This patent reports a new, general procedure for the production of N,N-dimethyl-N'-arylureas using S,S-dimethyl dithiocarbonate (DMDTC) as a phosgene substitute. The procedure consists of three steps: i) reaction of DMDTC with dimethylamine to give S-methyl N,N-dimethylthiocarbamates; ii) chlorination to give N,N-dimethylcarbamoyl chlorides; iii) reaction with arylamines. All the products were obtained in high yields and with high purity. To be noted is the complete exploitation of the reagent.

Processo per la preparazione di N,N-dimetil-N'-feniluree

DEGANI, Jacopo;FOCHI, Rita;CADAMURO, Silvano;
2004

Abstract

This patent reports a new, general procedure for the production of N,N-dimethyl-N'-arylureas using S,S-dimethyl dithiocarbonate (DMDTC) as a phosgene substitute. The procedure consists of three steps: i) reaction of DMDTC with dimethylamine to give S-methyl N,N-dimethylthiocarbamates; ii) chlorination to give N,N-dimethylcarbamoyl chlorides; iii) reaction with arylamines. All the products were obtained in high yields and with high purity. To be noted is the complete exploitation of the reagent.
IT MI2004A 002402
OXON ITALIA S.p.A.
S; S-dimethyl dithiocarbonate; phosgene substitute; N; N-dimethyl-N'-arylureas; thiocarbamates; carbamoyl chlorides; carbonylation
G. CARVOLI; I. DEGANI; E. PALLUCCA; R. FOCHI; A. M. SERRI; S. CADAMURO; S. GAZZETTO; M. MIGLIACCIO
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/21232
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