Lymph node status is the most important prognostic factor for patients with invasive squamous cell carcinoma (SCC) of the vulva. However, few studies have investigated the influence of pathological variables of metastatic groin nodes on survival; the results are not always homogeneous. OBJECTIVE: To investigate the influence of some clinicopathologic variables of lymph node metastases on survival. METHODS: A review of 38 patients with SCC of the vulva and positive groin lymph nodes was performed in order to study the following parameters: diameter of tumor, depth of stromal invasion, number of positive lymph nodes, greatest dimension of metastasis within the lymph node, percentage of lymph node replacement and extracapsular speed. Log rank univariate analysis was performed. RESULTS: The median diameter of the tumors was ...
Prognostic Influence of Metastatic Patterns of Groin Lymph Node Positivity in Squamous Cell Carcinoma of the Vulva
MICHELETTI, Leonardo;MASSOBRIO, Marco
1998-01-01
Abstract
Lymph node status is the most important prognostic factor for patients with invasive squamous cell carcinoma (SCC) of the vulva. However, few studies have investigated the influence of pathological variables of metastatic groin nodes on survival; the results are not always homogeneous. OBJECTIVE: To investigate the influence of some clinicopathologic variables of lymph node metastases on survival. METHODS: A review of 38 patients with SCC of the vulva and positive groin lymph nodes was performed in order to study the following parameters: diameter of tumor, depth of stromal invasion, number of positive lymph nodes, greatest dimension of metastasis within the lymph node, percentage of lymph node replacement and extracapsular speed. Log rank univariate analysis was performed. RESULTS: The median diameter of the tumors was ...
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