CINECA IRIS Institutional Research Information System

GOITRE, Luca
 Distribuzione geografica
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Continente #
NA - Nord America 3.295
EU - Europa 1.747
AS - Asia 990
AF - Africa 43
SA - Sud America 18
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 3
Totale 6.103
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Nazione #
US - Stati Uniti d'America 3.257
IT - Italia 511
CN - Cina 457
SG - Singapore 245
IE - Irlanda 212
SE - Svezia 163
UA - Ucraina 146
DE - Germania 145
FR - Francia 142
FI - Finlandia 134
KR - Corea 82
AT - Austria 63
GB - Regno Unito 58
PL - Polonia 58
JP - Giappone 48
VN - Vietnam 48
CA - Canada 33
SN - Senegal 32
BE - Belgio 24
ID - Indonesia 23
IN - India 19
NL - Olanda 19
HK - Hong Kong 18
DK - Danimarca 11
BR - Brasile 10
RO - Romania 9
TR - Turchia 9
CZ - Repubblica Ceca 8
ES - Italia 8
PK - Pakistan 7
AU - Australia 6
GR - Grecia 6
IL - Israele 6
TW - Taiwan 6
CH - Svizzera 5
LK - Sri Lanka 5
MX - Messico 5
RU - Federazione Russa 4
AZ - Azerbaigian 3
BG - Bulgaria 3
CO - Colombia 3
EE - Estonia 3
EG - Egitto 3
EU - Europa 3
NO - Norvegia 3
TH - Thailandia 3
ZA - Sudafrica 3
AL - Albania 2
BY - Bielorussia 2
DZ - Algeria 2
EC - Ecuador 2
HU - Ungheria 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
AR - Argentina 1
BD - Bangladesh 1
CI - Costa d'Avorio 1
CY - Cipro 1
GE - Georgia 1
IR - Iran 1
KG - Kirghizistan 1
LT - Lituania 1
LU - Lussemburgo 1
LY - Libia 1
MD - Moldavia 1
MK - Macedonia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PE - Perù 1
PH - Filippine 1
PS - Palestinian Territory 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
UY - Uruguay 1
Totale 6.103
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Città #
Chandler 511
Torino 248
Beijing 215
Singapore 211
Dublin 210
Santa Clara 205
Fairfield 204
Ashburn 183
Houston 149
Jacksonville 121
Ann Arbor 112
Wilmington 105
Woodbridge 92
Villeurbanne 90
Seattle 84
Cambridge 76
Pisa 72
Medford 68
Fremont 66
Princeton 65
Dearborn 64
Vienna 61
Columbus 56
Nyköping 56
Warsaw 53
Guangzhou 29
Boston 27
Dong Ket 27
New York 27
Nanjing 23
Brussels 22
Shanghai 22
Toronto 21
Xian 21
Milan 20
Redwood City 20
Jakarta 19
Los Angeles 18
Düsseldorf 15
Hefei 14
Norwalk 14
Rome 14
San Diego 14
Boardman 11
Helsinki 11
Hangzhou 10
Phoenix 10
Siena 10
Washington 10
Munich 9
San Mateo 9
Tokyo 9
Falls Church 8
Frankfurt am Main 8
Kunming 8
Wuhan 8
Edinburgh 7
Rochester 7
Changsha 6
Copenhagen 6
Grafing 6
Hong Kong 6
Jinan 6
Pune 6
Taipei 6
Tel Aviv 6
Amsterdam 5
Brno 5
Istanbul 5
London 5
Nanchang 5
Suizenji 5
Turin 5
Aosta 4
Colombo 4
Madrid 4
Mountain View 4
Osaka 4
Palermo 4
Paris 4
Rende 4
Seoul 4
Silver Spring 4
Albany 3
Arezzo 3
Baku 3
Cairo 3
Central District 3
Chicago 3
Guidonia 3
Gujranwala 3
Gävle 3
Hamburg 3
Hayling 3
Hellerup 3
Invorio Inferiore 3
Lachine 3
Leicester 3
Napoli 3
Nashville 3
Totale 4.053
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Nome #
Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast 339
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 252
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium 209
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease 202
Defective autophagy is a key feature of cerebral cavernous malformations 186
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 185
KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun 178
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies 170
Molecular Crosstalk between Integrins and Cadherins: Do Reactive Oxygen Species Set the Talk? 151
Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1 146
KRIT1 and Reactive Oxigen Species: a novel molecular pathway involved in Cerebral Cavernous Malformations. 140
Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases 140
CCM Italia: pazienti, clinici e ricercatori “in rete” per migliorare conoscenza, management clinico e ricerca sulle Malformazioni Cavernose Cerebrali 138
Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast 136
KRIT1 regulates the homeostasis of intracellular reactive oxygen species 132
Cerebral Cavernous Malformations: the CCM Italia research network offers new therapeutic perspectives 119
The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications 114
Combined Pulldown and Time-Lapse Microscopy Studies for Determining the Role of Rap1 in the Crosstalk Between Integrins and Cadherins 111
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis 106
Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties 98
Fluorescence Microscopy Study of Rap1 Subcellular Localization 97
The Ras Superfamily of Small GTPases: The Unlocked Secrets 96
Rap1: una proteina chiave nel crosstalk tra caderine ed integrine 95
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 94
Characterization of the cellular functions of KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1) 92
Novel insights into the relationship between KRIT1 and ROS homeostasis: KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress response. 91
KRIT1, a protein involved in Cerebral Cavernous Malformation pathogenesis, is a target of oxidative stress 90
KRIT1 regulates cell adhesion by controlling ICAP1A functions and cytoskeleton dynamics 90
Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches 90
KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1), acts as a modulator of RAP1A and ICAP1A functions 87
Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties 87
Oxidative stress and Cerebral Cavernous Malformations (CCM): from disease mechanisms toward prevention and treatment 87
Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis 85
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations 85
Novel insights into the role of oxidative stress in CCM pathogenesis 82
Mutation Analysis of CCM1, CCM2 and CCM3 Genes in a Cohort of Italian Patients with Cerebral Cavernous Malformation 78
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 77
Metabolic engineering of Saccharomyces cerevisiae for the production of plant derived antioxidants 76
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 74
Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications 73
KRIT1A, a protein involved in the human disease Cerebral Cavernous Malformation, is a molecular sensor for oxidative stress 72
Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease 72
Krit1 knockout down-regulates Rap1A activity: a possible explanation for Cerebral Cavenous Malformations pathogenesis 69
KRIT1 helps cells to prevent oxidative stress. 69
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis. 68
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 67
Genetic and cellular basis of Cerebral Cavernous Malformations: implications for clinical management 65
KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress responses 64
Krit1 knockout mice as animal models for Cerebral Cavernous Malformations pathogenesis 62
Novel signaling pathways regulating KRIT1 nucleocytoplasmic shuttling and its role in CCM pathogenesis. 62
Novel insights into the implication of KRIT1 in the maintenance of ROS homeostasis 60
Role of KRIT1 in the pathogenesis of Cerebral Cavernous Malformations (CCM): from disease mechanisms toward pharmacological therapies 59
High yield production of avenanthramide analogous endowed with antioxidant properties 58
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics. 57
Structural and functional differences of Krit1A and Krit1B isoforms: a framework for understanding CCM pathogenesis. IX Convegno FISV (Federazione Italiana Scienze della Vita). Riva del Garda (TN), 26-29 Settembre 2007 55
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation 55
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 50
Setting up of a yeast based system for the production of plant derived antioxidants 49
KRIT1 helps cells to prevent oxidative stress. 45
null 43
KRIT1, a disease gene responsible for cerebral cavernous malformations (CCM), is involved in cell defences against oxidative stress. 39
Ras GTPases Are Both Regulators and Effectors of Redox Agents 39
Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress 37
Totale 6.294
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Categoria #
all - tutte 18.501
article - articoli 0
book - libri 0
conference - conferenze 10.246
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.747
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020568 0 0 0 0 0 117 100 65 91 91 55 49
2020/2021710 68 57 84 76 70 29 47 33 76 54 54 62
2021/2022750 27 20 22 38 33 24 48 57 9 62 219 191
2022/20231.173 145 125 52 162 79 260 78 79 104 17 54 18
2023/2024491 49 94 28 25 43 79 21 27 8 24 24 69
2024/2025717 20 75 60 139 329 94 0 0 0 0 0 0
Totale 6.294