GOITRE, Luca
 Distribuzione geografica
Continente #
NA - Nord America 3.707
EU - Europa 1.935
AS - Asia 1.882
SA - Sud America 202
AF - Africa 67
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 3
Totale 7.804
Nazione #
US - Stati Uniti d'America 3.645
SG - Singapore 755
CN - Cina 589
IT - Italia 548
IE - Irlanda 214
DE - Germania 191
SE - Svezia 169
BR - Brasile 159
FR - Francia 159
UA - Ucraina 147
FI - Finlandia 145
VN - Vietnam 137
KR - Corea 86
GB - Regno Unito 84
AT - Austria 70
PL - Polonia 69
IN - India 62
JP - Giappone 62
HK - Hong Kong 48
CA - Canada 44
ID - Indonesia 38
SN - Senegal 32
NL - Olanda 30
BE - Belgio 24
TR - Turchia 17
AR - Argentina 16
MX - Messico 15
EC - Ecuador 13
ZA - Sudafrica 13
ES - Italia 12
DK - Danimarca 11
PK - Pakistan 9
RO - Romania 9
TW - Taiwan 9
CZ - Repubblica Ceca 8
IL - Israele 8
IQ - Iraq 8
AU - Australia 7
CH - Svizzera 7
TH - Thailandia 7
CO - Colombia 6
GR - Grecia 6
AE - Emirati Arabi Uniti 5
BD - Bangladesh 5
EG - Egitto 5
LK - Sri Lanka 5
MY - Malesia 5
RU - Federazione Russa 5
SA - Arabia Saudita 5
AZ - Azerbaigian 4
DZ - Algeria 4
LT - Lituania 4
PH - Filippine 4
BG - Bulgaria 3
BY - Bielorussia 3
CL - Cile 3
EE - Estonia 3
EU - Europa 3
KG - Kirghizistan 3
MA - Marocco 3
NO - Norvegia 3
TN - Tunisia 3
AL - Albania 2
CI - Costa d'Avorio 2
HN - Honduras 2
HU - Ungheria 2
NP - Nepal 2
RS - Serbia 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
CV - Capo Verde 1
CY - Cipro 1
ET - Etiopia 1
GE - Georgia 1
IR - Iran 1
KE - Kenya 1
KW - Kuwait 1
KZ - Kazakistan 1
LU - Lussemburgo 1
LY - Libia 1
MD - Moldavia 1
MK - Macedonia 1
NZ - Nuova Zelanda 1
PE - Perù 1
PS - Palestinian Territory 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
SL - Sierra Leone 1
TT - Trinidad e Tobago 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 7.804
Città #
Chandler 511
Singapore 387
Beijing 295
Ashburn 262
Torino 248
Dublin 211
Santa Clara 211
Fairfield 204
Houston 151
Jacksonville 122
Ann Arbor 113
Wilmington 105
Woodbridge 92
Villeurbanne 90
Seattle 86
Los Angeles 79
Cambridge 76
Pisa 72
Medford 68
Fremont 66
Princeton 65
Dearborn 64
Columbus 63
Vienna 62
Warsaw 59
Nyköping 56
New York 46
Munich 35
Ho Chi Minh City 32
Boston 30
Guangzhou 30
Jakarta 30
Buffalo 28
Dong Ket 27
Nanjing 26
Hong Kong 25
Milan 25
Dallas 23
Brussels 22
Shanghai 22
Toronto 22
Phoenix 21
Xian 21
Redwood City 20
Düsseldorf 19
Rome 18
Tokyo 18
Hefei 17
Frankfurt am Main 16
Hanoi 15
Norwalk 14
San Diego 14
Denver 13
São Paulo 13
Boardman 12
Helsinki 12
London 11
Washington 11
Hangzhou 10
Siena 10
Turku 10
Coimbatore 9
Kunming 9
San Mateo 9
Wuhan 9
Amsterdam 8
Edinburgh 8
Falls Church 8
Naples 8
Redondo Beach 8
Seoul 8
Turin 8
Belo Horizonte 7
Changsha 7
Da Nang 7
Istanbul 7
Johannesburg 7
Kolkata 7
Nuremberg 7
Rio de Janeiro 7
Rochester 7
Stockholm 7
The Dalles 7
Biên Hòa 6
Brooklyn 6
Chicago 6
Copenhagen 6
Curitiba 6
Grafing 6
Guayaquil 6
Hyderabad 6
Jinan 6
Madrid 6
Palermo 6
Paris 6
Poplar 6
Pune 6
San Francisco 6
Taipei 6
Tel Aviv 6
Totale 4.807
Nome #
Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast 376
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 310
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease 232
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium 226
KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun 214
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 213
Defective autophagy is a key feature of cerebral cavernous malformations 212
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies 208
Biological activities, health benefits, and therapeutic properties of avenanthramides: From skin protection to prevention and treatment of cerebrovascular diseases 196
Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1 178
Molecular Crosstalk between Integrins and Cadherins: Do Reactive Oxygen Species Set the Talk? 173
CCM Italia: pazienti, clinici e ricercatori “in rete” per migliorare conoscenza, management clinico e ricerca sulle Malformazioni Cavernose Cerebrali 169
KRIT1 and Reactive Oxigen Species: a novel molecular pathway involved in Cerebral Cavernous Malformations. 164
KRIT1 regulates the homeostasis of intracellular reactive oxygen species 164
Cerebral Cavernous Malformations: the CCM Italia research network offers new therapeutic perspectives 162
Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast 152
Combined Pulldown and Time-Lapse Microscopy Studies for Determining the Role of Rap1 in the Crosstalk Between Integrins and Cadherins 141
Characterization of the cellular functions of KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1) 135
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis 135
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 135
The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications 131
Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties 131
KRIT1 regulates cell adhesion by controlling ICAP1A functions and cytoskeleton dynamics 123
Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis 120
Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches 119
Novel insights into the role of oxidative stress in CCM pathogenesis 118
Novel insights into the relationship between KRIT1 and ROS homeostasis: KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress response. 116
Fluorescence Microscopy Study of Rap1 Subcellular Localization 115
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations 115
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics and cell resistance to oxidative stress 113
The Ras Superfamily of Small GTPases: The Unlocked Secrets 113
Oxidative stress and Cerebral Cavernous Malformations (CCM): from disease mechanisms toward prevention and treatment 112
Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications 111
KRIT1, a protein involved in Cerebral Cavernous Malformation pathogenesis, is a target of oxidative stress 110
Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties 110
KRIT1, the disease gene responsible for type 1 Cerebral Cavernous Malformations (CCM1), acts as a modulator of RAP1A and ICAP1A functions 108
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 108
Rap1: una proteina chiave nel crosstalk tra caderine ed integrine 107
Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress 102
KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress responses 99
Mutation Analysis of CCM1, CCM2 and CCM3 Genes in a Cohort of Italian Patients with Cerebral Cavernous Malformation 98
Metabolic engineering of Saccharomyces cerevisiae for the production of plant derived antioxidants 95
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 93
Production of KRIT1-knockout and KRIT1-knockin Mouse Embryonic Fibroblasts as Cellular Models of CCM Disease 93
Identification of a novel KRIT1 interactor involved in the control of actin cytoskeleton dynamics. 91
KRIT1 helps cells to prevent oxidative stress. 90
Genetic and cellular basis of Cerebral Cavernous Malformations: implications for clinical management 90
Krit1 knockout down-regulates Rap1A activity: a possible explanation for Cerebral Cavenous Malformations pathogenesis 89
KRIT1A, a protein involved in the human disease Cerebral Cavernous Malformation, is a molecular sensor for oxidative stress 89
Structural and Functional Differences between KRIT1A and KRIT1B Isoforms: a Framework for Understanding CCM Pathogenesis. 88
Role of KRIT1 in the pathogenesis of Cerebral Cavernous Malformations (CCM): from disease mechanisms toward pharmacological therapies 88
Krit1 knockout mice as animal models for Cerebral Cavernous Malformations pathogenesis 85
High yield production of avenanthramide analogous endowed with antioxidant properties 83
Novel signaling pathways regulating KRIT1 nucleocytoplasmic shuttling and its role in CCM pathogenesis. 81
Novel insights into the implication of KRIT1 in the maintenance of ROS homeostasis 75
KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species. 69
KRIT1 helps cells to prevent oxidative stress. 69
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation 69
Structural and functional differences of Krit1A and Krit1B isoforms: a framework for understanding CCM pathogenesis. IX Convegno FISV (Federazione Italiana Scienze della Vita). Riva del Garda (TN), 26-29 Settembre 2007 67
KRIT1, a disease gene responsible for cerebral cavernous malformations (CCM), is involved in cell defences against oxidative stress. 60
Setting up of a yeast based system for the production of plant derived antioxidants 59
Ras GTPases Are Both Regulators and Effectors of Redox Agents 55
null 43
Totale 7.995
Categoria #
all - tutte 24.539
article - articoli 0
book - libri 0
conference - conferenze 13.773
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.312


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021425 0 0 0 0 70 29 47 33 76 54 54 62
2021/2022750 27 20 22 38 33 24 48 57 9 62 219 191
2022/20231.173 145 125 52 162 79 260 78 79 104 17 54 18
2023/2024491 49 94 28 25 43 79 21 27 8 24 24 69
2024/20251.367 20 75 60 139 329 106 20 42 209 73 126 168
2025/20261.051 264 97 148 337 205 0 0 0 0 0 0 0
Totale 7.995