The reliabilityof the use of FPTs through the boundaries of an OU process to model interspikes intervals (ISIs) is investigated by means of a new method inspired to an algorithm that solves the inverse FPT proble. The boundary shape corresponding to experimental ISI is determined when the underthreshold membrane potential behavior is modeled via an OU process with parameters estimated from the data. The values are finally compared with the constant value characterizing the model.
On the relationship between interspikes interval distribution and boundary shape in the Ornstein-Uhlenbeck neuronal model
SACERDOTE, Laura Lea;ZUCCA, CRISTINA
2003-01-01
Abstract
The reliabilityof the use of FPTs through the boundaries of an OU process to model interspikes intervals (ISIs) is investigated by means of a new method inspired to an algorithm that solves the inverse FPT proble. The boundary shape corresponding to experimental ISI is determined when the underthreshold membrane potential behavior is modeled via an OU process with parameters estimated from the data. The values are finally compared with the constant value characterizing the model.
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