CINECA IRIS Institutional Research Information System

BALLIANO, Gianni
 Distribuzione geografica
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Continente #
NA - Nord America 4.440
EU - Europa 2.885
AS - Asia 1.721
AF - Africa 83
Continente sconosciuto - Info sul continente non disponibili 12
SA - Sud America 10
OC - Oceania 3
Totale 9.154
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Nazione #
US - Stati Uniti d'America 4.381
CN - Cina 757
SE - Svezia 508
IE - Irlanda 472
DE - Germania 343
SG - Singapore 325
IT - Italia 306
FI - Finlandia 281
KR - Corea 278
FR - Francia 233
UA - Ucraina 230
PL - Polonia 139
GB - Regno Unito 138
AT - Austria 134
JP - Giappone 133
VN - Vietnam 128
SN - Senegal 79
CA - Canada 56
IN - India 49
RU - Federazione Russa 29
BE - Belgio 24
NL - Olanda 15
ID - Indonesia 13
EU - Europa 12
HK - Hong Kong 11
BR - Brasile 6
SK - Slovacchia (Repubblica Slovacca) 6
TW - Taiwan 6
UZ - Uzbekistan 6
GR - Grecia 5
PH - Filippine 5
CH - Svizzera 4
DK - Danimarca 4
ES - Italia 4
AU - Australia 3
IR - Iran 3
PT - Portogallo 3
SC - Seychelles 3
CO - Colombia 2
CZ - Repubblica Ceca 2
IL - Israele 2
MD - Moldavia 2
NO - Norvegia 2
AE - Emirati Arabi Uniti 1
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
CR - Costa Rica 1
JO - Giordania 1
MO - Macao, regione amministrativa speciale della Cina 1
MU - Mauritius 1
MX - Messico 1
PA - Panama 1
RO - Romania 1
TR - Turchia 1
Totale 9.154
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Città #
Chandler 682
Beijing 519
Dublin 471
Santa Clara 362
Ann Arbor 280
Singapore 237
Jacksonville 223
Villeurbanne 158
Princeton 150
Medford 148
Warsaw 138
Vienna 133
Dearborn 132
Houston 130
Columbus 123
Nyköping 112
Fairfield 111
Dong Ket 107
Ashburn 105
Torino 80
Wilmington 79
Woodbridge 69
Boston 65
Boardman 60
Fremont 51
New York 46
Seattle 46
Guangzhou 42
Cambridge 41
Munich 41
Milan 31
Redwood City 31
Ottawa 30
Düsseldorf 25
Brussels 24
Hangzhou 24
Norwalk 20
Pisa 20
Washington 18
Des Moines 17
Nanjing 17
Verona 17
Falls Church 15
Hefei 14
Braunschweig 13
Jakarta 13
Kunming 13
Toronto 13
Mumbai 12
Los Angeles 11
Nanchang 11
Moscow 10
Fuzhou 9
Lachine 9
Mountain View 9
Rome 9
Shanghai 9
Hebei 8
Pune 8
Bagnacavallo 7
Helsinki 7
Tulsa 7
Zhengzhou 7
Bratislava 6
Buffalo 6
Hanover 6
Musashino 6
San Diego 6
Tokyo 6
Changsha 5
Philadelphia 5
Pittsburgh 5
Redmond 5
Amsterdam 4
Bonn 4
Changchun 4
Chengdu 4
Delhi 4
Gwangjin-gu 4
Indianapolis 4
Wuxi 4
Chiyoda-ku 3
Copenhagen 3
Heidelberg 3
Hong Kong 3
Iesi 3
Kumar 3
La Terrasse 3
Naaldwijk 3
Napoli 3
Palermo 3
San Jose 3
San Mateo 3
Shenzhen 3
Strasbourg 3
Taipei 3
Turin 3
Umeda 3
Venezia 3
Wuhan 3
Totale 5.574
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Nome #
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae 199
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 196
Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors. 182
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 154
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 144
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 141
Aminopropylindenes derived from Grundmann’s ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 138
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 126
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 118
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 106
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 106
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 105
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 99
4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase 97
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 95
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 93
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis. 91
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors 91
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 90
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 87
Azasqualeni N-ossidi e bis-azasqualeni, inibitori dell'enzima squalene epossido ciclasi. 87
POLICOSANOLI DA PULA DI RISO 86
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae. 84
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 84
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors. 83
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 83
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 82
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 82
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase. 82
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 82
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 81
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 81
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 80
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. 80
Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts 80
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 79
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 79
2,3-Oxidosqualene cyclase and squalene epoxidase as target enzymes for the development of new sterol biosynthesis inhibitors 79
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 79
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 78
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 78
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 78
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 77
3-carboxy-4-nitrophenyl-dithio-1,1'-2-trisnorsqualene: a site directed inactivator of yeast oxidosqualene cyclase 77
Characterization of C-4 demethylation complex of cholesterol biosynthesis 77
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. 76
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 76
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 76
Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from a downstream 3-ketoreductase activity (Erg27) in the yeast ergosterol biosynthetic pathway 75
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors 75
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 74
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 74
2,3-oxidosqualene cyclase from yeast: a target enzyme for drug discovery. 74
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 73
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 73
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 73
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 72
Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives. 72
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 72
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 71
The 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity in yeast 71
Thiol-modifying Inhibitors for Understanding Squalene Cyclase Function. Eur. J. Biochem. (2002) 269, 2108-2116. 70
Thiol-modifying agents as tools for understanding the function of squalene cyclase 70
Systematic analysis of yeast strains with possible defects in lipid metabolism 69
Novel Squalene-Hopene Cyclase Inhibitors derived from Hydroxycoumarins and Hydroxyacetophenones 68
Comparison of the mechanism of yeast oxidosqualene cyclase and bacterial squalene cyclase by using rationally designed inhibitors. 68
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 68
Interaction of Steroid-3-Keto Reductase and Oxidosqualene Cyclase, Two Key Enzymes in the Ergosterol Biosynthetic Pathway 68
Umbelliferone Aminoalkyl Derivatives, a New Class of Squalene-Hopene Cyclase Inhibitors 66
Evidence of the existence of an essential thiol group within the active site of oxidosqualene cyclase from Saccharomyces cerevisiae 66
Comparative properties of N-ethoxycarbonyl-D-phenylalanyl-L-prolyl-alpha-azalysine p-nitrophenyl ester and N-ethoxycarbonyl-D-phenylalanyl-alpha-azaprolyl-L-lysine p-nitrophenyl ester as subsrates of serine proteinases 66
Mutation analysis of the yeast 3-ketoreductase (Erg27p) and the effects on ergosterol biosynthesis 65
Total synthesis and inhibition of sterol biosynthesis by 10-azasqualene 2,3-epoxide, a high-energy intermediate analogue 65
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase. 65
The Interaction of 3-Keto Reductase and Oxidosqualene Cyclase, Two Key Enzymes in the Ergosterol Biosynthetic Pathway 65
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis, 64
Direzionamento di citotossine con anticorpi monoclonali per la terapia del cancro 64
Active site titration of bovine beta-trypsin by N alpha-(N,N-dimethylcarbamoyl)-alpha-aza-lysine p-nitrophenyl ester: kinetic and crystallographic analysis 64
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 64
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 64
Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae. 64
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 63
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 63
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 62
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 62
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 60
Sintesi ed attività biologica di azasqualeni, bis-azasqualeni e derivati. 60
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 60
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole. 59
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 58
Protein-protein interactions among ergosterol biosynthesis enzymes Erg7p/Erg27p and two-hybrid interactions involving Are1p and Are2p 58
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 58
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 58
Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase 57
Time-dependent inhibition of oxidosqualene cyclase by aza derivatives of squalene oxide. 56
Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study 56
Squalene- and nonsqualene-like thiol modifying agents as tools for understanding the function of squalene-hopene cyclase 55
Topology of DNA: when manipulation supports the lack of “space-filling” imagination 55
Inhibition of sterol biosynthesis by an aza analogue of 2,3-oxidosqualene. 54
Totale 8.113
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Categoria #
all - tutte 30.453
article - articoli 0
book - libri 0
conference - conferenze 13.024
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.477
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020782 0 0 0 0 0 181 162 59 114 111 107 48
2020/20211.050 142 48 51 59 118 55 53 35 146 65 102 176
2021/20221.147 17 28 55 59 62 48 61 64 51 69 284 349
2022/20231.849 225 142 27 200 194 500 170 107 150 10 97 27
2023/2024683 108 145 52 33 33 81 11 48 0 20 31 121
2024/2025963 13 79 43 194 580 54 0 0 0 0 0 0
Totale 9.536