GOITRE, Luca
 Distribuzione geografica
Continente #
NA - Nord America 2.896
EU - Europa 1.686
AS - Asia 651
AF - Africa 42
SA - Sud America 15
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 3
Totale 5.300
Nazione #
US - Stati Uniti d'America 2.862
IT - Italia 500
CN - Cina 387
IE - Irlanda 212
SE - Svezia 162
UA - Ucraina 146
FR - Francia 135
DE - Germania 133
FI - Finlandia 127
KR - Corea 81
AT - Austria 62
PL - Polonia 58
GB - Regno Unito 56
JP - Giappone 47
VN - Vietnam 47
SN - Senegal 32
CA - Canada 30
BE - Belgio 23
IN - India 17
HK - Hong Kong 16
SG - Singapore 16
NL - Olanda 15
BR - Brasile 10
RO - Romania 9
ES - Italia 8
TR - Turchia 8
DK - Danimarca 7
AU - Australia 6
GR - Grecia 6
TW - Taiwan 6
CH - Svizzera 5
IL - Israele 5
LK - Sri Lanka 5
ID - Indonesia 4
MX - Messico 4
EE - Estonia 3
EG - Egitto 3
EU - Europa 3
NO - Norvegia 3
RU - Federazione Russa 3
TH - Thailandia 3
ZA - Sudafrica 3
AL - Albania 2
BG - Bulgaria 2
BY - Bielorussia 2
CO - Colombia 2
DZ - Algeria 2
HU - Ungheria 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
AR - Argentina 1
BD - Bangladesh 1
CZ - Repubblica Ceca 1
EC - Ecuador 1
IR - Iran 1
LU - Lussemburgo 1
LY - Libia 1
MD - Moldavia 1
MK - Macedonia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PE - Perù 1
PH - Filippine 1
PK - Pakistan 1
PS - Palestinian Territory 1
RS - Serbia 1
TN - Tunisia 1
Totale 5.300
Città #
Chandler 511
Torino 248
Beijing 211
Dublin 210
Fairfield 204
Ashburn 176
Houston 148
Jacksonville 121
Ann Arbor 112
Wilmington 105
Woodbridge 92
Villeurbanne 90
Seattle 84
Cambridge 76
Pisa 72
Medford 68
Fremont 66
Princeton 65
Dearborn 64
Vienna 60
Nyköping 56
Warsaw 53
Boston 27
Dong Ket 27
New York 27
Brussels 21
Nanjing 21
Xian 21
Milan 20
Redwood City 20
Toronto 18
Shanghai 17
Düsseldorf 15
Norwalk 14
San Diego 14
Hefei 13
Rome 12
Singapore 12
Guangzhou 11
Hangzhou 10
Phoenix 10
Siena 10
Washington 10
Boardman 9
San Mateo 9
Falls Church 8
Tokyo 8
Rochester 7
Wuhan 7
Changsha 6
Edinburgh 6
Grafing 6
Jinan 6
Kunming 6
Taipei 6
Amsterdam 5
Copenhagen 5
Istanbul 5
London 5
Los Angeles 5
Nanchang 5
Suizenji 5
Tel Aviv 5
Aosta 4
Colombo 4
Helsinki 4
Hong Kong 4
Madrid 4
Mountain View 4
Munich 4
Osaka 4
Palermo 4
Pune 4
Rende 4
Seoul 4
Silver Spring 4
Turin 4
Albany 3
Arezzo 3
Cairo 3
Central District 3
Chicago 3
Guidonia 3
Hamburg 3
Hayling 3
Invorio Inferiore 3
Lachine 3
Leicester 3
Napoli 3
Ottawa 3
Rho 3
Tianjin 3
Vermezzo 3
Verona 3
Belém 2
Buffalo 2
Chengdu 2
Chico 2
Chieti 2
Denton 2
Totale 3.485
Nome #
Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast 322
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 213
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium 201
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease 192
Defective autophagy is a key feature of cerebral cavernous malformations 176
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 169
KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun 159
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies 156
Molecular Crosstalk between Integrins and Cadherins: Do Reactive Oxygen Species Set the Talk? 145
Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1 135
Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast 130
CCM Italia: pazienti, clinici e ricercatori “in rete” per migliorare conoscenza, management clinico e ricerca sulle Malformazioni Cavernose Cerebrali 125
Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases 124
KRIT1 regulates the homeostasis of intracellular reactive oxygen species 116
KRIT1 and Reactive Oxigen Species: a novel molecular pathway involved in Cerebral Cavernous Malformations. 114
The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications 108
Cerebral Cavernous Malformations: the CCM Italia research network offers new therapeutic perspectives 106
Combined Pulldown and Time-Lapse Microscopy Studies for Determining the Role of Rap1 in the Crosstalk Between Integrins and Cadherins 98
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis 90
Fluorescence Microscopy Study of Rap1 Subcellular Localization 90
Rap1: una proteina chiave nel crosstalk tra caderine ed integrine 87
Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties 86
The Ras Superfamily of Small GTPases: The Unlocked Secrets 83
Characterization of the cellular functions of KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1) 80
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 79
KRIT1 regulates cell adhesion by controlling ICAP1A functions and cytoskeleton dynamics 78
KRIT1, a protein involved in Cerebral Cavernous Malformation pathogenesis, is a target of oxidative stress 77
Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties 77
Novel insights into the relationship between KRIT1 and ROS homeostasis: KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress response. 76
Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches 76
Oxidative stress and Cerebral Cavernous Malformations (CCM): from disease mechanisms toward prevention and treatment 74
KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1), acts as a modulator of RAP1A and ICAP1A functions 71
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations 69
Mutation Analysis of CCM1, CCM2 and CCM3 Genes in a Cohort of Italian Patients with Cerebral Cavernous Malformation 68
Novel insights into the role of oxidative stress in CCM pathogenesis 67
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 66
Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis 66
Metabolic engineering of Saccharomyces cerevisiae for the production of plant derived antioxidants 65
Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications 63
KRIT1A, a protein involved in the human disease Cerebral Cavernous Malformation, is a molecular sensor for oxidative stress 61
Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease 60
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 60
Genetic and cellular basis of Cerebral Cavernous Malformations: implications for clinical management 57
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis. 56
KRIT1 helps cells to prevent oxidative stress. 55
Krit1 knockout down-regulates Rap1A activity: a possible explanation for Cerebral Cavenous Malformations pathogenesis 54
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 53
Novel insights into the implication of KRIT1 in the maintenance of ROS homeostasis 53
Krit1 knockout mice as animal models for Cerebral Cavernous Malformations pathogenesis 51
KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress responses 50
Structural and functional differences of Krit1A and Krit1B isoforms: a framework for understanding CCM pathogenesis. IX Convegno FISV (Federazione Italiana Scienze della Vita). Riva del Garda (TN), 26-29 Settembre 2007 47
Role of KRIT1 in the pathogenesis of Cerebral Cavernous Malformations (CCM): from disease mechanisms toward pharmacological therapies 47
High yield production of avenanthramide analogous endowed with antioxidant properties 46
Novel signaling pathways regulating KRIT1 nucleocytoplasmic shuttling and its role in CCM pathogenesis. 45
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics. 44
null 43
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation 43
Setting up of a yeast based system for the production of plant derived antioxidants 38
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 36
KRIT1 helps cells to prevent oxidative stress. 35
Ras GTPases Are Both Regulators and Effectors of Redox Agents 32
KRIT1, a disease gene responsible for cerebral cavernous malformations (CCM), is involved in cell defences against oxidative stress. 31
Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress 17
Totale 5.491
Categoria #
all - tutte 14.731
article - articoli 0
book - libri 0
conference - conferenze 8.024
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.755


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019240 0 0 0 0 0 0 0 0 0 0 158 82
2019/2020868 48 40 45 113 54 117 100 65 91 91 55 49
2020/2021710 68 57 84 76 70 29 47 33 76 54 54 62
2021/2022750 27 20 22 38 33 24 48 57 9 62 219 191
2022/20231.173 145 125 52 162 79 260 78 79 104 17 54 18
2023/2024405 49 94 28 25 43 79 21 27 8 24 7 0
Totale 5.491