The present invention relates to an improved cellulase system, also called cellulosome, derived from a cellulolytic bacterium. The present invention further relates to the use of such improved cellulase system for modifying a lactic acid bacterium so that such recombinant bacterium may degrade cellulose, including crystalline cellulose. More particularly, the invention relates to a recombinant lactic acid bacterium expressing an improved cellulase system and producing lactic acid from cellulosic biomass. The present invention further relates to methods for degrading a cellulosic biomass using said recombinant lactic acid bacterium, and advantageously producing lactic acid.
Recombinant cellulosome complex and uses thereof
MAZZOLI, Roberto;PESSIONE, Enrica;
2013-01-01
Abstract
The present invention relates to an improved cellulase system, also called cellulosome, derived from a cellulolytic bacterium. The present invention further relates to the use of such improved cellulase system for modifying a lactic acid bacterium so that such recombinant bacterium may degrade cellulose, including crystalline cellulose. More particularly, the invention relates to a recombinant lactic acid bacterium expressing an improved cellulase system and producing lactic acid from cellulosic biomass. The present invention further relates to methods for degrading a cellulosic biomass using said recombinant lactic acid bacterium, and advantageously producing lactic acid.
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