GOITRE, Luca
 Distribuzione geografica
Continente #
NA - Nord America 5.051
AS - Asia 2.472
EU - Europa 2.318
SA - Sud America 277
Continente sconosciuto - Info sul continente non disponibili 212
AF - Africa 89
OC - Oceania 14
Totale 10.433
Nazione #
US - Stati Uniti d'America 4.908
SG - Singapore 963
IT - Italia 761
CN - Cina 664
VN - Vietnam 288
FR - Francia 226
IE - Irlanda 217
DE - Germania 208
BR - Brasile 201
SE - Svezia 179
FI - Finlandia 163
UA - Ucraina 148
GB - Regno Unito 98
KR - Corea 88
CA - Canada 86
HK - Hong Kong 82
IN - India 80
JP - Giappone 79
PL - Polonia 74
AT - Austria 71
ID - Indonesia 41
NL - Olanda 40
SN - Senegal 32
AR - Argentina 24
BE - Belgio 24
MX - Messico 21
EC - Ecuador 19
IQ - Iraq 19
TR - Turchia 19
BD - Bangladesh 18
JM - Giamaica 18
PK - Pakistan 15
ES - Italia 14
PH - Filippine 14
AU - Australia 13
CH - Svizzera 13
ZA - Sudafrica 13
RO - Romania 12
TH - Thailandia 12
CO - Colombia 11
DK - Danimarca 11
NP - Nepal 11
SA - Arabia Saudita 11
TW - Taiwan 11
CL - Cile 10
IL - Israele 10
CZ - Repubblica Ceca 9
DZ - Algeria 8
RU - Federazione Russa 8
EG - Egitto 7
GR - Grecia 7
LT - Lituania 7
MA - Marocco 7
MY - Malesia 6
TN - Tunisia 6
AE - Emirati Arabi Uniti 5
AZ - Azerbaigian 5
LK - Sri Lanka 5
UY - Uruguay 5
BG - Bulgaria 4
CR - Costa Rica 4
HN - Honduras 4
TT - Trinidad e Tobago 4
AL - Albania 3
BY - Bielorussia 3
CY - Cipro 3
EE - Estonia 3
ET - Etiopia 3
EU - Europa 3
JO - Giordania 3
KG - Kirghizistan 3
KZ - Kazakistan 3
NO - Norvegia 3
PR - Porto Rico 3
VE - Venezuela 3
CI - Costa d'Avorio 2
HU - Ungheria 2
KE - Kenya 2
MN - Mongolia 2
MU - Mauritius 2
OM - Oman 2
PE - Perù 2
PY - Paraguay 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
BW - Botswana 1
CV - Capo Verde 1
GA - Gabon 1
GE - Georgia 1
IR - Iran 1
KW - Kuwait 1
LB - Libano 1
LU - Lussemburgo 1
LY - Libia 1
MD - Moldavia 1
MK - Macedonia 1
Totale 10.212
Città #
Singapore 550
Chandler 512
San Jose 384
Ashburn 368
Beijing 311
Santa Clara 253
Torino 248
Dublin 214
Fairfield 205
Houston 156
Jacksonville 125
Ann Arbor 113
Wilmington 105
Los Angeles 100
Woodbridge 92
Seattle 90
Villeurbanne 90
Ho Chi Minh City 77
Cambridge 76
Council Bluffs 75
Milan 73
Pisa 72
Medford 68
Fremont 67
Princeton 65
Columbus 64
Dearborn 64
New York 63
Vienna 63
Warsaw 61
Hanoi 60
The Dalles 60
Nyköping 56
Lauterbourg 55
Hong Kong 53
Rome 52
Munich 35
Dallas 34
Tokyo 34
Toronto 33
Boston 32
Buffalo 32
Guangzhou 31
Jakarta 31
Helsinki 30
Dong Ket 27
Nanjing 27
Phoenix 27
Frankfurt am Main 25
Shanghai 23
Brussels 22
Springfield 21
Xian 21
Naples 20
Redwood City 20
São Paulo 20
Düsseldorf 19
Orem 19
Da Nang 18
Hefei 17
Amsterdam 15
Denver 14
Norwalk 14
San Diego 14
Washington 14
London 13
Turin 13
Boardman 12
Montreal 12
Chicago 11
Hangzhou 11
Chennai 10
Kingston 10
Kunming 10
Nuremberg 10
Siena 10
Turku 10
Brooklyn 9
Coimbatore 9
Curitiba 9
Manchester 9
Paris 9
San Francisco 9
San Mateo 9
Seoul 9
Wuhan 9
Changsha 8
Edinburgh 8
Falls Church 8
Istanbul 8
Redondo Beach 8
Rio de Janeiro 8
Stockholm 8
Verona 8
Atlanta 7
Belo Horizonte 7
Biên Hòa 7
Guayaquil 7
Hải Dương 7
Johannesburg 7
Totale 6.148
Nome #
Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast 406
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 372
Characterization of the cellular functions of KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1) 341
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease 274
Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases 258
Defective autophagy is a key feature of cerebral cavernous malformations 255
KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun 254
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 251
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies 250
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium 244
CCM Italia: pazienti, clinici e ricercatori “in rete” per migliorare conoscenza, management clinico e ricerca sulle Malformazioni Cavernose Cerebrali 234
Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1 225
KRIT1 and Reactive Oxigen Species: a novel molecular pathway involved in Cerebral Cavernous Malformations. 220
KRIT1 regulates the homeostasis of intracellular reactive oxygen species 211
Molecular Crosstalk between Integrins and Cadherins: Do Reactive Oxygen Species Set the Talk? 205
Cerebral Cavernous Malformations: the CCM Italia research network offers new therapeutic perspectives 197
Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast 192
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 190
Combined Pulldown and Time-Lapse Microscopy Studies for Determining the Role of Rap1 in the Crosstalk Between Integrins and Cadherins 187
Novel insights into the relationship between KRIT1 and ROS homeostasis: KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress response. 178
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 167
Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress 165
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 163
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis 162
The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications 162
Novel insights into the role of oxidative stress in CCM pathogenesis 161
Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties 159
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations 159
Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis 154
KRIT1, a protein involved in Cerebral Cavernous Malformation pathogenesis, is a target of oxidative stress 153
Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications 153
KRIT1 regulates cell adhesion by controlling ICAP1A functions and cytoskeleton dynamics 151
Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches 148
KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1), acts as a modulator of RAP1A and ICAP1A functions 147
Fluorescence Microscopy Study of Rap1 Subcellular Localization 145
Mutation Analysis of CCM1, CCM2 and CCM3 Genes in a Cohort of Italian Patients with Cerebral Cavernous Malformation 143
The Ras Superfamily of Small GTPases: The Unlocked Secrets 141
Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties 140
Oxidative stress and Cerebral Cavernous Malformations (CCM): from disease mechanisms toward prevention and treatment 137
Genetic and cellular basis of Cerebral Cavernous Malformations: implications for clinical management 133
Rap1: una proteina chiave nel crosstalk tra caderine ed integrine 128
KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress responses 128
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 127
Krit1 knockout down-regulates Rap1A activity: a possible explanation for Cerebral Cavenous Malformations pathogenesis 124
Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease 123
KRIT1 helps cells to prevent oxidative stress. 122
Krit1 knockout mice as animal models for Cerebral Cavernous Malformations pathogenesis 121
Metabolic engineering of Saccharomyces cerevisiae for the production of plant derived antioxidants 118
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis. 117
Role of KRIT1 in the pathogenesis of Cerebral Cavernous Malformations (CCM): from disease mechanisms toward pharmacological therapies 117
Novel signaling pathways regulating KRIT1 nucleocytoplasmic shuttling and its role in CCM pathogenesis. 113
High yield production of avenanthramide analogous endowed with antioxidant properties 113
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics. 112
KRIT1A, a protein involved in the human disease Cerebral Cavernous Malformation, is a molecular sensor for oxidative stress 111
Structural and functional differences of Krit1A and Krit1B isoforms: a framework for understanding CCM pathogenesis. IX Convegno FISV (Federazione Italiana Scienze della Vita). Riva del Garda (TN), 26-29 Settembre 2007 99
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation 99
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 98
Novel insights into the implication of KRIT1 in the maintenance of ROS homeostasis 98
KRIT1 helps cells to prevent oxidative stress. 94
KRIT1, a disease gene responsible for cerebral cavernous malformations (CCM), is involved in cell defences against oxidative stress. 92
Setting up of a yeast based system for the production of plant derived antioxidants 82
Ras GTPases Are Both Regulators and Effectors of Redox Agents 67
null 43
Totale 10.433
Categoria #
all - tutte 30.658
article - articoli 0
book - libri 0
conference - conferenze 17.531
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.189


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022703 0 0 22 38 33 24 48 57 9 62 219 191
2022/20231.173 145 125 52 162 79 260 78 79 104 17 54 18
2023/2024491 49 94 28 25 43 79 21 27 8 24 24 69
2024/20251.367 20 75 60 139 329 106 20 42 209 73 126 168
2025/20262.940 264 97 148 337 378 147 491 80 258 245 117 378
2026/2027549 126 357 66 0 0 0 0 0 0 0 0 0
Totale 10.433