IR - Iran 31
MX - Messico 30
GR - Grecia 29
NO - Norvegia 28
RO - Romania 25
CZ - Repubblica Ceca 24
AR - Argentina 22
PK - Pakistan 16
SA - Arabia Saudita 15
TH - Thailandia 15
EU - Europa 11
IQ - Iraq 11
MU - Mauritius 10
ZA - Sudafrica 8
AL - Albania 7
EC - Ecuador 7
LT - Lituania 7
BY - Bielorussia 6
JO - Giordania 6
NZ - Nuova Zelanda 6
EG - Egitto 5
HU - Ungheria 5
RS - Serbia 5
UZ - Uzbekistan 5
CL - Cile 4
KZ - Kazakistan 4
LU - Lussemburgo 4
MA - Marocco 4
MO - Macao, regione amministrativa speciale della Cina 4
NG - Nigeria 4
SI - Slovenia 4
UY - Uruguay 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
BD - Bangladesh 3
CO - Colombia 3
DO - Repubblica Dominicana 3
HR - Croazia 3
PE - Perù 3
PS - Palestinian Territory 3
TN - Tunisia 3
AM - Armenia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BN - Brunei Darussalam 2
BO - Bolivia 2
BT - Bhutan 2
BZ - Belize 2
DZ - Algeria 2
KG - Kirghizistan 2
LB - Libano 2
MY - Malesia 2
NP - Nepal 2
PR - Porto Rico 2
UG - Uganda 2
A1 - Anonimo 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
CR - Costa Rica 1
CY - Cipro 1
GP - Guadalupe 1
IS - Islanda 1
JM - Giamaica 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
Totale 55.905
Città #
Ann Arbor 11.813
Chandler 2.359
Beijing 1.578
Houston 1.411
Ashburn 1.284
Wilmington 1.189
Singapore 1.119
Dublin 986
Santa Clara 819
Torino 582
Dearborn 541
Jacksonville 490
Fairfield 439
Vienna 439
Munich 423
Villeurbanne 376
Turin 371
Nyköping 319
Princeton 303
Medford 289
Columbus 283
Redwood City 238
Milan 235
Grafing 234
Montréal 210
Fremont 204
Palaiseau 203
Boston 199
Seattle 194
Woodbridge 194
Warsaw 193
Nuremberg 150
Guangzhou 143
Cambridge 142
Shenyang 126
Nanjing 114
Hangzhou 106
Hong Kong 106
Verona 102
Dong Ket 98
Pisa 97
Shanghai 96
Boardman 90
Helsinki 84
Buffalo 73
Toronto 72
Brussels 64
Los Angeles 62
Hefei 59
New York 53
Jakarta 50
Norwalk 47
Rome 46
Falls Church 45
San Diego 45
Kunming 43
Ottawa 39
Washington 38
Manila 37
Paris 37
Tokyo 35
Des Moines 33
Zhengzhou 33
Chengdu 32
Nürnberg 32
Berlin 29
Chennai 29
Fortaleza 29
Jinan 28
Naples 28
Xian 28
Wuhan 27
Mountain View 26
Seoul 26
Hebei 25
Lachine 25
Nanchang 25
Baltimore 24
Taipei 24
London 23
Asti 22
Dallas 22
Silver Spring 22
Chongqing 21
Fuzhou 21
Padova 21
Phoenix 21
Changsha 20
Düsseldorf 20
Madrid 19
Montreal 19
Tianjin 19
Brno 18
Shenzhen 18
São Paulo 18
Athens 17
Duncan 17
Lappeenranta 17
San Mateo 17
Chicago 16
Totale 32.727
Nome #
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth 695
Integrin function and regulation in development. 612
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases 542
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice 536
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress 523
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction. 464
Morgana acts as an oncosuppressor in chronic myeloid leukemia. 458
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2 416
Comparison of 3 Tfr2-deficient murine models suggestsdistinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues 399
Cytokinetic abscission: Phosphoinositides and ESCRTs direct the final cut 377
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting 343
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease 334
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer 330
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis 330
PI3K/AKT signaling pathway and cancer: an updated review. 325
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma 323
Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure 315
Measuring PI3K lipid kinase activity. 287
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. 278
Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes 271
QUINOLIN-4 (1H) -ONE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASES 267
Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment 262
Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development. 261
Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility 261
Phosphoinositide 3-kinases as a common platform for multi-hormone signaling 260
Regulation of expression of PI3Kbeta protein in tumors 260
Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema. 260
Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases 259
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 259
CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells 258
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. 258
Expression of beta 1 integrin complexes on the surface of unfertilized mouse oocyte. 257
The beta 1 integrin distal promoter is developmentally regulated in transgenic mice. 257
Magnetically enriched bone marrow-derived macrophages loaded in vitro with iron oxide can migrate to inflammation sites in mice 256
Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. 255
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. 254
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma 254
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development 252
Inhibitors of Phosphatidylinositol 3-Kinases, compositions and uses thereof 252
Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation 252
Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ. 251
Tumour biology. Weakening link to colorectal cancer? 250
Phosphoinositide 3-kinase gamma controls autonomic regulation of the mouse heart through Gi-independent downregulation of cAMP level 250
Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence 249
PHOSPHOINOSITIDE 3 KINASE BETA ATTENUATES INFLAMMATION AND FIBROSIS IN A BLEOMYCIN MODEL OF ACUTE LUNG INJURY 248
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis 247
Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function. 246
Analysis of the murine phosphoinositide 3-kinase gamma gene. 245
Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. 245
Methods to measure the enzymatic activity of PI3Ks. 245
A Pro-inflammatory Signature Mediates FGF2-induced Angiogenesis 244
Role of PI3K gamma in beta-adrenergic stimulation of cardiac contractility and L-type calcium current 244
Phosphoinositide 3-kinase gamma gene knockout impairs postischemic neovascularization and endothelial progenitor cell functions 243
Phosphoinositide 3-kinase p110γ in immunity. 243
Morgana is a new oncosuppressor in CML 243
Gli animali transgenici: frontiera tra la ricerca fondamentale e applicata. 242
A selective role for phosphatidylinositol(3,4,5)trisphosphate in the Gi-dependent activation of platelet Rap1B 242
Tissue-specific KO of ECM proteins. 241
Identification of the macromolecular complex responsible for PI3Kgamma-dependent regulation of cAMP levels. 240
The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation 240
Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. 240
Defective Rac-mediated proliferation and survival after targeted mutation of the beta(1) integrin cytodomain 239
Anchoring proteins as regulators of signaling pathways. 239
Myocyte signalling in leucocyte recruitment to the heart. 239
Lipids on the move: phosphoinositide 3-kinases in leukocyte function. 237
Analysis of regulatory regions of the ciliary neutrophic factor gene in transgenic mice. 237
Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. 237
CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration. 237
Phosphoinositide 3-kinasegamma (PI3Kgamma) controls L-type calcium current (ICa,L) through its positive modulation of type-3 phosphodiesterase (PDE3) 237
Signaling through PI3Kgamma: a common platform for leukocyte, platelet and cardiovascular stress sensing 236
PI3K keeps the balance between metabolism and cancer. 236
Akt activation by PHLPP1 ablation prevents pathological hypertrophy by promoting angiogenesis. 236
Allergic mast cell hyperreactivity needs PI3Kg. 236
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility. 235
Crossroads of PI3K and Rac pathways 235
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate. 235
Plasma protein haptoglobin modulates renal iron loading 234
Tyrosine kinase Btk regulates E-selectin-mediated integrin activation andneutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways 234
Targeting PI3K in Cancer: Any Good News? 233
The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions. 232
Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis 232
Inhibition of Neutrophil Migration by Hemopexin Leads to IncreasedMortality Due to Sepsis in Mice 232
Therapeutic applications of PI3K inhibitors in cardiovascular diseases. 232
Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury 231
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. 231
Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. 231
Tissue-specific KO of ECM proteins 231
The absence of functional PI3Kgamma prevents leukocyte recruitment and amelioratesDSS-induced colitis in mice 231
The catalytic PI3K isoforms p110{gamma} and p110{delta} contribute to B cell development and maintenance, transformation, and proliferation 231
Loss of beta1-integrin-deficient cells during the development of endoderm-derived epithelia. 230
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis 230
Determination of positive and negative regulatory elements. 229
Normal skeletal development of mice lacking matrilin 1: redundant function of matrilins in cartilage? 229
Tumor biology: mouse models of colon cancer 229
PHOSPHOINOSITIDE-3 KINASE GAMMA ACTIVITY CONTRIBUTES TO BACTERIAL DISSEMINATION DURING ABDOMINAL SEPSIS 229
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion 227
Leukocyte transmigration is modulated by chemokine-mediated PI3Kgamma-dependent phosphorylation of vimentin 227
MICRO-FLUIDIC DEVICE FOR MEASUREMENTS OF CELL MIGRATION IN RESPONSE TO CHEMICAL STIMULI 227
Dissection of the interplay between class I PI3Ks and Rac signaling in phagocytic functions 227
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation 226
Totale 27.526
Categoria #
all - tutte 135.431
article - articoli 0
book - libri 0
conference - conferenze 1.337
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 136.768


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20206.718 0 0 0 0 0 0 0 0 1.572 1.696 1.658 1.792
2020/20214.432 552 117 197 159 322 206 387 107 586 281 198 1.320
2021/202212.983 1.506 1.457 1.133 1.534 1.040 1.316 1.236 1.151 862 219 680 849
2022/20235.989 605 499 221 644 540 1.377 400 397 672 105 296 233
2023/20242.750 331 431 190 156 178 346 205 217 36 168 178 314
2024/20255.639 155 402 219 661 1.787 542 305 621 947 0 0 0
Totale 58.207