Application of the arachno™ technology inside Educational fields: the introduction of parallel synthesis concepts inside an undergraduated lab

The parallel synthesis is a powerful tool in the hand in Drug Design, usually applied to the obtainment of a library of molecules during hit-to- lead processes. Its application, because the expensive technology involved, is restricted to high technological research laboratories. arachno TM (www.arachnoscience.com) is a revolutionary, easy-to- get low cost technology that allows the performance of up to six organic experiment at the same time. 1 Being inexpensive, arachno TM can be easily introduced at educational level. In this occasion is presented its application in the parallel preparation of a library of Aspirin analogues. Inside a full day labtime, each student will be able to obtain six different Aspirin amide analogues, each compound in isolated pure form. This exercise will offer the possibility to practically introduce to the class, beside the parallel synthesis itself, also concepts of practical organic synthesis, TLC, 1 H-, 13 C-NMR and MS, being all the obtained compounds fully characterized.