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EnglishCombined multichannel intraluminal impedance and pH-monitoring (MII/pH) is a new technique identifying refluxes irrespective of acidity and detecting their duration, proximal extent and pH. These features are important when studying gastroesophageal-reflux disease (GERD) in infants, in which weakly acid refluxes are prevalent. Clinical application of MII/pH is uncommon yet, owing to lack of reference values and difficult interpretation of the variables obtained. Aim of the present study was to investigate the relationship between MII-pH results and clinical outcome on a sample of GERD infants. Conclusions: MII-pH in first months of life could be useful to identify patients with high risk of presenting GER symptoms for more than 1 year. BEI is a pH independent variable with a significant relationship with symptoms duration. Our data highlight the clinical relevance of MII/pH-detected weakly acidic refluxes in GERD infant.
| Titolo: | Gastroesophageal reflux disease in infant: relationship between Multichannel Intraluminal Impedance-pH monitoring and clinical outcome | |
| Autori Riconosciuti: | ||
| Autori: | Cresi F; Locatelli E; Marinaccio C; Grasso G; Castagno E; Silvestro L. | |
| Data di pubblicazione: | 2010 | |
| Abstract: | Combined multichannel intraluminal impedance and pH-monitoring (MII/pH) is a new technique identifying refluxes irrespective of acidity and detecting their duration, proximal extent and pH. These features are important when studying gastroesophageal-reflux disease (GERD) in infants, in which weakly acid refluxes are prevalent. Clinical application of MII/pH is uncommon yet, owing to lack of reference values and difficult interpretation of the variables obtained. Aim of the present study was to investigate the relationship between MII-pH results and clinical outcome on a sample of GERD infants. Conclusions: MII-pH in first months of life could be useful to identify patients with high risk of presenting GER symptoms for more than 1 year. BEI is a pH independent variable with a significant relationship with symptoms duration. Our data highlight the clinical relevance of MII/pH-detected weakly acidic refluxes in GERD infant. | |
| Volume: | 14 | |
| Pagina iniziale: | 142 | |
| Pagina finale: | 142 | |
| Nome del convegno: | 3rd Congress of the European Academy of Paediatric Societes (EAPS) | |
| Luogo del convegno: | Copenhagen | |
| Anno del convegno: | 23 - 26 ottobre 2010 | |
| Parole Chiave: | Gastroesophageal reflux disease; MII/pH; infants | |
| Rivista: | PEDIATRIC RESEARCH | |
| Appare nelle tipologie: | 04E-Meeting abstract in rivista |
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