CINECA IRIS Institutional Research Information System

BALLIANO, Gianni
 Distribuzione geografica
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Continente #
NA - Nord America 4.458
EU - Europa 2.939
AS - Asia 1.941
AF - Africa 86
SA - Sud America 68
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 3
Totale 9.507
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Nazione #
US - Stati Uniti d'America 4.394
CN - Cina 765
SG - Singapore 512
SE - Svezia 508
IE - Irlanda 472
DE - Germania 356
IT - Italia 310
FI - Finlandia 294
KR - Corea 278
FR - Francia 235
UA - Ucraina 231
AT - Austria 139
GB - Regno Unito 139
PL - Polonia 139
JP - Giappone 135
VN - Vietnam 131
SN - Senegal 79
CA - Canada 60
BR - Brasile 56
IN - India 49
RU - Federazione Russa 31
BE - Belgio 24
HK - Hong Kong 19
NL - Olanda 18
ID - Indonesia 13
EU - Europa 12
TW - Taiwan 9
UZ - Uzbekistan 7
CH - Svizzera 6
DK - Danimarca 6
PH - Filippine 6
SK - Slovacchia (Repubblica Slovacca) 6
GR - Grecia 5
CO - Colombia 4
ES - Italia 4
AR - Argentina 3
AU - Australia 3
BD - Bangladesh 3
IR - Iran 3
PT - Portogallo 3
SC - Seychelles 3
BY - Bielorussia 2
CZ - Repubblica Ceca 2
EC - Ecuador 2
IL - Israele 2
MD - Moldavia 2
NO - Norvegia 2
PK - Pakistan 2
TR - Turchia 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
CL - Cile 1
CR - Costa Rica 1
DZ - Algeria 1
GT - Guatemala 1
JO - Giordania 1
KG - Kirghizistan 1
LT - Lituania 1
LV - Lettonia 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
MU - Mauritius 1
MX - Messico 1
PA - Panama 1
PY - Paraguay 1
RO - Romania 1
RS - Serbia 1
TN - Tunisia 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 9.507
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Città #
Chandler 682
Beijing 519
Dublin 471
Santa Clara 363
Ann Arbor 280
Singapore 246
Jacksonville 223
Villeurbanne 158
Princeton 150
Medford 148
Warsaw 138
Vienna 136
Dearborn 132
Houston 130
Columbus 123
Nyköping 112
Fairfield 111
Dong Ket 107
Ashburn 105
Torino 80
Wilmington 79
Woodbridge 69
Boston 65
Boardman 60
Fremont 51
New York 46
Seattle 46
Guangzhou 44
Cambridge 41
Munich 41
Milan 33
Ottawa 32
Redwood City 31
Düsseldorf 25
Brussels 24
Hangzhou 24
Norwalk 20
Pisa 20
Helsinki 18
Washington 18
Des Moines 17
Nanjing 17
Verona 17
Falls Church 15
Toronto 15
Hefei 14
Braunschweig 13
Jakarta 13
Kunming 13
Mumbai 12
Shanghai 12
Hong Kong 11
Los Angeles 11
Moscow 11
Nanchang 11
Fuzhou 9
Lachine 9
Mountain View 9
Rome 9
Hebei 8
Pune 8
Bagnacavallo 7
Falkenstein 7
Tulsa 7
Zhengzhou 7
Bratislava 6
Buffalo 6
Hanover 6
Musashino 6
San Diego 6
Tokyo 6
Changsha 5
Copenhagen 5
Nuremberg 5
Philadelphia 5
Pittsburgh 5
Redmond 5
Amsterdam 4
Bonn 4
Changchun 4
Chengdu 4
Delhi 4
Gwangjin-gu 4
Indianapolis 4
Wuxi 4
Chiyoda-ku 3
Heidelberg 3
Iesi 3
Kumar 3
La Terrasse 3
Naaldwijk 3
Napoli 3
Palermo 3
San Jose 3
San Mateo 3
Shenzhen 3
Strasbourg 3
São Paulo 3
Taipei 3
Turin 3
Totale 5.626
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Nome #
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae 211
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 199
Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors. 195
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 157
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 148
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 145
Aminopropylindenes derived from Grundmann’s ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 142
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 128
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 120
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 113
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 108
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 106
4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase 103
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 102
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 97
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 97
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors 94
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 93
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis. 92
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 92
Azasqualeni N-ossidi e bis-azasqualeni, inibitori dell'enzima squalene epossido ciclasi. 91
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 90
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 89
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 89
POLICOSANOLI DA PULA DI RISO 88
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae. 86
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors. 86
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 85
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 85
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 85
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 84
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 84
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 83
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 83
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 83
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors 83
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase. 83
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. 82
2,3-Oxidosqualene cyclase and squalene epoxidase as target enzymes for the development of new sterol biosynthesis inhibitors 82
Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts 82
Characterization of C-4 demethylation complex of cholesterol biosynthesis 81
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 80
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. 80
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 80
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 80
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 80
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 79
3-carboxy-4-nitrophenyl-dithio-1,1'-2-trisnorsqualene: a site directed inactivator of yeast oxidosqualene cyclase 78
2,3-oxidosqualene cyclase from yeast: a target enzyme for drug discovery. 77
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 77
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 77
Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from a downstream 3-ketoreductase activity (Erg27) in the yeast ergosterol biosynthetic pathway 77
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 76
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 75
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 74
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 74
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 74
Thiol-modifying Inhibitors for Understanding Squalene Cyclase Function. Eur. J. Biochem. (2002) 269, 2108-2116. 73
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 73
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 73
Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives. 73
Thiol-modifying agents as tools for understanding the function of squalene cyclase 73
The 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity in yeast 72
Systematic analysis of yeast strains with possible defects in lipid metabolism 71
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase. 71
Direzionamento di citotossine con anticorpi monoclonali per la terapia del cancro 70
Interaction of Steroid-3-Keto Reductase and Oxidosqualene Cyclase, Two Key Enzymes in the Ergosterol Biosynthetic Pathway 70
Evidence of the existence of an essential thiol group within the active site of oxidosqualene cyclase from Saccharomyces cerevisiae 70
Comparison of the mechanism of yeast oxidosqualene cyclase and bacterial squalene cyclase by using rationally designed inhibitors. 69
Novel Squalene-Hopene Cyclase Inhibitors derived from Hydroxycoumarins and Hydroxyacetophenones 68
Umbelliferone Aminoalkyl Derivatives, a New Class of Squalene-Hopene Cyclase Inhibitors 68
The Interaction of 3-Keto Reductase and Oxidosqualene Cyclase, Two Key Enzymes in the Ergosterol Biosynthetic Pathway 68
Comparative properties of N-ethoxycarbonyl-D-phenylalanyl-L-prolyl-alpha-azalysine p-nitrophenyl ester and N-ethoxycarbonyl-D-phenylalanyl-alpha-azaprolyl-L-lysine p-nitrophenyl ester as subsrates of serine proteinases 68
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 67
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 67
Mutation analysis of the yeast 3-ketoreductase (Erg27p) and the effects on ergosterol biosynthesis 66
Total synthesis and inhibition of sterol biosynthesis by 10-azasqualene 2,3-epoxide, a high-energy intermediate analogue 66
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis, 65
Active site titration of bovine beta-trypsin by N alpha-(N,N-dimethylcarbamoyl)-alpha-aza-lysine p-nitrophenyl ester: kinetic and crystallographic analysis 65
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 65
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 65
Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae. 65
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 64
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 63
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 63
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 63
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole. 62
Sintesi ed attività biologica di azasqualeni, bis-azasqualeni e derivati. 62
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 62
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 60
Protein-protein interactions among ergosterol biosynthesis enzymes Erg7p/Erg27p and two-hybrid interactions involving Are1p and Are2p 60
Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase 60
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 59
Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study 59
Time-dependent inhibition of oxidosqualene cyclase by aza derivatives of squalene oxide. 57
Squalene- and nonsqualene-like thiol modifying agents as tools for understanding the function of squalene-hopene cyclase 57
Inhibition of sterol biosynthesis by an aza analogue of 2,3-oxidosqualene. 56
The squalene 2,3-epoxide cyclase as a model for the development of new drugs 56
Totale 8.414
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Categoria #
all - tutte 33.430
article - articoli 0
book - libri 0
conference - conferenze 14.299
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.729
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020266 0 0 0 0 0 0 0 0 0 111 107 48
2020/20211.050 142 48 51 59 118 55 53 35 146 65 102 176
2021/20221.147 17 28 55 59 62 48 61 64 51 69 284 349
2022/20231.849 225 142 27 200 194 500 170 107 150 10 97 27
2023/2024683 108 145 52 33 33 81 11 48 0 20 31 121
2024/20251.316 13 79 43 194 580 59 35 122 190 1 0 0
Totale 9.889