DEFILIPPI, Paola
 Distribuzione geografica
Continente #
NA - Nord America 6.505
EU - Europa 4.183
AS - Asia 2.785
AF - Africa 106
SA - Sud America 46
OC - Oceania 25
Continente sconosciuto - Info sul continente non disponibili 5
Totale 13.655
Nazione #
US - Stati Uniti d'America 6.370
CN - Cina 1.544
IT - Italia 1.099
SG - Singapore 524
SE - Svezia 469
DE - Germania 439
IE - Irlanda 427
FR - Francia 321
UA - Ucraina 296
GB - Regno Unito 251
FI - Finlandia 247
KR - Corea 233
AT - Austria 199
CA - Canada 130
JP - Giappone 119
PL - Polonia 117
DK - Danimarca 100
VN - Vietnam 100
SN - Senegal 90
HK - Hong Kong 62
IN - India 58
ID - Indonesia 52
BE - Belgio 43
CH - Svizzera 39
NL - Olanda 34
RU - Federazione Russa 31
BR - Brasile 29
TW - Taiwan 27
ES - Italia 23
AU - Australia 21
SA - Arabia Saudita 13
PT - Portogallo 11
CL - Cile 10
IR - Iran 9
GR - Grecia 8
MY - Malesia 7
TR - Turchia 7
JO - Giordania 6
RO - Romania 6
EU - Europa 5
MX - Messico 5
NO - Norvegia 5
PK - Pakistan 5
AR - Argentina 4
CZ - Repubblica Ceca 4
HU - Ungheria 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
TH - Thailandia 4
BD - Bangladesh 3
IL - Israele 3
MA - Marocco 3
UZ - Uzbekistan 3
DZ - Algeria 2
EE - Estonia 2
EG - Egitto 2
HR - Croazia 2
KE - Kenya 2
NP - Nepal 2
PE - Perù 2
BG - Bulgaria 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CO - Colombia 1
CY - Cipro 1
ET - Etiopia 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LT - Lituania 1
PH - Filippine 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 13.655
Città #
Chandler 896
Beijing 612
Fairfield 475
Singapore 433
Dublin 424
Santa Clara 324
Ann Arbor 316
Houston 290
Ashburn 274
Torino 253
Woodbridge 237
Wilmington 219
Vienna 192
Seattle 190
Turin 174
Jacksonville 160
Cambridge 143
Villeurbanne 142
Medford 140
Nyköping 137
Princeton 125
Pisa 115
Columbus 111
Dearborn 111
Milan 110
Warsaw 109
Shanghai 103
Fremont 94
Boardman 68
Toronto 67
New York 59
Guangzhou 56
Hangzhou 56
Boston 55
Jakarta 52
Nanjing 50
Dong Ket 49
Redwood City 45
Brussels 38
Falls Church 35
Helsinki 32
San Diego 32
Verona 32
Munich 29
Hong Kong 28
Seongnam 27
Lachine 25
Tokyo 25
Wuhan 23
Seoul 22
Hefei 21
Los Angeles 21
Norwalk 21
Phoenix 21
Fuzhou 20
Shenyang 17
Xian 17
Halle 16
London 16
Bern 15
Düsseldorf 15
Jinan 15
Rome 15
Zhengzhou 15
Kunming 14
Taipei 14
Washington 14
Frankfurt am Main 12
Hebei 12
Silver Spring 12
Changsha 11
Chengdu 11
Chicago 11
Chongqing 11
Upper Marlboro 11
San Jose 10
Shenzhen 10
Trieste 10
Bengaluru 9
Brignano Gera d'Adda 9
Guiyang 9
Kharkiv 9
Montreal 9
Mountain View 9
Nanchang 9
Nuremberg 9
Santiago 9
Shijiazhuang 9
Tappahannock 9
Amsterdam 8
Copenhagen 8
Edinburgh 8
Gangnam-gu 7
Madrid 7
Paris 7
Perugia 7
Philadelphia 7
Qingdao 7
Xi'an 7
Amman 6
Totale 8.400
Nome #
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts 841
Integrin signalling adaptors: not only figurants in the cancer story 572
β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. 532
p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits 399
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries 280
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis 277
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 252
Modeling ErbB2-p130Cas interaction to design new potential anticancer agents. 245
Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells 207
Cas proteins: dodgy scaffolding in breast cancer. 200
p130Cas promotes invasiveness of three dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1 199
p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy 197
Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion 192
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. 188
New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia 179
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. 178
Histone arginine methylation in cocaine action in the nucleus accumbens 170
Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome. 167
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma 167
p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. 166
p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells 160
The p140Cap adaptor protein as a molecular hub to block cancer aggressiveness 153
Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation. 152
Synaptic interactome mining reveals p140cap as a new hub for PSD proteins involved in psychiatric and neurological disorders 151
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3 149
The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy 148
p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF 146
Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase 143
p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors. 127
Actin cytoskeleton organization in response to integrin-mediated adhesion. 120
{beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation 120
Integrins and Signal Transduction 120
The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression 120
Dissecting the Shared and Context-Dependent Pathways Mediated by the p140Cap Adaptor Protein in Cancer and in Neurons 119
Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties 118
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase. 113
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression 107
P140Cap and P130Cas Adaptor Proteins as Molecular Hubs in Cell Migration and Invasion 104
Association of the dystroglycan complex isolated from bovine brain synaptosomes with proteins involved in signal transduction. 102
The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. 101
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration 101
Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation 101
p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity 100
p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis 100
Alpha 6.beta 1 integrin (laminin receptor) is down-regulated by tumor necrosis factor alpha and interleukin-1 beta in human endothelial cells. 97
Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers 96
Defining the role of the adaptor protein p130Cas in mammary normal and cancer stem/progenitor cells 93
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 93
STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity. 90
Antiviral activity of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 89
p130Cas is an essential transducer element in ErbB2 transformation 89
p130Cas: a versatile scaffold in signaling networks 89
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex 88
Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses 88
Tumor necrosis factor alpha and interferon gamma modulate the expression of the vitronectin receptor (integrin beta 3) in human endothelial cells. 87
The N-terminal domain of the adaptor protein p140Cap interacts with Tiam1 and controls Tiam1/Rac1 axis 87
Ihibition of beta 1 integrin and IL-3R beta common subunit interaction hinders tumor angiogenesis 86
Actin cytoskeleton polymerization in Dbl-transformed NIH3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins 85
Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis. 84
p130Cas and p140Cap the bad and the good guys in breast cancer cell progression to an invasive phenotype 84
p130Cas Alters the Differentiation Potential of Mammary Luminal Progenitors by Deregulating C-Kit Activity. 82
Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cells. 81
p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation 80
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis 80
GENOTOXIC TESTING"Regolazione dell'espressione della proteina p130Cas nei tumori" 79
p140Cap and Citron‐N: a "spiny" Cooperative Relationship 79
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis. 79
P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading 78
Author Correction: Modeling ErbB2-p130Cas interaction to design new potential anticancer agents (Scientific Reports, (2019), 9, 1, (3089), 10.1038/s41598-019-39510-w) 78
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene–dependent breast tumorigenesis 77
Integrin-mediated adhesion of endothelial cells induces JAK2 and STAT5A activation: role in the control of c-fos gene expression. 76
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression 75
Up-regulation of the integrin alpha 1/beta 1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin. 74
Expression of receptors for extracellular matrix proteins in human endothelial cells. 74
p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells 74
Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology. 74
Regulation of adhesion receptors expression in endothelial cells. 73
Inhibition of beta1 integrin and IL-3Rbeta common subunit interaction hinders tumour angiogenesis 72
Induction of intracellular signals through binding of adhesive molecules. Activation of p125FAK tyrosine phosphorylation. 71
p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation. 70
The essence of integrin signal transduction. Assembly od dynamic scaffolds and cross-talk with other receptors 69
ASSOCIATION OF DYSTROGLYCAN-COMPLEX ISOLATED FROM BOVINE BRAIN SYNAPTOSOMES WITH PROTEINS INVOLVED IN SIGNAL TRANSDUCTION 68
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis 68
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach 67
p130Cas/ BCAR1 and p140Cap/ SRCIN1 Adaptors: The Yin Yang in Breast Cancer? 67
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity 66
Integrin-mediated signal transduction in human endothelial cells: analysis of tyrosine phosphorylation events. 65
Antiviral activity towards VSV and Mengo virus of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 64
SNAP-25 regulates spine formation through postsynaptic binding to p140Cap 64
Role of azithromycin in antiviral treatment: enhancement of interferon-dependent antiviral pathways and mitigation of inflammation may rely on inhibition of the MAPK cascade? 64
Role of tyrosine phosphorylation in matrix-induced neurite outgrowth in human neuroblastoma cells. 61
Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells 61
Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. 60
Modulation of extracellular matrix receptors (integrins) on human endothelial cells by cytokines. 59
Distinct involvement of cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells. 59
Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues. 59
The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization 58
Full-length sequence and expression of the 42 kDa 2-5A synthetase induced by human interferon. 57
Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. 57
Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly. Involvement of protein kinase C, Rho GTPase, and tyrosine phosphorylation 57
Totale 12.784
Categoria #
all - tutte 40.529
article - articoli 0
book - libri 0
conference - conferenze 1.075
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.604


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.154 0 0 0 0 0 224 208 135 237 142 103 105
2020/20211.599 91 154 169 82 230 87 116 71 178 138 87 196
2021/20221.744 110 87 93 162 96 70 164 100 60 136 308 358
2022/20232.537 243 213 88 301 212 561 165 166 294 60 137 97
2023/20241.472 121 243 93 100 121 191 83 115 40 103 107 155
2024/20251.489 103 213 140 277 674 82 0 0 0 0 0 0
Totale 14.009