Background. ALS is associated with cognitive impairment in 50% of patients, going from frontotemporal dementia (ALS-FTD), to executive cognitive impairment (ALS-ECI), non-executive cognitive impairment (ALS-NECI) and behavioral impairment (ALS-Bi). A protective effect of cognitive reserve has been described in AD and FTD. No data about its role in ALS with comorbid FTD are available. Aim. To assess the impact of cognitive reserve in a population-based series of ALS patients with different degrees of cognitive impairment.
Cognitive Reserve in ALS with Comorbid Frontotemporal Dementia (FTD): A Population-Based Study
Antonio Canosa;MONTUSCHI, ANNA;CALVO, Andrea;MOGLIA, Cristina;LOPIANO, Leonardo;Anna Lo Presti;
2014-01-01
Abstract
Background. ALS is associated with cognitive impairment in 50% of patients, going from frontotemporal dementia (ALS-FTD), to executive cognitive impairment (ALS-ECI), non-executive cognitive impairment (ALS-NECI) and behavioral impairment (ALS-Bi). A protective effect of cognitive reserve has been described in AD and FTD. No data about its role in ALS with comorbid FTD are available. Aim. To assess the impact of cognitive reserve in a population-based series of ALS patients with different degrees of cognitive impairment.
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