The present invention concerns the use of PI3Kβ protein and/or encoding gene for the screening for substances useful in the treatment of cancers, preferably breast cancers. The present invention also concerns a method for the diagnosis of malignant cell growth comprising the measuring the expression of PI3Kβ gene. The invention concerns also non-human transgenic animals as model study for human pathologies, preferably breast cancer, being transgenic for having altered PI3Kβ and Neu-T expression.

Regulation of expression of PI3Kbeta protein in tumors

HIRSCH, Emilio;CIRAOLO, Elisa;FORNI, Guido;CURCIO, CLAUDIA
2008

Abstract

The present invention concerns the use of PI3Kβ protein and/or encoding gene for the screening for substances useful in the treatment of cancers, preferably breast cancers. The present invention also concerns a method for the diagnosis of malignant cell growth comprising the measuring the expression of PI3Kβ gene. The invention concerns also non-human transgenic animals as model study for human pathologies, preferably breast cancer, being transgenic for having altered PI3Kβ and Neu-T expression.
WO/2008/099280
Università degli Studi di Torino
http://www.wipo.int/pctdb/en/wo.jsp?IA=IB2008000382&WO=WO2008%2F099280&DISPLAY=STATUS
breast cancer
Emilio Hirsch; Elisa Ciraolo; Guido Forni; Claudia Curcio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/30005
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