DEFILIPPI, Paola
 Distribuzione geografica
Continente #
NA - Nord America 5.873
EU - Europa 4.059
AS - Asia 2.285
AF - Africa 106
SA - Sud America 43
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 5
Totale 12.394
Nazione #
US - Stati Uniti d'America 5.749
CN - Cina 1.428
IT - Italia 1.036
SE - Svezia 469
IE - Irlanda 426
DE - Germania 423
FR - Francia 316
UA - Ucraina 296
GB - Regno Unito 241
FI - Finlandia 235
KR - Corea 231
SG - Singapore 218
AT - Austria 197
CA - Canada 121
PL - Polonia 117
JP - Giappone 115
VN - Vietnam 100
DK - Danimarca 99
SN - Senegal 90
HK - Hong Kong 55
IN - India 52
BE - Belgio 42
CH - Svizzera 37
NL - Olanda 32
RU - Federazione Russa 31
BR - Brasile 27
TW - Taiwan 25
AU - Australia 20
ES - Italia 17
SA - Arabia Saudita 13
CL - Cile 10
PT - Portogallo 10
IR - Iran 9
GR - Grecia 8
JO - Giordania 6
MY - Malesia 6
RO - Romania 6
TR - Turchia 6
EU - Europa 5
AR - Argentina 4
CZ - Repubblica Ceca 4
HU - Ungheria 4
NG - Nigeria 4
NO - Norvegia 4
PK - Pakistan 4
TH - Thailandia 4
IL - Israele 3
MA - Marocco 3
MX - Messico 3
NZ - Nuova Zelanda 3
UZ - Uzbekistan 3
DZ - Algeria 2
EE - Estonia 2
EG - Egitto 2
HR - Croazia 2
KE - Kenya 2
NP - Nepal 2
BG - Bulgaria 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CO - Colombia 1
CY - Cipro 1
ET - Etiopia 1
ID - Indonesia 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
PE - Perù 1
PH - Filippine 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 12.394
Città #
Chandler 896
Beijing 608
Fairfield 475
Dublin 423
Ann Arbor 316
Houston 290
Ashburn 270
Torino 253
Woodbridge 237
Wilmington 219
Vienna 192
Seattle 190
Jacksonville 160
Cambridge 143
Turin 142
Villeurbanne 142
Medford 140
Singapore 139
Nyköping 137
Princeton 125
Pisa 115
Dearborn 111
Warsaw 109
Milan 106
Fremont 94
Shanghai 94
Boardman 67
Toronto 64
New York 59
Boston 55
Hangzhou 55
Nanjing 50
Dong Ket 49
Guangzhou 49
Redwood City 45
Brussels 37
Falls Church 35
San Diego 32
Verona 32
Seongnam 27
Hong Kong 26
Lachine 25
Helsinki 23
Seoul 22
Wuhan 22
Hefei 21
Munich 21
Norwalk 21
Phoenix 21
Tokyo 21
Fuzhou 20
Los Angeles 17
Xian 17
Halle 16
Shenyang 16
Bern 15
Düsseldorf 15
Rome 15
Taipei 14
Washington 14
Zhengzhou 14
London 13
Hebei 12
Kunming 12
Silver Spring 12
Chengdu 11
Chicago 11
Chongqing 11
Jinan 11
Santa Clara 11
Upper Marlboro 11
Shenzhen 10
Trieste 10
Brignano Gera d'Adda 9
Changsha 9
Frankfurt am Main 9
Kharkiv 9
Mountain View 9
Nanchang 9
Nuremberg 9
Santiago 9
Shijiazhuang 9
Tappahannock 9
Edinburgh 8
Amsterdam 7
Bengaluru 7
Copenhagen 7
Gangnam-gu 7
Guiyang 7
Madrid 7
Perugia 7
Philadelphia 7
Xi'an 7
Amman 6
Chuocho 6
Montpellier 6
Montréal 6
Pune 6
Tianjin 6
Berlin 5
Totale 7.515
Nome #
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts 724
Integrin signalling adaptors: not only figurants in the cancer story 534
β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. 501
p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits 390
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries 267
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis 266
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 243
Modeling ErbB2-p130Cas interaction to design new potential anticancer agents. 229
Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells 193
Cas proteins: dodgy scaffolding in breast cancer. 191
p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy 187
p130Cas promotes invasiveness of three dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1 185
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. 182
Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion 181
New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia 169
Histone arginine methylation in cocaine action in the nucleus accumbens 166
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. 162
Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome. 158
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma 157
p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. 155
p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells 149
The p140Cap adaptor protein as a molecular hub to block cancer aggressiveness 145
p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF 137
Synaptic interactome mining reveals p140cap as a new hub for PSD proteins involved in psychiatric and neurological disorders 135
Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation. 134
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3 132
Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase 131
The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy 130
p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors. 124
Dissecting the Shared and Context-Dependent Pathways Mediated by the p140Cap Adaptor Protein in Cancer and in Neurons 114
{beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation 113
Actin cytoskeleton organization in response to integrin-mediated adhesion. 110
Integrins and Signal Transduction 109
The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression 104
Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties 103
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression 102
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration 99
Association of the dystroglycan complex isolated from bovine brain synaptosomes with proteins involved in signal transduction. 96
Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation 96
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase. 95
P140Cap and P130Cas Adaptor Proteins as Molecular Hubs in Cell Migration and Invasion 93
The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. 90
p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity 89
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 89
p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis 88
Alpha 6.beta 1 integrin (laminin receptor) is down-regulated by tumor necrosis factor alpha and interleukin-1 beta in human endothelial cells. 87
STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity. 86
Antiviral activity of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 84
Defining the role of the adaptor protein p130Cas in mammary normal and cancer stem/progenitor cells 84
Tumor necrosis factor alpha and interferon gamma modulate the expression of the vitronectin receptor (integrin beta 3) in human endothelial cells. 83
Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers 81
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex 80
p130Cas is an essential transducer element in ErbB2 transformation 80
Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cells. 76
Ihibition of beta 1 integrin and IL-3R beta common subunit interaction hinders tumor angiogenesis 76
The N-terminal domain of the adaptor protein p140Cap interacts with Tiam1 and controls Tiam1/Rac1 axis 76
Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses 76
Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis. 75
p130Cas: a versatile scaffold in signaling networks 75
p130Cas and p140Cap the bad and the good guys in breast cancer cell progression to an invasive phenotype 74
Actin cytoskeleton polymerization in Dbl-transformed NIH3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins 73
Up-regulation of the integrin alpha 1/beta 1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin. 72
Expression of receptors for extracellular matrix proteins in human endothelial cells. 72
GENOTOXIC TESTING"Regolazione dell'espressione della proteina p130Cas nei tumori" 71
p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation 71
Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology. 71
Regulation of adhesion receptors expression in endothelial cells. 70
P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading 70
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene–dependent breast tumorigenesis 69
p140Cap and Citron‐N: a "spiny" Cooperative Relationship 69
p130Cas Alters the Differentiation Potential of Mammary Luminal Progenitors by Deregulating C-Kit Activity. 69
Induction of intracellular signals through binding of adhesive molecules. Activation of p125FAK tyrosine phosphorylation. 68
Integrin-mediated adhesion of endothelial cells induces JAK2 and STAT5A activation: role in the control of c-fos gene expression. 66
Inhibition of beta1 integrin and IL-3Rbeta common subunit interaction hinders tumour angiogenesis 66
p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells 65
Integrin-mediated signal transduction in human endothelial cells: analysis of tyrosine phosphorylation events. 63
The essence of integrin signal transduction. Assembly od dynamic scaffolds and cross-talk with other receptors 63
Author Correction: Modeling ErbB2-p130Cas interaction to design new potential anticancer agents (Scientific Reports, (2019), 9, 1, (3089), 10.1038/s41598-019-39510-w) 63
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis 62
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis. 62
ASSOCIATION OF DYSTROGLYCAN-COMPLEX ISOLATED FROM BOVINE BRAIN SYNAPTOSOMES WITH PROTEINS INVOLVED IN SIGNAL TRANSDUCTION 61
p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation. 61
Antiviral activity towards VSV and Mengo virus of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 59
Role of tyrosine phosphorylation in matrix-induced neurite outgrowth in human neuroblastoma cells. 59
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression 59
SNAP-25 regulates spine formation through postsynaptic binding to p140Cap 58
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis 58
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach 57
p130Cas/ BCAR1 and p140Cap/ SRCIN1 Adaptors: The Yin Yang in Breast Cancer? 57
Modulation of extracellular matrix receptors (integrins) on human endothelial cells by cytokines. 56
Full-length sequence and expression of the 42 kDa 2-5A synthetase induced by human interferon. 55
Distinct involvement of cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells. 55
Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. 55
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity 54
Role of azithromycin in antiviral treatment: enhancement of interferon-dependent antiviral pathways and mitigation of inflammation may rely on inhibition of the MAPK cascade? 54
Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. 53
Molecular cloning of two genes induced by alpha-interferon in human cells. 52
Integrin synthesis and utilization in cultured human osteoblasts. 52
Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly. Involvement of protein kinase C, Rho GTPase, and tyrosine phosphorylation 52
The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization 51
Totale 11.713
Categoria #
all - tutte 35.721
article - articoli 0
book - libri 0
conference - conferenze 955
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.676


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.635 0 64 131 157 129 224 208 135 237 142 103 105
2020/20211.599 91 154 169 82 230 87 116 71 178 138 87 196
2021/20221.744 110 87 93 162 96 70 164 100 60 136 308 358
2022/20232.537 243 213 88 301 212 561 165 166 294 60 137 97
2023/20241.472 121 243 93 100 121 191 83 115 40 103 107 155
2024/2025227 103 124 0 0 0 0 0 0 0 0 0 0
Totale 12.747