CINECA IRIS Institutional Research Information System

BALLIANO, Gianni
 Distribuzione geografica
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Continente #
NA - Nord America 3.773
EU - Europa 2.863
AS - Asia 1.491
AF - Africa 82
Continente sconosciuto - Info sul continente non disponibili 12
SA - Sud America 10
OC - Oceania 3
Totale 8.234
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Nazione #
US - Stati Uniti d'America 3.719
CN - Cina 736
SE - Svezia 507
IE - Irlanda 472
DE - Germania 332
IT - Italia 304
FI - Finlandia 277
KR - Corea 274
FR - Francia 233
UA - Ucraina 230
SG - Singapore 155
PL - Polonia 139
GB - Regno Unito 138
AT - Austria 132
JP - Giappone 130
VN - Vietnam 128
SN - Senegal 79
CA - Canada 52
IN - India 37
RU - Federazione Russa 29
BE - Belgio 23
NL - Olanda 15
EU - Europa 12
HK - Hong Kong 8
BR - Brasile 6
SK - Slovacchia (Repubblica Slovacca) 6
UZ - Uzbekistan 6
CH - Svizzera 4
DK - Danimarca 4
ES - Italia 4
GR - Grecia 4
TW - Taiwan 4
AU - Australia 3
IR - Iran 3
PH - Filippine 3
PT - Portogallo 3
CO - Colombia 2
CZ - Repubblica Ceca 2
ID - Indonesia 2
IL - Israele 2
MD - Moldavia 2
NO - Norvegia 2
SC - Seychelles 2
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
CR - Costa Rica 1
MO - Macao, regione amministrativa speciale della Cina 1
MU - Mauritius 1
MX - Messico 1
RO - Romania 1
TR - Turchia 1
Totale 8.234
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Città #
Chandler 682
Beijing 519
Dublin 471
Ann Arbor 280
Jacksonville 223
Villeurbanne 158
Princeton 150
Medford 148
Warsaw 138
Dearborn 132
Vienna 132
Houston 130
Nyköping 112
Fairfield 111
Dong Ket 107
Ashburn 95
Singapore 85
Torino 80
Wilmington 79
Woodbridge 69
Boston 65
Boardman 60
Fremont 51
New York 46
Seattle 46
Cambridge 41
Munich 33
Milan 31
Redwood City 31
Guangzhou 28
Ottawa 28
Düsseldorf 25
Hangzhou 24
Brussels 23
Norwalk 20
Pisa 20
Washington 18
Des Moines 17
Nanjing 17
Verona 17
Falls Church 15
Hefei 14
Kunming 13
Braunschweig 11
Nanchang 11
Toronto 11
Los Angeles 10
Moscow 10
Fuzhou 9
Lachine 9
Mountain View 9
Rome 9
Shanghai 9
Hebei 8
Pune 8
Bagnacavallo 7
Tulsa 7
Zhengzhou 7
Bratislava 6
Buffalo 6
Hanover 6
Musashino 6
San Diego 6
Changsha 5
Philadelphia 5
Pittsburgh 5
Redmond 5
Amsterdam 4
Bonn 4
Changchun 4
Chengdu 4
Delhi 4
Indianapolis 4
Santa Clara 4
Wuxi 4
Chiyoda-ku 3
Copenhagen 3
Heidelberg 3
Helsinki 3
Iesi 3
Kumar 3
La Terrasse 3
Naaldwijk 3
Napoli 3
Palermo 3
San Mateo 3
Shenzhen 3
Strasbourg 3
Taipei 3
Tokyo 3
Umeda 3
Venezia 3
Wuhan 3
Yokohama 3
Aosta 2
Ardabil 2
Cadeo 2
Chaoyang 2
Chongqing 2
Clearwater 2
Totale 4.870
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Nome #
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae 191
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 189
Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors. 165
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 144
10 and 19-azasqualene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase from pig liver. 135
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 135
Aminopropylindenes derived from Grundmann’s ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 135
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 113
Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase. 111
Fenil vinil solfuri e metil vinil solfuri, inibitori specifici della ossidosqualene ciclasi di Trypanosoma cruzi e di S. cerevisiae. 97
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 94
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 93
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 92
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases 89
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 88
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis. 84
4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase 84
POLICOSANOLI DA PULA DI RISO 83
29-methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 81
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors 80
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 79
19-azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae 76
2,3-oxidosqualene cyclase and squalene epoxidase, as target enzymes for the development of new sterol biosynthesis inhibitors. 76
Azasqualeni N-ossidi e bis-azasqualeni, inibitori dell'enzima squalene epossido ciclasi. 76
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. 75
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae. 75
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase. 75
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 74
2,3-oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 74
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 74
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 74
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 73
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 73
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 72
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 72
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 71
2,3-Oxidosqualene cyclase and squalene epoxidase as target enzymes for the development of new sterol biosynthesis inhibitors 71
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 71
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 70
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 70
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 70
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 69
Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from a downstream 3-ketoreductase activity (Erg27) in the yeast ergosterol biosynthetic pathway 69
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 69
2,3-oxidosqualene cyclase from yeast: a target enzyme for drug discovery. 68
Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives. 68
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 68
Characterization of C-4 demethylation complex of cholesterol biosynthesis 68
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 68
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 67
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 67
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 66
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. 66
Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts 66
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 65
The 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity in yeast 65
Thiol-modifying agents as tools for understanding the function of squalene cyclase 65
Thiol-modifying Inhibitors for Understanding Squalene Cyclase Function. Eur. J. Biochem. (2002) 269, 2108-2116. 64
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 64
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors 64
Azasqualene alcohol and derivatives. New selective inhibitors of 2,3-oxidosqualene cyclase. 63
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 63
Systematic analysis of yeast strains with possible defects in lipid metabolism 62
Umbelliferone Aminoalkyl Derivatives, a New Class of Squalene-Hopene Cyclase Inhibitors 62
Mutation analysis of the yeast 3-ketoreductase (Erg27p) and the effects on ergosterol biosynthesis 62
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 62
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis, 61
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 61
3-carboxy-4-nitrophenyl-dithio-1,1'-2-trisnorsqualene: a site directed inactivator of yeast oxidosqualene cyclase 61
Interaction of Steroid-3-Keto Reductase and Oxidosqualene Cyclase, Two Key Enzymes in the Ergosterol Biosynthetic Pathway 60
The Interaction of 3-Keto Reductase and Oxidosqualene Cyclase, Two Key Enzymes in the Ergosterol Biosynthetic Pathway 60
Total synthesis and inhibition of sterol biosynthesis by 10-azasqualene 2,3-epoxide, a high-energy intermediate analogue 59
Comparison of the mechanism of yeast oxidosqualene cyclase and bacterial squalene cyclase by using rationally designed inhibitors. 59
Comparative properties of N-ethoxycarbonyl-D-phenylalanyl-L-prolyl-alpha-azalysine p-nitrophenyl ester and N-ethoxycarbonyl-D-phenylalanyl-alpha-azaprolyl-L-lysine p-nitrophenyl ester as subsrates of serine proteinases 59
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 58
Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae. 58
Direzionamento di citotossine con anticorpi monoclonali per la terapia del cancro 57
Sintesi ed attività biologica di azasqualeni, bis-azasqualeni e derivati. 57
Active site titration of bovine beta-trypsin by N alpha-(N,N-dimethylcarbamoyl)-alpha-aza-lysine p-nitrophenyl ester: kinetic and crystallographic analysis 57
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase. 56
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 56
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 55
Evidence of the existence of an essential thiol group within the active site of oxidosqualene cyclase from Saccharomyces cerevisiae 55
Novel Squalene-Hopene Cyclase Inhibitors derived from Hydroxycoumarins and Hydroxyacetophenones 54
Protein-protein interactions among ergosterol biosynthesis enzymes Erg7p/Erg27p and two-hybrid interactions involving Are1p and Are2p 54
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 54
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 54
Stereospecific inhibition of sterol biosynthesis in HEP G2 and Saccharomyces cerevisiae cell cultures by 29-methylidene-oxidosqualene derivatives. 53
Sterospecific irreversible inhibitors of liver and yeast oxidosqualene cyclase 53
Effect of proteases on microsomal oxidosqualene cyclases from Saccharomyces cerevisiae and Candida albicans 52
Stereospecific synthesis of trans-vinyl dioxidosqualene and b-hydrosulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors 51
Time-dependent inhibition of oxidosqualene cyclase by aza derivatives of squalene oxide. 51
Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study 51
Inhibition of sterol biosynthesis by an aza analogue of 2,3-oxidosqualene. 50
Topology of DNA: when manipulation supports the lack of “space-filling” imagination 49
Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase 49
Preparazione e attività antitumorale di un nuovo coniugato anticorpo-ricina ad alta specificità 48
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 48
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 48
Conversion of Squalene to the Pentacyclic Hopene. 47
Totale 7.319
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Categoria #
all - tutte 26.911
article - articoli 0
book - libri 0
conference - conferenze 11.436
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.347
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.090 0 66 93 78 71 181 162 59 114 111 107 48
2020/20211.050 142 48 51 59 118 55 53 35 146 65 102 176
2021/20221.147 17 28 55 59 62 48 61 64 51 69 284 349
2022/20231.849 225 142 27 200 194 500 170 107 150 10 97 27
2023/2024683 108 145 52 33 33 81 11 48 0 20 31 121
2024/202543 13 30 0 0 0 0 0 0 0 0 0 0
Totale 8.616