CINECA IRIS Institutional Research Information System

HIRSCH, Emilio
 Distribuzione geografica
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Continente #
NA - Nord America 26.256
EU - Europa 19.624
AS - Asia 3.760
AF - Africa 96
SA - Sud America 56
OC - Oceania 27
Continente sconosciuto - Info sul continente non disponibili 12
Totale 49.831
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Nazione #
US - Stati Uniti d'America 25.850
DK - Danimarca 10.113
CN - Cina 2.675
IT - Italia 1.974
DE - Germania 1.573
IE - Irlanda 985
SE - Svezia 973
FR - Francia 884
UA - Ucraina 765
FI - Finlandia 511
GB - Regno Unito 436
PT - Portogallo 415
CA - Canada 386
AT - Austria 371
KR - Corea 364
PL - Polonia 225
VN - Vietnam 148
JP - Giappone 136
BE - Belgio 104
IN - India 101
HK - Hong Kong 72
SN - Senegal 71
CH - Svizzera 64
SG - Singapore 60
NL - Olanda 45
BR - Brasile 42
PH - Filippine 40
ES - Italia 36
TW - Taiwan 31
RU - Federazione Russa 29
GR - Grecia 28
IL - Israele 27
IR - Iran 27
NO - Norvegia 27
AU - Australia 24
RO - Romania 24
TR - Turchia 16
TH - Thailandia 15
MX - Messico 14
SA - Arabia Saudita 14
EU - Europa 11
MU - Mauritius 10
AR - Argentina 9
PK - Pakistan 9
BY - Bielorussia 6
AL - Albania 5
HU - Ungheria 5
ID - Indonesia 5
LT - Lituania 5
RS - Serbia 5
ZA - Sudafrica 5
CZ - Repubblica Ceca 4
MO - Macao, regione amministrativa speciale della Cina 4
NG - Nigeria 4
SI - Slovenia 4
CL - Cile 3
EG - Egitto 3
HR - Croazia 3
LU - Lussemburgo 3
NZ - Nuova Zelanda 3
BN - Brunei Darussalam 2
BT - Bhutan 2
BZ - Belize 2
IQ - Iraq 2
JO - Giordania 2
MY - Malesia 2
PR - Porto Rico 2
PS - Palestinian Territory 2
UG - Uganda 2
A1 - Anonimo 1
CO - Colombia 1
CR - Costa Rica 1
GP - Guadalupe 1
IS - Islanda 1
KH - Cambogia 1
LB - Libano 1
LI - Liechtenstein 1
LK - Sri Lanka 1
PE - Perù 1
RE - Reunion 1
UZ - Uzbekistan 1
Totale 49.831
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Città #
Ann Arbor 11.813
Chandler 2.359
Beijing 1.566
Houston 1.411
Ashburn 1.244
Wilmington 1.189
Dublin 982
Torino 582
Dearborn 541
Jacksonville 490
Fairfield 439
Munich 415
Villeurbanne 376
Vienna 365
Nyköping 319
Princeton 303
Medford 289
Redwood City 238
Grafing 234
Montréal 210
Turin 210
Milan 209
Fremont 204
Palaiseau 203
Boston 195
Woodbridge 194
Seattle 193
Warsaw 191
Cambridge 139
Guangzhou 101
Hangzhou 99
Dong Ket 98
Pisa 97
Verona 95
Nanjing 94
Boardman 84
Buffalo 73
Shanghai 73
Toronto 68
Brussels 62
Hefei 58
New York 52
Los Angeles 49
Norwalk 47
Falls Church 45
San Diego 45
Rome 40
Washington 38
Manila 37
Ottawa 37
Kunming 36
Des Moines 32
Nürnberg 32
Paris 31
Zhengzhou 30
Xian 28
Berlin 27
Chennai 27
Jinan 27
Seoul 26
Tokyo 26
Hebei 25
Lachine 25
Nanchang 25
Shenyang 25
Baltimore 24
Helsinki 24
Singapore 24
Taipei 24
Wuhan 24
Chengdu 23
Mountain View 23
Asti 22
Dallas 20
Phoenix 19
Athens 17
Duncan 17
London 17
Madrid 17
Padova 17
San Mateo 17
Changsha 16
Chongqing 16
Fuzhou 16
Central 15
Dresden 15
Düsseldorf 15
Lappeenranta 15
Napoli 15
Silver Spring 15
Dammam 14
Hong Kong 14
Moncalieri 14
Oslo 14
Bethesda 13
Central District 13
Detroit 13
Atlanta 12
Chicago 12
Naples 12
Totale 29.515
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Nome #
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice 508
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases 495
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress 483
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth 476
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction. 431
Morgana acts as an oncosuppressor in chronic myeloid leukemia. 423
Integrin function and regulation in development. 421
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2 386
Comparison of 3 Tfr2-deficient murine models suggestsdistinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues 360
Cytokinetic abscission: Phosphoinositides and ESCRTs direct the final cut 341
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting 319
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer 309
Genetic deletion and pharmacological inhibition of PI3K γ reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease 308
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis 306
PI3K/AKT signaling pathway and cancer: an updated review. 298
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma 275
Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure 275
Measuring PI3K lipid kinase activity. 264
QUINOLIN-4 (1H) -ONE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASES 252
Regulation of expression of PI3Kbeta protein in tumors 250
Expression of beta 1 integrin complexes on the surface of unfertilized mouse oocyte. 249
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. 248
Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility 245
Phosphoinositide 3-kinases as a common platform for multi-hormone signaling 244
The beta 1 integrin distal promoter is developmentally regulated in transgenic mice. 241
Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development. 241
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. 240
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 240
Tumour biology. Weakening link to colorectal cancer? 238
Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment 238
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. 238
Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema. 237
CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells 236
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma 236
Role of PI3K gamma in beta-adrenergic stimulation of cardiac contractility and L-type calcium current 235
Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases 235
Magnetically enriched bone marrow-derived macrophages loaded in vitro with iron oxide can migrate to inflammation sites in mice 234
Inhibitors of Phosphatidylinositol 3-Kinases, compositions and uses thereof 234
Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation 234
Gli animali transgenici: frontiera tra la ricerca fondamentale e applicata. 233
Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ. 233
Phosphoinositide 3-kinase gamma controls autonomic regulation of the mouse heart through Gi-independent downregulation of cAMP level 232
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis 231
Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function. 231
Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. 230
Tissue-specific KO of ECM proteins. 229
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development 229
Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. 229
CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration. 228
Lipids on the move: phosphoinositide 3-kinases in leukocyte function. 227
Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. 227
Analysis of the murine phosphoinositide 3-kinase gamma gene. 227
Phosphoinositide 3-kinase gamma gene knockout impairs postischemic neovascularization and endothelial progenitor cell functions 227
Defective Rac-mediated proliferation and survival after targeted mutation of the beta(1) integrin cytodomain 226
Methods to measure the enzymatic activity of PI3Ks. 226
Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence 224
The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation 223
Tyrosine kinase Btk regulates E-selectin-mediated integrin activation andneutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways 223
PHOSPHOINOSITIDE 3 KINASE BETA ATTENUATES INFLAMMATION AND FIBROSIS IN A BLEOMYCIN MODEL OF ACUTE LUNG INJURY 223
Crossroads of PI3K and Rac pathways 223
Tissue-specific KO of ECM proteins 222
Morgana is a new oncosuppressor in CML 222
Loss of beta1-integrin-deficient cells during the development of endoderm-derived epithelia. 221
A Pro-inflammatory Signature Mediates FGF2-induced Angiogenesis 221
Analysis of regulatory regions of the ciliary neutrophic factor gene in transgenic mice. 220
Phosphoinositide 3-kinase p110γ in immunity. 220
Tumor biology: mouse models of colon cancer 220
Identification of the macromolecular complex responsible for PI3Kgamma-dependent regulation of cAMP levels. 219
A selective role for phosphatidylinositol(3,4,5)trisphosphate in the Gi-dependent activation of platelet Rap1B 219
Determination of positive and negative regulatory elements. 218
Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. 218
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility. 218
Myocyte signalling in leucocyte recruitment to the heart. 218
Inhibition of Neutrophil Migration by Hemopexin Leads to IncreasedMortality Due to Sepsis in Mice 218
Phosphoinositide 3-kinasegamma (PI3Kgamma) controls L-type calcium current (ICa,L) through its positive modulation of type-3 phosphodiesterase (PDE3) 218
Targeting PI3K in Cancer: Any Good News? 216
Signal transduction in inflammation. Perspective clues from the leukocyte-endothelium interface 215
Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury 215
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion 215
The catalytic PI3K isoforms p110{gamma} and p110{delta} contribute to B cell development and maintenance, transformation, and proliferation 215
PI3K keeps the balance between metabolism and cancer. 215
Akt activation by PHLPP1 ablation prevents pathological hypertrophy by promoting angiogenesis. 215
Allergic mast cell hyperreactivity needs PI3Kg. 215
PHOSPHOINOSITIDE-3 KINASE GAMMA ACTIVITY CONTRIBUTES TO BACTERIAL DISSEMINATION DURING ABDOMINAL SEPSIS 215
Therapeutic applications of PI3K inhibitors in cardiovascular diseases. 215
Signaling through PI3Kgamma: a common platform for leukocyte, platelet and cardiovascular stress sensing 214
Green fluorescent protein as a reporter of gene expression in transgenic mice. 214
Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis 214
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation 213
Ciliary neurotrophic factor constitutively expressed in the nervous system of transgenic mice protects embryonic dorsal root ganglion neurons from apoptosis. 213
Anchoring proteins as regulators of signaling pathways. 213
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization 212
Plasma protein haptoglobin modulates renal iron loading 212
The absence of functional PI3Kgamma prevents leukocyte recruitment and amelioratesDSS-induced colitis in mice 211
PI3K in cancer-stroma interactions: bad in seed and ugly in soil. 211
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate. 211
Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling 211
Leukocyte transmigration is modulated by chemokine-mediated PI3Kgamma-dependent phosphorylation of vimentin 210
The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. 210
Peri-implantation lethality in mice lacking the Sm motif-containing protein Lsm4. 209
Totale 25.125
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Categoria #
all - tutte 101.412
article - articoli 0
book - libri 0
conference - conferenze 1.017
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 102.429
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019549 0 0 0 0 0 0 0 0 0 0 356 193
2019/202015.679 128 560 1.019 561 1.318 2.014 1.867 1.494 1.572 1.696 1.658 1.792
2020/20214.432 552 117 197 159 322 206 387 107 586 281 198 1.320
2021/202212.983 1.506 1.457 1.133 1.534 1.040 1.316 1.236 1.151 862 219 680 849
2022/20235.989 605 499 221 644 540 1.377 400 397 672 105 296 233
2023/20242.266 331 431 190 156 178 346 205 217 37 168 7 0
Totale 52.084