PERRELLI, ANDREA

PERRELLI, ANDREA  

SCIENZE CLINICHE E BIOLOGICHE  

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Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications 2018 Trapani, Eliana; Antognelli, Cinzia; Goitre, Luca; Perrelli, Andrea; Sarri, Sara; Barrera, Giuseppina; Talesa, Vincenzo; Trabalzini, Lorenza; Retta, Saverio Francesco
Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases 2018 Perrelli, Andrea; Goitre, Luca; Salzano, Anna Maria; Moglia, Andrea; Scaloni, Andrea; Retta, Saverio Francesco
Data in support of sustained upregulation of adaptive redox homeostasis mechanisms caused by KRIT1 loss-of-function 2018 Antognelli, Cinzia; Trapani, Eliana; Delle Monache, Simona; Perrelli, Andrea; Fornelli, Claudia; Retta, Francesca; Cassoni, Paola; Talesa, Vincenzo Nicola; Retta, Saverio Francesco*
Dicarbonyl stress and s-glutathionylation in cerebrovascular diseases: A focus on cerebral cavernous malformations 2020 Antognelli C.; Perrelli A.; Armeni T.; Talesa V.N.; Retta S.F.
Fluorescence Analysis of Reactive Oxygen Species (ROS) in Cellular Models of Cerebral Cavernous Malformation Disease 2020 Perrelli A.; Retta S.F.
From Genes and Mechanisms to Molecular-Targeted Therapies: The Long Climb to the Cure of Cerebral Cavernous Malformation (CCM) Disease 2020 Retta S.F.; Perrelli A.; Trabalzini L.; Finetti F.
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations 2018 Fornelli, Claudia; Trapani, Eliana; Mastrocola, Raffaella; Perrelli, Andrea; Benedetti, Valerio; Zotta, Alessia; Costantino, Giulia; Geddo, Federica; Boda, Enrica; Biasi, Fiorella; Goitre, Luca; Retta, Saverio Francesco
KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction 2019 Vieceli Dalla Sega F.; Mastrocola R.; Aquila G.; Fortini F.; Fornelli C.; Zotta A.; Cento A.S.; Perrelli A.; Boda E.; Pannuti A.; Marchi S.; Pinton P.; Ferrari R.; Rizzo P.; Retta S.F.
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 2019 Trapani, E; Antognelli, C; Delle Monache, S; Perrelli, A; Fornelli, C; Benedetti, V; Sarri, S; Costantino, G; Geddo, F; Zotta, A; Goitre, L; Retta, SF
KRIT1 Loss-Of-Function Associated with Cerebral Cavernous Malformation Disease Leads to Enhanced S-Glutathionylation of Distinct Structural and Regulatory Proteins 2019 Cianfruglia, Laura; Perrelli, Andrea; Fornelli, Claudia; Magini, Alessandro; Gorbi, Stefania; Salzano, Anna Maria; Antognelli, Cinzia; Retta, Francesca; Benedetti, Valerio; Cassoni, Paola; Emiliani, Carla; Principato, Giovanni; Scaloni, Andrea; Armeni, Tatiana; Retta, Saverio Francesco
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease 2018 Antognelli, Cinzia*; Trapani, Eliana; Delle Monache, Simona; Perrelli, Andrea; Daga, Martina; Pizzimenti, Stefania; Barrera, Giuseppina; Cassoni, Paola; Angelucci, Adriano; Trabalzini, Lorenza; Talesa, Vincenzo Nicola; Goitre, Luca; Retta, Saverio Francesco
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 2018 Perrelli, Andrea; Trapani, Eliana; Antognelli, Cinzia; Monache, Simona Delle; Fornelli, Claudia; Benedetti, Valerio; Costantino, Giulia; Geddo, Federica; Zotta, Alessia; Sarri, Sara; Bratti, Giovanna; Goitre, Luca; Retta, Saverio Francesco
KRIT1/CCM1 loss-of-function affects sphingolipid metabolism inducing hepatosteatosis and predisposing to liver fibrosis and insulin-resistance 2019 Mastrocola, R; Cento, AS; Fornelli, C; Zotta, A; Perrelli, A; Retta, SF
KRIT1/CCM1 loss-of-function impairs advanced glycation endproducts receptors and detoxification and worsens fructose diet-induced hepatic dysmetabolism 2019 Mastrocola, R; Cento, AS; Fornelli, C; Zotta, A; Perrelli, A; Retta, SF
KRIT1/CCM1 Loss-of-function Mutations Impair Anti-glycative and Anti-oxidant Systems Worsening High Fructose Diet-induced Hepatic Dismetabolism 2019 Mastrocola, R; Fornelli, C; Cento, A; Perrelli, A; Zotta, A; Retta, SF
Multifunctional platinum@bsa-rapamycin nanocarriers for combinatorial therapy of cerebral cavernous malformation disease 2019 Perrelli, A; De Luca, E; Pedone, D; Moglianetti, M; Fornelli, C; Zotta, A; Pulcini, D; Pompa, PP; Retta, SF
Multifunctional Platinum@BSA-Rapamycin Nanocarriers for the Combinatorial Therapy of Cerebral Cavernous Malformation 2018 De Luca, Elisa; Pedone, Deborah; Moglianetti, Mauro; Pulcini, Daniele; Perrelli, Andrea; Retta, Saverio Francesco; Pompa, Pier Paolo
Next-Generation Sequencing Advances the Genetic Diagnosis of Cerebral Cavernous Malformation (CCM) 2022 Benedetti, Valerio; Canzoneri, Rosalia; Perrelli, Andrea; Arduino, Carlo; Zonta, Andrea; Brusco, Alfredo; Retta, Saverio Francesco
Polymorphisms in genes related to oxidative stress and inflammation: Emerging links with the pathogenesis and severity of Cerebral Cavernous Malformation disease 2021 Perrelli, Andrea; Retta, Saverio Francesco
Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease 2020 Goitre L.; Fornelli C.; Zotta A.; Perrelli A.; Retta S.F.