CINECA IRIS Institutional Research Information System

ROCCO, Flavio
 Distribuzione geografica
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Continente #
NA - Nord America 4.115
EU - Europa 2.883
AS - Asia 1.419
AF - Africa 22
Continente sconosciuto - Info sul continente non disponibili 12
SA - Sud America 10
OC - Oceania 7
Totale 8.468
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Nazione #
US - Stati Uniti d'America 4.089
CN - Cina 531
DE - Germania 428
IT - Italia 410
IE - Irlanda 405
SE - Svezia 404
UA - Ucraina 292
SG - Singapore 278
FI - Finlandia 258
KR - Corea 218
FR - Francia 204
VN - Vietnam 184
JP - Giappone 146
DK - Danimarca 120
GB - Regno Unito 109
PL - Polonia 107
AT - Austria 75
RU - Federazione Russa 31
CA - Canada 25
SN - Senegal 19
IN - India 18
ID - Indonesia 13
EU - Europa 11
BE - Belgio 9
GR - Grecia 8
IR - Iran 7
UZ - Uzbekistan 7
AU - Australia 6
HK - Hong Kong 6
NL - Olanda 6
BR - Brasile 5
CO - Colombia 5
RO - Romania 4
LT - Lituania 3
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
CZ - Repubblica Ceca 2
ES - Italia 2
IL - Israele 2
MA - Marocco 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
DZ - Algeria 1
EE - Estonia 1
JO - Giordania 1
KH - Cambogia 1
MX - Messico 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PT - Portogallo 1
TH - Thailandia 1
Totale 8.468
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Città #
Chandler 449
Dublin 404
Santa Clara 401
Beijing 373
Jacksonville 293
Ann Arbor 277
Singapore 200
Fairfield 167
Dearborn 155
Dong Ket 153
Houston 151
Ashburn 142
Princeton 140
Torino 122
Wilmington 116
Columbus 113
Frankfurt am Main 109
Villeurbanne 109
Woodbridge 107
Warsaw 106
Medford 101
Boston 85
Seattle 75
Vienna 75
Nyköping 58
Cambridge 56
Pisa 52
Boardman 44
Munich 34
Milan 30
Fremont 29
Norwalk 28
Guangzhou 25
Nanjing 22
Hefei 21
San Mateo 19
New York 18
Düsseldorf 17
Falls Church 17
Jakarta 13
Kunming 12
Verona 12
Helsinki 11
Toronto 11
San Diego 10
Washington 10
Shanghai 9
Turin 9
Zhengzhou 9
Brussels 8
Gif-sur-yvette 8
Phoenix 8
Redwood City 8
Lachine 7
Tulsa 7
Hong Kong 6
Ardabil 5
Hangzhou 5
London 5
Loreto 5
Nanchang 5
Ottawa 5
Fuzhou 4
Ginebra 4
Mountain View 4
Palermo 4
Recife 4
Shenzhen 4
West Jordan 4
Brisbane 3
Des Moines 3
Detroit 3
Hebei 3
Iesi 3
Kharkiv 3
Moscow 3
Mumbai 3
Nuremberg 3
Philadelphia 3
Pune 3
Redmond 3
Shenyang 3
Sydney 3
Al Ain 2
Aulla 2
Baotou 2
Catania 2
Changsha 2
Chicago 2
Chongqing 2
Collegno 2
Grafing 2
Grevenbroich 2
Jinan 2
Leawood 2
Ludhiana 2
Monmouth Junction 2
Nürnberg 2
Perugia 2
Scottsdale 2
Totale 5.185
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Nome #
Carbammati lipidici di farmaci antitumorali. 448
Antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase 219
1,5-Benzodiazepines XIV. Synthesis of new substituted 9H-bis[1,2,4]triazolo[4,3-a:3’,4’-d] [1,5]benzodiazepines and relate compounds endowed with in vitro cytotoxic properties 172
Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems. 162
Amphiphilic polyaspartamide copolymer-based micelles for rivastigmine delivery to neuronal cells 156
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 154
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 141
Inulin-based polymer coated SPIONs as potential drug delivery systems for targeted cancer therapy 127
Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases 124
Use of squalenic acid for the formulation of an active principle in nanoparticle state 121
Nonpolymeric nanoassemblies for ocular administration of acyclovir: pharmacokinetic evaluation in rabbits 120
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 118
Characterization of lipophilic gemcitabine prodrug-liposomal membrane interaction by differential scanning calorimetry 108
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 105
Strategies to Obtain Encapsulation and Controlled Release of Pentamidine in Mesoporous Silica Nanoparticles 105
Structure and reactivity of the dammarenyl cation: configurational transmission in triterpene synthesis 104
Interaction of lipophilic gemcitabine prodrugs with biomembrane models studied by Langmuir-Blodgett technique 103
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 95
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 90
Interaction of acyclovir and its squalenoyl-acyclovir prodrug with DMPC in monolayers at the air/water interface 89
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 87
The metabolic fate of the anti-parkinsonian drug budipine in rats. 86
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 83
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 82
The in vitro metabolism of 1,3-thiazolidine derivatives of theophylline: a study on structure-metabolism correlation. 82
A convenient synthesis of [3-3H]squalene and [3-3H]-2,3-oxidosqualene. 81
Metabolism of 4-(3-cyclohexylpropionyl)-1-(2-ethoxyphenyl)- piperazine by rat liver microsomes. 80
Gemcitabine derivatives nanoparticles 79
Antifungal and cytotoxic activity of two inhibitors of 2,3-oxidosqualene cyclase. 79
Synthesis of HEI analogues of the C-20 carbocation forming during lanosterol biosynthesis, as hypocholesterolemics. 79
Synthesis of new gemcitabine prodrugs for liposome and nanoparticle encapsulation 79
Total synthesis of the hypocholesterolemic and antifungal drug 10-azasqualene 2,3-epoxide, the first non-cyclized analogue of the C-8 carbonium ion formed during squalene epoxide cyclization. 79
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 78
Nonpolymeric nanoparticles for ocular administration of acyclovir 78
A preliminary pharmacokinetic study of docetaxel, carboplatin and concurrent radiotherapy for regionally advanced squamous cell carcinoma of the head and neck 78
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 77
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 76
Nanoparticle derivatives of gemcitabine 75
Antifungal and cytotoxic activity of two inhibitors of 2,3-oxidosqualene cyclase 75
Synthesis of [3-3H]squalene and [3-3H]-2,3-oxidosqualene. 74
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane and 1,3-dithiane derivatives of theophylline: a structure-metabolism correlation study. 74
Synthesis of tritium-labelled 19-azasqualene 2,3-epoxide and derivatives, as probes to study their hypocholesterolemic activity. 74
Synthesis and biological activity of aryldithio and maleimido squalene derivatives as new irreversible inhibitors of squalene 2,3-oxide-lanosterol cyclase. 74
New difluoro-2'-deoxycytidine derivatives, useful as anticancer and antiviral agents, contain residue that promotes formation of nanoparticles and increases stability in serum 73
Antifungal and cytotoxic activiti of two inhibitors of 2,3-oxidosqualene cyclase 72
(E) and (Z)-29-methylidene-2,3-oxidosqualene as stereospecific mechanism-based inhibitors of 2,3-oxidosqualene cyclase. 70
Systematic analysis of yeast strains with possible defects in lipid metabolism 69
Synthesis, characterization and transfection activity of new saturated and unsaturated cationic lipids 69
Biocompatible micelles based on amphiphilic polyaspartamide-squalene derivatives as potential colloidal drug carriers. 68
How radical prostatectomy procedures have changed over the last 10 years in Italy: a comparative analysis based on more than 1500 patients participating in the MIRROR-SIU/LUNA and the Pros-IT CNR study 67
Antitumor activity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs 66
Gemcitabine derivatives nanoparticles 66
In vivo antitumoral activity of liposomes containing 4-(N)-stearoylgemcitabine 66
Gemcitabine derivatives nanoparticles 65
1H-NMR and 13C-NMR studies for the assignment of the structure of (6E)-10-azasqualene 2,3-epoxide and (6Z)-10-azasqualene 2,3-epoxide and their correlation with hypocholesterolemic and antifungal activity. 65
Studio del metabolismo del nuovo analgesico “D-16120” con microsomi di fegato di ratto. 65
Rational inhibition of sterol biosynthesis: new time-dependent inhibitors of 2,3-oxidosqualene cyclase. 65
Incorporation of lipophilic gemcitabine prodrugs in liposomes 65
Nanoparticles of Gemcitabine derivatives 64
Preparation, characterization, cytotoxicity and pharmacokinetcs of liposomes containing lipophilic gemcitabine prodrugs 63
Cyanoacrylate nanospheres and nanocapsules containing lipophilic prodrugs of gemcitabine 63
Caratterizzazione e studio dell’attività di una nuova classe di lipidi cationici. 63
Synthesis and inhibition of cholesterol biosynthesis by azasqualene alcohol and derivatives. 63
In vitro metabolism of 7-(1,3-thiazolidin-2ylmethyl)theophylline: the metabolic fate of the 1,3-thiazolidine ring. 63
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 63
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 63
New difluoro-2'-deoxycytidine derivatives, useful as anticancer and antiviral agents, contain residue that promotes formation of nanoparticles and increases stability in serum 62
Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes. 62
In vitro stability of lipophilic gemcitabine prodrugs 62
Gemcitabine derivatives nanoparticles 61
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 60
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 60
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole. 59
Synthesis of vinyl sulfide derivatives of oxidosqualene, as potent inhibitors of 2,3-oxidosqualene cyclase. 59
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 58
Gemcitabine derivatives nanoparticles 58
Synthesis, antitumor activity and biodistribution of squalenoyl-cytarabine nanoparticles. 57
Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase 57
Cytotoxicity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs 56
Calorimetric evidence of the interaction of a lipophilic conjugate of cytarabine with biomembrane models. 56
Conjugation of Acyclovir with squalene as a tool to enhance its interaction with biomembrane models: a differential scanning calorimetry study. 56
Biocompatible micelles based on squalene portions linked to pegylated polyaspartamide as potential colloidal drug carriers 56
Nanoparticules des derivés de la gemcitabine 56
Absorption of omega-3 fatty acids by biomembrane models studied by differential scanning calorimetry 55
Enhancenent of gemcitabine affinity for biomembrane models by conjugation with squalene 54
New pyrrolidinones with in anticonvulsant activity: studies of cytotoxics on pharmacologicals 53
Sintesi di E e Z-29-metilidino-2,3-ossidosqualene derivati, inibitori irreversibili della ossidosqualene ciclasi. 53
Feniltio e metiltio dieni coniugati, inibitori delle ossidosqualene e squalene-hopene ciclasi. 51
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase. 51
Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules 50
Squalenoyl nanomedicines as potential therapeutics 49
Conjugation of squalene to acyclovir improves the interaction for biomembrane models 49
Nanoaggregati di squalenoil-citarabina: sistemi colloidali innovativi per la terapia antitumorale. 49
Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules 48
Evaluation of cytotoxic activity of new GABA mimetic drugs 48
Conformational features of 4-(N)-squalenoyl-gemcitabine in solution: a combined NMR and molecular dynamics investigation 48
Evaluation of analgesic and anti-inflammatory activity of novel β-lactam monocyclic compounds. 47
Enhancement of gemcitabine affinity for biomembranes by conjugation with squalene: Differential scanning calorimetry and Langmuir-Blodgett studies using biomembrane models 46
Sulfide derivatives of oxidosqualene inhibitors of 2,3-oxidosqualene and squalene-hopene cyclase as antifungals or hypocholesterolemics. 46
In vivo metabolism of the anti-inflammatory agent 2-(ethylpyridin-2-yl)benzimidazole. 46
Totale 8.024
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Categoria #
all - tutte 26.552
article - articoli 0
book - libri 0
conference - conferenze 9.850
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.402
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020692 0 0 0 0 0 0 166 86 179 101 90 70
2020/20211.008 118 40 64 46 84 54 89 24 106 62 93 228
2021/20221.093 27 25 25 86 56 39 95 85 26 90 249 290
2022/20231.373 164 66 23 131 144 435 132 69 130 11 51 17
2023/2024533 81 118 33 26 25 58 8 30 3 21 35 95
2024/2025922 11 63 34 155 607 50 2 0 0 0 0 0
Totale 8.831