PICCININI, Marco
 Distribuzione geografica
Continente #
NA - Nord America 3.917
EU - Europa 2.476
AS - Asia 1.326
AF - Africa 29
OC - Oceania 15
SA - Sud America 12
Continente sconosciuto - Info sul continente non disponibili 2
Totale 7.777
Nazione #
US - Stati Uniti d'America 3.847
CN - Cina 578
IT - Italia 504
SE - Svezia 345
SG - Singapore 341
IE - Irlanda 296
DE - Germania 265
UA - Ucraina 225
FR - Francia 199
FI - Finlandia 182
GB - Regno Unito 157
KR - Corea 138
AT - Austria 132
IN - India 79
CA - Canada 68
PL - Polonia 58
VN - Vietnam 50
JP - Giappone 34
BE - Belgio 33
ID - Indonesia 17
AU - Australia 15
IR - Iran 15
NL - Olanda 15
SN - Senegal 14
ES - Italia 13
HK - Hong Kong 13
UZ - Uzbekistan 13
TW - Taiwan 10
PK - Pakistan 8
BR - Brasile 7
CZ - Repubblica Ceca 6
MY - Malesia 6
SA - Arabia Saudita 6
TR - Turchia 6
ZA - Sudafrica 6
CH - Svizzera 5
DK - Danimarca 5
GR - Grecia 5
IL - Israele 5
RU - Federazione Russa 5
BG - Bulgaria 4
EG - Egitto 4
HR - Croazia 4
CI - Costa d'Avorio 3
IQ - Iraq 3
RO - Romania 3
RS - Serbia 3
AR - Argentina 2
CL - Cile 2
EU - Europa 2
GE - Georgia 2
HU - Ungheria 2
KG - Kirghizistan 2
MK - Macedonia 2
MT - Malta 2
NO - Norvegia 2
BZ - Belize 1
CO - Colombia 1
EE - Estonia 1
IS - Islanda 1
LV - Lettonia 1
MU - Mauritius 1
MX - Messico 1
PT - Portogallo 1
TG - Togo 1
Totale 7.777
Città #
Chandler 545
Beijing 362
Santa Clara 335
Singapore 299
Dublin 295
Jacksonville 188
Ann Arbor 181
Nyköping 146
Torino 144
Dearborn 135
Vienna 131
Houston 130
Ashburn 106
Medford 103
Villeurbanne 103
Woodbridge 96
Princeton 92
Fremont 89
Columbus 85
Fairfield 74
Wilmington 70
Milan 55
Warsaw 53
Boston 42
Boardman 36
New York 36
Seattle 36
Redwood City 34
Washington 31
Cambridge 30
Mumbai 30
Pisa 30
Brussels 29
Dong Ket 28
Turin 28
Guangzhou 27
Toronto 24
Ottawa 19
Verona 19
Helsinki 17
Jakarta 17
Los Angeles 13
Viterbo 13
Falls Church 12
Norwalk 12
Hefei 11
Lachine 11
Nanjing 11
Shanghai 10
Detroit 9
Mountain View 9
Taipei 9
Zhengzhou 8
Chengdu 7
Kunming 7
Munich 7
Nürnberg 7
Riverside 7
Shenyang 7
Düsseldorf 6
Edinburgh 6
Epsom 6
Hangzhou 6
La Jolla 6
London 6
Paris 6
Piemonte 6
Sherwood Park 6
Bari 5
Dammam 5
Durban 5
Hebei 5
Leinì 5
Otemae 5
Redmond 5
Rome 5
Tokyo 5
Changsha 4
Frankfurt am Main 4
Hong Kong 4
Jinan 4
Montreal 4
Sassari 4
Sesto Fiorentino 4
West Jordan 4
Wuhan 4
Arlington 3
Auburn Hills 3
Baotou 3
Basel 3
Berlin 3
Bologna 3
Brussel 3
Changchun 3
Como 3
Copenhagen 3
Durham 3
Ellicott City 3
Fazal 3
Igusa 3
Totale 4.677
Nome #
PROCEEDINGS OF THE MERCK & ELSEVIER YOUNG CHEMISTSSYMPOSIUM 299
TDP-43 Redistribution Is an Early Event in Sporadic Amyotrophic Lateral Sclerosis 285
Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27KIP1 as a consequence of c-Abl inhibition 263
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds 164
Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation 162
N-Acetyl-3-aminopyrazoles block the non canonical NF-kB cascade by selectively inhibiting NIK 129
Characterization of the chymotriptic activity of the 26 S protease from bovine brain. 123
Increased cytoplasmic mislocalization of TAR DNA binding protein 43 (TDP-43) in circulating lymphomonocytes of ALS patients recapitulates the major dysfunction featuring motor neurons in the disease. 123
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade 120
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase (hDHODH) inhibitors 119
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors 118
IκB kinase β is required for activation of NF-κB and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells. 117
A defective L_MAG (large myelin-associated glycoprotein) is responsible for an adult-onset autosomal dominant orthochromatic leukodystrophy 116
The expression pattern of TAR DNA-binding protein 43 (TDP-43) in peripheral blood mononuclear cells (PBMC) in individuals affected by amyotrophific lateral sclerosis (ALS) and their healthy relatives 115
Acid soluble, short chain esterified and free carnitine in the liver, heart, muscle and brain of pre and post hatched chicks. 115
TOWARD A BIOISOSTERIC ALKAEST – APPLICATION TO THE BIOISOSTERIC MODULATION OF IMD-0354 110
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 106
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety 105
Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of niemannpick disease type A 104
Affinity purification and characterization of protein gene product 9.5 (PGP9.5) from retina. 103
Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations 103
Nitrooxyacyl Derivatives of Salicylic Acid: Aspirin-Like Molecules that Covalently Inactivate Cyclooxygenase-1 103
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentaatomic Heterocycles 102
Towards a Bioisosteric Alkaest: application to the bioisosteric modulation of IMD-0354 100
Myelin is involved in Niemann-Pick disease 98
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by combination of in-silico ligand/structural pharmacophore models and scaffold hopping bioisosteric approaches 98
Detection of a Proteasome in Pneumocystis carinii and its Modulation by Specific Proteasome Inhibitors 95
Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders 94
Myelin involvement in Niemann-Pick disease type A 93
TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis 93
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase inhibitors 93
Dysfunctions in N_CAM and unexpected accumulation of PSA_NCAM in brain of Autosomal dominant adult onset leukodystrophy (ADLD) 92
An approach to the timing of altered localization of TDP-43 in ALS motor neurons during disease progression 92
Myelin-associated glycoprotein is altered in a familial late-onset orthochromatic leukodystrophy 91
Modulazione della glicolisi in cellule endoteliali umane sottoposte ad elevate concentrazioni di glucosio in vitro. 91
Myelin-associated glycoprotein is altered in a familial orthochromatic leukodystrophy 89
Modulazione della glicolisi in cellule endoteliali umane sottoposte ad elevate concentrazioni di glucosio in vitro. 87
Discovery of new NIK inhibitors by Structure-Based Drug Design 87
In obese individuals dexfenfluramine corrects molecular derangements reflecting insulin resistance 85
The insulin signal and its effects on the pyruvate dehydrogenase complex in circulating lymphocytes of obese children. 84
The behaviour of pyruvate dehydrogenase in circulating lymphocytes from diabetic children 84
Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors 84
The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function 83
Pregnancy induces molecular alterations reflecting impaired insulin control over glucose oxidative pathways that only in women with a family history for type 2 diabetes last beyond pregnancy 83
Characterization of the 20S proteasome in human glioblastomas 82
Altered sphingolipid metabolism in acidic sphingomyelinase knocout mice, an animal model for Niemann-Pick disease type A 82
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors 82
Insulin modulation of pyruvate dehydrogenase in human circulating lymphocytes. 81
Down-regulation of pyruvate dehydrogenase phosphatase in obese subjects is a defect that signals insulin resistance 81
Myelin-associated glycoprotein is defective in a familial orthochromatic leukodystrophy 80
Biomarker for Frontotemporal Lobar Degeneration (FTLD) with TDP-43 Pathology: the Circulating Lymphocytes 80
Expression pattern of the 20S proteasome subunits following T cell activation 79
The molecular basis of the hypomyelination characterizing the brains of sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A 76
Modulation of glycolysis by high glucose in cultured human endothelial cells. 76
Effect of sulfonylurea agents on pyruvate dehydrogenase activity in circulating lymphocytes from patients with non-insulin-dependent diabetes mellitus (NIDDM). 75
Distribution of protein gene product 9.5 (PGP 9.5) in the vertebrate retina: evidence that immunoreactivity is restricted to mammalian horizontal and ganglion cells. 74
In CD28-costimulated human naïve CD4(+) T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms 74
Derangements of pyruvate dehydrogenase in circulating lymphocytes of NIDDM patients and their healthy offspring. 71
Novel dysfunctions at the origin of hypomyelination, a feature of Niemann Pick type A 71
Myelin-associated glycoprotein is defective in a familail orthochromatic leukodystrophy 70
Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. 70
Levels of carnitine and glycogen in rabbit tissues during development. 70
Alterations of protein and lipid patterns in brain white matter of ASMKO mice, the animal model of Niemann-Pick disease type A 69
Reduced expression of proteins characterizing myelin sheaths in brain of acid sphingomyelinase-deficinet mice, the animal model of Niemann-Pick disease type A 65
null 65
Enhanced blood insulin overcomes pyruvate dehydrogenase derangements that reflect systemic insulin resistance in obese adolescents. 62
G proteins and regulation of pyruvate dehydrogenase activity by insulin in human circulating lymphocytes. 62
Type I collagen limits VEGFR-2 signaling by a SHP2 protein-tyrosine phosphatase-dependent mechanism 1 61
Pyruvate dehydrogenase activation by insulin in human circulating lymphocytes and the possible pathway involved. 61
Insulin resistance in obese subjects and newly diagnosed NIDDM patients and derangements of pyruvate dehydrogenase in their circulating lymphocytes 59
Proteasomes are a target of the anti-tumour drug vinblastine 56
Modulation of glycolysis by high glucose in cultured human endothelial cells. 56
Proteasomes as drug targets. 55
Purificazione e caratterizzazione di proteasomi renali umani 55
Structural and functional properties of proteasomes purified from the human kidney 54
Multidiscliplinary approach to cause and pathogenesis of an adult onset autosomal dominant orthochromatic leukodystrophy 53
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 50
Structural and functional characterization of 20S and 26S proteasomes from bovine brain. 49
Proteins targeted by ubiquitin and the ubiquitin-proteasome system in malignant gliomas 48
Immunoproteasome Activity in the Nervous System 47
Molecular effects of sulphonylurea agents in circulating lymphocytes of patients with non-insulin-dependent diabetes mellitus. 47
Primary structure and oxygen-binding properties of the hemoglobin from the lesser hedgehog tenrec (Echinops telfairi, Zalambdodonta). Evidence for phylogenetic isolation. 46
The Ubiquitin Proteasome System in The Pathobiology of Human Gliomas (Chapter 36) 46
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 45
The human 26S proteasome is a target of antiretroviral agents. 44
New human dihydroorotate dehydrogenase inhibitors able to restore myeloid differentiation in AML 44
N-CAM Dysfunction and Unexpected Accumulation of PSA-NCAM in Brain of Adult-Onset Autosomal-Dominant Leukodystrophy. 43
Interferon-gamma-inducible subunits are incorporated in human brain 20S proteasome. 42
The Ubiquitin Proteasome System in The Pathobiology of Human Gliomas in 41
Toward a Bioisosteric Alkahest: Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 40
Primary structure and oxygen-binding properties of the hemoglobin from guanaco (Lama guanaco, Tylopoda). 30
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib 21
Targeting Plasmodium falciparum dihydroorotate dehydrogenase: design, synthesis, co-crystallization and biological evaluation of new 3-hydroxypyrazole scaffold-based inhibitors 16
Targeting Plasmodium falciparum dihydroorotate dehydrogenase: design, synthesis, co-crystallization and biological evaluation of new 3-hydroxypyrazole scaffold-based inhibitors 16
Totale 8.022
Categoria #
all - tutte 24.177
article - articoli 0
book - libri 0
conference - conferenze 10.742
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.919


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020617 0 0 0 0 0 171 113 42 74 109 72 36
2020/2021755 106 67 52 40 71 33 65 26 124 55 42 74
2021/2022965 26 16 52 57 32 49 55 36 19 100 311 212
2022/20231.490 163 164 30 168 125 383 108 91 132 34 63 29
2023/2024598 88 143 53 33 23 76 6 16 2 40 30 88
2024/20251.092 26 173 70 252 480 91 0 0 0 0 0 0
Totale 8.022