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EnglishIntroduction: Intervertebral disks (ID) can exhibit normal aging changes and degenerative alterations leading to disk extrusion into the spinal canal. Materials and Methods: The authors report the histological features of n. 42 canine spinal surgery specimens comparing the observations between spinal level and breed - chondrodystrophoid (CD) and non chondrodystrophoid (NCD) dogs - by means of the Fisher test. Results: N.22 ID of CD and n. 20 ID of NCD, aging from 3 to12 years old, were evaluated. N. 34 samples were collected in thoracic/lumbar spine, and n. 8 in cervical spine. N. 40 samples were composed mainly by nucleus pulposus; two specimens showed lamellar structures of anulus fibrosus or cartilaginous laminae. Chondroid clusters in degenerate matrix occurred frequently (72.7% of CD e 45 % dei NCD). Chondroid metaplasia was detected in 80.5% of cases; it was significantly more frequent in CD (94.7%), but it was also present in 64.7% of NCD. Calcium deposits were observed in 100% of CD (80% I NCD). Granulation tissue and neovascularisation were detected in 71.43% of cases. In contrast with the literature (Hansen, 1952) the most interesting features were chondroid metaplasia and calcium deposits in NCD. Conclusion: A breed predisposition could induce the chondroid metaplasia, but probably a multifactorial aetiology induces disk degeneration. Further investigations are in progress in order to verify this hypothesis.
INTERVERTEBRAL DISKS DEGENERATION: PRELIMINARY STUDIES ON PATHOLOGICAL FEATURES OF 42 SURGICAL SPECIMENS / Valenza F.; Capucchio M.T.; Amedeo S.; Sammartano F.; Mioletti S.; Valazza A.. - In: JOURNAL OF COMPARATIVE PATHOLOGY. - ISSN 0021-9975. - 143:4(2010), pp. 318-318. ((Intervento presentato al convegno 28th Meeting of the ESVP, tenutosi a Belgrade nel 8-11 september 2010.
| Titolo: | INTERVERTEBRAL DISKS DEGENERATION: PRELIMINARY STUDIES ON PATHOLOGICAL FEATURES OF 42 SURGICAL SPECIMENS | |
| Autori Riconosciuti: | ||
| Autori: | Valenza F.; Capucchio M.T.; Amedeo S.; Sammartano F.; Mioletti S.; Valazza A. | |
| Data di pubblicazione: | 2010 | |
| Abstract: | Introduction: Intervertebral disks (ID) can exhibit normal aging changes and degenerative alterations leading to disk extrusion into the spinal canal. Materials and Methods: The authors report the histological features of n. 42 canine spinal surgery specimens comparing the observations between spinal level and breed - chondrodystrophoid (CD) and non chondrodystrophoid (NCD) dogs - by means of the Fisher test. Results: N.22 ID of CD and n. 20 ID of NCD, aging from 3 to12 years old, were evaluated. N. 34 samples were collected in thoracic/lumbar spine, and n. 8 in cervical spine. N. 40 samples were composed mainly by nucleus pulposus; two specimens showed lamellar structures of anulus fibrosus or cartilaginous laminae. Chondroid clusters in degenerate matrix occurred frequently (72.7% of CD e 45 % dei NCD). Chondroid metaplasia was detected in 80.5% of cases; it was significantly more frequent in CD (94.7%), but it was also present in 64.7% of NCD. Calcium deposits were observed in 100% of CD (80% I NCD). Granulation tissue and neovascularisation were detected in 71.43% of cases. In contrast with the literature (Hansen, 1952) the most interesting features were chondroid metaplasia and calcium deposits in NCD. Conclusion: A breed predisposition could induce the chondroid metaplasia, but probably a multifactorial aetiology induces disk degeneration. Further investigations are in progress in order to verify this hypothesis. | |
| Volume: | 143 | |
| Fascicolo: | 4 | |
| Pagina iniziale: | 318 | |
| Pagina finale: | 318 | |
| Nome del convegno: | 28th Meeting of the ESVP, | |
| Luogo del convegno: | Belgrade | |
| Anno del convegno: | 8-11 september 2010 | |
| ISBN: | 9788691387501 | |
| Rivista: | JOURNAL OF COMPARATIVE PATHOLOGY | |
| Appare nelle tipologie: | 04E-Meeting abstract in rivista |
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