ROCCO, Flavio
 Distribuzione geografica
Continente #
NA - Nord America 3.429
EU - Europa 2.829
AS - Asia 1.110
AF - Africa 20
Continente sconosciuto - Info sul continente non disponibili 12
SA - Sud America 9
OC - Oceania 7
Totale 7.416
Nazione #
US - Stati Uniti d'America 3.406
CN - Cina 516
IE - Irlanda 405
SE - Svezia 404
IT - Italia 399
DE - Germania 392
UA - Ucraina 292
FI - Finlandia 257
KR - Corea 217
FR - Francia 204
VN - Vietnam 184
JP - Giappone 146
DK - Danimarca 120
GB - Regno Unito 108
PL - Polonia 106
AT - Austria 75
RU - Federazione Russa 31
CA - Canada 22
SN - Senegal 19
IN - India 15
EU - Europa 11
SG - Singapore 10
BE - Belgio 9
GR - Grecia 8
IR - Iran 7
UZ - Uzbekistan 7
AU - Australia 6
NL - Olanda 6
BR - Brasile 5
CO - Colombia 4
RO - Romania 4
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
CZ - Repubblica Ceca 2
ES - Italia 2
IL - Israele 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
DZ - Algeria 1
JO - Giordania 1
MX - Messico 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
Totale 7.416
Città #
Chandler 449
Dublin 404
Beijing 373
Jacksonville 293
Ann Arbor 277
Fairfield 167
Dearborn 155
Dong Ket 153
Houston 151
Princeton 140
Ashburn 130
Torino 122
Wilmington 116
Villeurbanne 109
Woodbridge 107
Warsaw 106
Medford 101
Boston 85
Frankfurt am Main 80
Vienna 75
Seattle 74
Nyköping 58
Cambridge 56
Pisa 52
Boardman 44
Fremont 29
Milan 29
Munich 29
Norwalk 28
Nanjing 22
Hefei 21
San Mateo 19
Guangzhou 18
New York 18
Düsseldorf 17
Falls Church 17
Kunming 12
Verona 12
Helsinki 10
San Diego 10
Washington 10
Shanghai 9
Toronto 9
Zhengzhou 9
Brussels 8
Gif-sur-yvette 8
Phoenix 8
Redwood City 8
Lachine 7
Tulsa 7
Turin 6
Ardabil 5
Hangzhou 5
Loreto 5
Nanchang 5
Fuzhou 4
Ginebra 4
London 4
Mountain View 4
Ottawa 4
Palermo 4
Recife 4
Shenzhen 4
West Jordan 4
Brisbane 3
Des Moines 3
Detroit 3
Hebei 3
Iesi 3
Kharkiv 3
Moscow 3
Philadelphia 3
Pune 3
Redmond 3
Shenyang 3
Sydney 3
Al Ain 2
Aulla 2
Baotou 2
Catania 2
Changsha 2
Chicago 2
Chongqing 2
Collegno 2
Grafing 2
Grevenbroich 2
Jinan 2
Leawood 2
Ludhiana 2
Monmouth Junction 2
Nürnberg 2
Perugia 2
Scottsdale 2
Singapore 2
University Park 2
Weimar 2
Algés 1
Amman 1
Amsterdam 1
Ancona 1
Totale 4.393
Nome #
Carbammati lipidici di farmaci antitumorali. 412
Antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase 205
1,5-Benzodiazepines XIV. Synthesis of new substituted 9H-bis[1,2,4]triazolo[4,3-a:3’,4’-d] [1,5]benzodiazepines and relate compounds endowed with in vitro cytotoxic properties 157
Amphiphilic polyaspartamide copolymer-based micelles for rivastigmine delivery to neuronal cells 145
Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems. 145
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 141
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 134
Inulin-based polymer coated SPIONs as potential drug delivery systems for targeted cancer therapy 118
Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases 115
Use of squalenic acid for the formulation of an active principle in nanoparticle state 114
Nonpolymeric nanoassemblies for ocular administration of acyclovir: pharmacokinetic evaluation in rabbits 112
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 110
Characterization of lipophilic gemcitabine prodrug-liposomal membrane interaction by differential scanning calorimetry 100
Structure and reactivity of the dammarenyl cation: configurational transmission in triterpene synthesis 96
Interaction of lipophilic gemcitabine prodrugs with biomembrane models studied by Langmuir-Blodgett technique 95
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 95
Strategies to Obtain Encapsulation and Controlled Release of Pentamidine in Mesoporous Silica Nanoparticles 94
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 87
Interaction of acyclovir and its squalenoyl-acyclovir prodrug with DMPC in monolayers at the air/water interface 82
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 79
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 76
Gemcitabine derivatives nanoparticles 73
The metabolic fate of the anti-parkinsonian drug budipine in rats. 73
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 73
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 73
Total synthesis of the hypocholesterolemic and antifungal drug 10-azasqualene 2,3-epoxide, the first non-cyclized analogue of the C-8 carbonium ion formed during squalene epoxide cyclization. 72
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 71
Antifungal and cytotoxic activity of two inhibitors of 2,3-oxidosqualene cyclase. 71
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 70
Synthesis of HEI analogues of the C-20 carbocation forming during lanosterol biosynthesis, as hypocholesterolemics. 70
Nanoparticle derivatives of gemcitabine 69
Nonpolymeric nanoparticles for ocular administration of acyclovir 68
Metabolism of 4-(3-cyclohexylpropionyl)-1-(2-ethoxyphenyl)- piperazine by rat liver microsomes. 68
Synthesis of [3-3H]squalene and [3-3H]-2,3-oxidosqualene. 67
Synthesis of tritium-labelled 19-azasqualene 2,3-epoxide and derivatives, as probes to study their hypocholesterolemic activity. 67
The in vitro metabolism of 1,3-thiazolidine derivatives of theophylline: a study on structure-metabolism correlation. 67
A convenient synthesis of [3-3H]squalene and [3-3H]-2,3-oxidosqualene. 66
New difluoro-2'-deoxycytidine derivatives, useful as anticancer and antiviral agents, contain residue that promotes formation of nanoparticles and increases stability in serum 65
Synthesis and biological activity of aryldithio and maleimido squalene derivatives as new irreversible inhibitors of squalene 2,3-oxide-lanosterol cyclase. 65
Antifungal and cytotoxic activiti of two inhibitors of 2,3-oxidosqualene cyclase 65
Antifungal and cytotoxic activity of two inhibitors of 2,3-oxidosqualene cyclase 65
Synthesis of new gemcitabine prodrugs for liposome and nanoparticle encapsulation 63
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 62
Systematic analysis of yeast strains with possible defects in lipid metabolism 61
Synthesis, characterization and transfection activity of new saturated and unsaturated cationic lipids 61
Biocompatible micelles based on amphiphilic polyaspartamide-squalene derivatives as potential colloidal drug carriers. 61
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane and 1,3-dithiane derivatives of theophylline: a structure-metabolism correlation study. 61
(E) and (Z)-29-methylidene-2,3-oxidosqualene as stereospecific mechanism-based inhibitors of 2,3-oxidosqualene cyclase. 60
A preliminary pharmacokinetic study of docetaxel, carboplatin and concurrent radiotherapy for regionally advanced squamous cell carcinoma of the head and neck 60
Gemcitabine derivatives nanoparticles 59
Gemcitabine derivatives nanoparticles 59
Rational inhibition of sterol biosynthesis: new time-dependent inhibitors of 2,3-oxidosqualene cyclase. 59
Studio del metabolismo del nuovo analgesico “D-16120” con microsomi di fegato di ratto. 57
Nanoparticles of Gemcitabine derivatives 57
How radical prostatectomy procedures have changed over the last 10 years in Italy: a comparative analysis based on more than 1500 patients participating in the MIRROR-SIU/LUNA and the Pros-IT CNR study 57
Cyanoacrylate nanospheres and nanocapsules containing lipophilic prodrugs of gemcitabine 56
Incorporation of lipophilic gemcitabine prodrugs in liposomes 56
New difluoro-2'-deoxycytidine derivatives, useful as anticancer and antiviral agents, contain residue that promotes formation of nanoparticles and increases stability in serum 55
Synthesis and inhibition of cholesterol biosynthesis by azasqualene alcohol and derivatives. 55
1H-NMR and 13C-NMR studies for the assignment of the structure of (6E)-10-azasqualene 2,3-epoxide and (6Z)-10-azasqualene 2,3-epoxide and their correlation with hypocholesterolemic and antifungal activity. 55
In vitro stability of lipophilic gemcitabine prodrugs 55
In vivo antitumoral activity of liposomes containing 4-(N)-stearoylgemcitabine 55
Caratterizzazione e studio dell’attività di una nuova classe di lipidi cationici. 54
Gemcitabine derivatives nanoparticles 54
Antitumor activity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs 53
Preparation, characterization, cytotoxicity and pharmacokinetcs of liposomes containing lipophilic gemcitabine prodrugs 53
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 53
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 52
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 52
Gemcitabine derivatives nanoparticles 51
Synthesis of vinyl sulfide derivatives of oxidosqualene, as potent inhibitors of 2,3-oxidosqualene cyclase. 51
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 50
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 49
Synthesis, antitumor activity and biodistribution of squalenoyl-cytarabine nanoparticles. 49
In vitro metabolism of 7-(1,3-thiazolidin-2ylmethyl)theophylline: the metabolic fate of the 1,3-thiazolidine ring. 49
Conjugation of Acyclovir with squalene as a tool to enhance its interaction with biomembrane models: a differential scanning calorimetry study. 49
Nanoparticules des derivés de la gemcitabine 49
Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase 48
Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes. 47
New pyrrolidinones with in anticonvulsant activity: studies of cytotoxics on pharmacologicals 47
Calorimetric evidence of the interaction of a lipophilic conjugate of cytarabine with biomembrane models. 47
Sintesi di E e Z-29-metilidino-2,3-ossidosqualene derivati, inibitori irreversibili della ossidosqualene ciclasi. 47
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole. 46
Enhancenent of gemcitabine affinity for biomembrane models by conjugation with squalene 45
Feniltio e metiltio dieni coniugati, inibitori delle ossidosqualene e squalene-hopene ciclasi. 44
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase. 44
Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules 43
Absorption of omega-3 fatty acids by biomembrane models studied by differential scanning calorimetry 43
Squalenoyl nanomedicines as potential therapeutics 42
Conjugation of squalene to acyclovir improves the interaction for biomembrane models 42
Evaluation of analgesic and anti-inflammatory activity of novel β-lactam monocyclic compounds. 42
Cytotoxicity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs 42
Nanoaggregati di squalenoil-citarabina: sistemi colloidali innovativi per la terapia antitumorale. 42
Evaluation of cytotoxic activity of new GABA mimetic drugs 42
Conformational features of 4-(N)-squalenoyl-gemcitabine in solution: a combined NMR and molecular dynamics investigation 42
Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules 41
Biocompatible micelles based on squalene portions linked to pegylated polyaspartamide as potential colloidal drug carriers 41
Nanoparticle derivatives of gemcitabine 41
Enhancement of gemcitabine affinity for biomembranes by conjugation with squalene: Differential scanning calorimetry and Langmuir-Blodgett studies using biomembrane models 40
Sulfide derivatives of oxidosqualene inhibitors of 2,3-oxidosqualene and squalene-hopene cyclase as antifungals or hypocholesterolemics. 40
Totale 7.080
Categoria #
all - tutte 20.441
article - articoli 0
book - libri 0
conference - conferenze 7.534
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.975


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019278 0 0 0 0 0 0 0 0 0 0 196 82
2019/20201.335 44 48 124 142 88 197 166 86 179 101 90 70
2020/20211.008 118 40 64 46 84 54 89 24 106 62 93 228
2021/20221.093 27 25 25 86 56 39 95 85 26 90 249 290
2022/20231.373 164 66 23 131 144 435 132 69 130 11 51 17
2023/2024403 81 118 33 26 25 58 8 30 3 21 0 0
Totale 7.779