DEFILIPPI, Paola
 Distribuzione geografica
Continente #
NA - Nord America 5.787
EU - Europa 3.953
AS - Asia 1.971
AF - Africa 105
SA - Sud America 37
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 5
Totale 11.881
Nazione #
US - Stati Uniti d'America 5.664
CN - Cina 1.328
IT - Italia 991
SE - Svezia 466
IE - Irlanda 424
DE - Germania 400
FR - Francia 309
UA - Ucraina 287
GB - Regno Unito 237
FI - Finlandia 226
KR - Corea 223
AT - Austria 197
CA - Canada 120
PL - Polonia 117
JP - Giappone 113
VN - Vietnam 100
DK - Danimarca 99
SN - Senegal 90
IN - India 45
BE - Belgio 42
SG - Singapore 41
HK - Hong Kong 40
CH - Svizzera 37
RU - Federazione Russa 31
NL - Olanda 30
TW - Taiwan 25
BR - Brasile 22
AU - Australia 20
ES - Italia 17
SA - Arabia Saudita 13
CL - Cile 10
PT - Portogallo 10
IR - Iran 9
GR - Grecia 8
MY - Malesia 6
EU - Europa 5
RO - Romania 5
AR - Argentina 4
HU - Ungheria 4
JO - Giordania 4
NG - Nigeria 4
NO - Norvegia 4
PK - Pakistan 4
TH - Thailandia 4
CZ - Repubblica Ceca 3
IL - Israele 3
MA - Marocco 3
MX - Messico 3
NZ - Nuova Zelanda 3
TR - Turchia 3
UZ - Uzbekistan 3
DZ - Algeria 2
EE - Estonia 2
EG - Egitto 2
HR - Croazia 2
KE - Kenya 2
NP - Nepal 2
BG - Bulgaria 1
BY - Bielorussia 1
CO - Colombia 1
CY - Cipro 1
ET - Etiopia 1
ID - Indonesia 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
PH - Filippine 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 11.881
Città #
Chandler 896
Beijing 608
Fairfield 475
Dublin 421
Ann Arbor 316
Houston 290
Ashburn 269
Torino 253
Woodbridge 237
Wilmington 219
Vienna 192
Seattle 190
Jacksonville 160
Cambridge 143
Villeurbanne 142
Medford 140
Nyköping 137
Princeton 125
Turin 120
Pisa 115
Dearborn 111
Warsaw 109
Milan 99
Fremont 94
Shanghai 85
Toronto 64
Boardman 62
New York 59
Hangzhou 52
Boston 50
Dong Ket 49
Guangzhou 47
Redwood City 45
Brussels 37
Falls Church 35
Nanjing 35
San Diego 32
Verona 32
Seongnam 27
Lachine 25
Seoul 22
Hefei 21
Norwalk 21
Fuzhou 20
Phoenix 20
Munich 19
Tokyo 19
Xian 17
Bern 15
Düsseldorf 15
Shenyang 15
Wuhan 15
Helsinki 14
Taipei 14
Washington 14
Zhengzhou 14
Hong Kong 13
London 13
Halle 12
Hebei 12
Kunming 12
Los Angeles 12
Rome 12
Chicago 11
Chongqing 11
Jinan 11
Upper Marlboro 11
Silver Spring 10
Singapore 10
Trieste 10
Brignano Gera d'Adda 9
Chengdu 9
Mountain View 9
Nanchang 9
Santiago 9
Shenzhen 9
Tappahannock 9
Edinburgh 8
Amsterdam 7
Bengaluru 7
Changsha 7
Copenhagen 7
Guiyang 7
Madrid 7
Perugia 7
Philadelphia 7
Chuocho 6
Frankfurt am Main 6
Montpellier 6
Montréal 6
Pune 6
Tianjin 6
Berlin 5
Central 5
Dallas 5
Darmstadt 5
Des Moines 5
Evanston 5
Kolkata 5
Muenster 5
Totale 7.235
Nome #
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts 593
Integrin signalling adaptors: not only figurants in the cancer story 521
β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. 484
p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits 389
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis 263
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries 262
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 240
Modeling ErbB2-p130Cas interaction to design new potential anticancer agents. 229
Cas proteins: dodgy scaffolding in breast cancer. 191
Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells 186
p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy 186
Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion 180
p130Cas promotes invasiveness of three dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1 179
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. 172
New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia 163
Histone arginine methylation in cocaine action in the nucleus accumbens 162
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. 157
Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome. 155
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma 151
p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. 150
p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells 147
The p140Cap adaptor protein as a molecular hub to block cancer aggressiveness 140
p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF 136
Synaptic interactome mining reveals p140cap as a new hub for PSD proteins involved in psychiatric and neurological disorders 133
Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation. 131
Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase 130
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3 124
p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors. 117
{beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation 113
Dissecting the Shared and Context-Dependent Pathways Mediated by the p140Cap Adaptor Protein in Cancer and in Neurons 111
The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy 111
Integrins and Signal Transduction 107
Actin cytoskeleton organization in response to integrin-mediated adhesion. 104
The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression 102
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression 100
Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties 100
Association of the dystroglycan complex isolated from bovine brain synaptosomes with proteins involved in signal transduction. 96
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration 96
Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation 95
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase. 92
P140Cap and P130Cas Adaptor Proteins as Molecular Hubs in Cell Migration and Invasion 91
p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity 88
Alpha 6.beta 1 integrin (laminin receptor) is down-regulated by tumor necrosis factor alpha and interleukin-1 beta in human endothelial cells. 85
STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity. 85
p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis 85
The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. 84
Antiviral activity of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 83
Defining the role of the adaptor protein p130Cas in mammary normal and cancer stem/progenitor cells 82
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 82
Tumor necrosis factor alpha and interferon gamma modulate the expression of the vitronectin receptor (integrin beta 3) in human endothelial cells. 81
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex 79
Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers 77
p130Cas is an essential transducer element in ErbB2 transformation 76
Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses 76
Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cells. 75
p130Cas: a versatile scaffold in signaling networks 74
Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis. 73
p130Cas and p140Cap the bad and the good guys in breast cancer cell progression to an invasive phenotype 73
Up-regulation of the integrin alpha 1/beta 1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin. 71
Expression of receptors for extracellular matrix proteins in human endothelial cells. 71
p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation 71
Ihibition of beta 1 integrin and IL-3R beta common subunit interaction hinders tumor angiogenesis 71
Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology. 70
Regulation of adhesion receptors expression in endothelial cells. 69
P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading 69
Actin cytoskeleton polymerization in Dbl-transformed NIH3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins 69
GENOTOXIC TESTING"Regolazione dell'espressione della proteina p130Cas nei tumori" 68
p140Cap and Citron‐N: a "spiny" Cooperative Relationship 68
Induction of intracellular signals through binding of adhesive molecules. Activation of p125FAK tyrosine phosphorylation. 67
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene–dependent breast tumorigenesis 66
Integrin-mediated adhesion of endothelial cells induces JAK2 and STAT5A activation: role in the control of c-fos gene expression. 65
Inhibition of beta1 integrin and IL-3Rbeta common subunit interaction hinders tumour angiogenesis 65
The N-terminal domain of the adaptor protein p140Cap interacts with Tiam1 and controls Tiam1/Rac1 axis 65
p130Cas Alters the Differentiation Potential of Mammary Luminal Progenitors by Deregulating C-Kit Activity. 65
p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells 64
Integrin-mediated signal transduction in human endothelial cells: analysis of tyrosine phosphorylation events. 62
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis. 62
The essence of integrin signal transduction. Assembly od dynamic scaffolds and cross-talk with other receptors 61
ASSOCIATION OF DYSTROGLYCAN-COMPLEX ISOLATED FROM BOVINE BRAIN SYNAPTOSOMES WITH PROTEINS INVOLVED IN SIGNAL TRANSDUCTION 60
Author Correction: Modeling ErbB2-p130Cas interaction to design new potential anticancer agents (Scientific Reports, (2019), 9, 1, (3089), 10.1038/s41598-019-39510-w) 60
Antiviral activity towards VSV and Mengo virus of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 58
Role of tyrosine phosphorylation in matrix-induced neurite outgrowth in human neuroblastoma cells. 57
p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation. 57
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis 56
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression 56
Modulation of extracellular matrix receptors (integrins) on human endothelial cells by cytokines. 55
Full-length sequence and expression of the 42 kDa 2-5A synthetase induced by human interferon. 54
Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. 54
SNAP-25 regulates spine formation through postsynaptic binding to p140Cap 54
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis 54
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach 53
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity 53
Distinct involvement of cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells. 52
Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. 52
Molecular cloning of two genes induced by alpha-interferon in human cells. 51
Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly. Involvement of protein kinase C, Rho GTPase, and tyrosine phosphorylation 51
Role of azithromycin in antiviral treatment: enhancement of interferon-dependent antiviral pathways and mitigation of inflammation may rely on inhibition of the MAPK cascade? 51
Integrin synthesis and utilization in cultured human osteoblasts. 50
The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization 50
Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells 50
Totale 11.274
Categoria #
all - tutte 31.323
article - articoli 0
book - libri 0
conference - conferenze 836
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 32.159


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019525 0 0 0 0 0 0 0 0 0 115 281 129
2019/20201.733 98 64 131 157 129 224 208 135 237 142 103 105
2020/20211.599 91 154 169 82 230 87 116 71 178 138 87 196
2021/20221.744 110 87 93 162 96 70 164 100 60 136 308 358
2022/20232.537 243 213 88 301 212 561 165 166 294 60 137 97
2023/20241.185 121 243 93 100 121 191 83 115 40 78 0 0
Totale 12.233