DEFILIPPI, Paola
 Distribuzione geografica
Continente #
NA - Nord America 6.851
EU - Europa 4.613
AS - Asia 3.730
SA - Sud America 341
AF - Africa 120
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.686
Nazione #
US - Stati Uniti d'America 6.699
CN - Cina 1.779
IT - Italia 1.197
SG - Singapore 1.066
DE - Germania 570
SE - Svezia 472
IE - Irlanda 428
FR - Francia 333
FI - Finlandia 318
UA - Ucraina 297
BR - Brasile 293
GB - Regno Unito 263
KR - Corea 238
AT - Austria 227
JP - Giappone 152
CA - Canada 135
PL - Polonia 119
VN - Vietnam 110
HK - Hong Kong 108
DK - Danimarca 101
SN - Senegal 90
IN - India 78
NL - Olanda 60
ID - Indonesia 54
RU - Federazione Russa 53
BE - Belgio 44
CH - Svizzera 40
ES - Italia 33
TW - Taiwan 31
AU - Australia 22
SA - Arabia Saudita 16
AR - Argentina 15
CL - Cile 15
MX - Messico 14
PT - Portogallo 14
TR - Turchia 14
IR - Iran 13
PK - Pakistan 10
BD - Bangladesh 8
GR - Grecia 8
MY - Malesia 8
JO - Giordania 7
MA - Marocco 7
VE - Venezuela 7
IL - Israele 6
RO - Romania 6
CZ - Repubblica Ceca 5
EG - Egitto 5
EU - Europa 5
KE - Kenya 5
MO - Macao, regione amministrativa speciale della Cina 5
NO - Norvegia 5
TH - Thailandia 5
UZ - Uzbekistan 5
ZA - Sudafrica 5
HU - Ungheria 4
IQ - Iraq 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
CO - Colombia 3
EC - Ecuador 3
EE - Estonia 3
HR - Croazia 3
PE - Perù 3
AZ - Azerbaigian 2
CY - Cipro 2
DZ - Algeria 2
JM - Giamaica 2
KZ - Kazakistan 2
LK - Sri Lanka 2
LT - Lituania 2
NP - Nepal 2
RS - Serbia 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BG - Bulgaria 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
ET - Etiopia 1
IS - Islanda 1
LB - Libano 1
LV - Lettonia 1
PA - Panama 1
PH - Filippine 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
UY - Uruguay 1
Totale 15.686
Città #
Chandler 896
Beijing 637
Singapore 558
Fairfield 475
Dublin 425
Santa Clara 364
Ann Arbor 318
Ashburn 297
Houston 292
Torino 253
Woodbridge 237
Wilmington 219
Turin 216
Vienna 208
Seattle 192
Jacksonville 161
Cambridge 143
Villeurbanne 142
Medford 140
Nyköping 137
Columbus 126
Princeton 125
Shanghai 123
Munich 122
Milan 121
Pisa 115
Dearborn 111
Warsaw 111
Fremont 94
Boardman 75
Hong Kong 73
Guangzhou 69
Toronto 67
New York 65
Boston 64
Hangzhou 59
Turku 59
Jakarta 52
Nanjing 50
Dong Ket 49
Redwood City 45
Helsinki 43
Brussels 39
Hefei 37
Nuremberg 37
Falls Church 35
San Diego 32
Verona 32
Los Angeles 31
Tokyo 31
Phoenix 27
Seongnam 27
São Paulo 27
Lachine 25
Wuhan 23
Seoul 22
Shenyang 22
London 21
Norwalk 21
Fuzhou 20
Silver Spring 20
Zhengzhou 19
Jinan 18
Düsseldorf 17
The Dalles 17
Xian 17
Halle 16
Bern 15
Chengdu 15
Kunming 15
Rome 15
Changsha 14
Chicago 14
Taipei 14
Washington 14
Paris 13
San Francisco 13
San Jose 13
Chongqing 12
Dallas 12
Frankfurt am Main 12
Hebei 12
Shenzhen 12
Bengaluru 11
Guiyang 11
North Bergen 11
Trieste 11
Upper Marlboro 11
Amsterdam 10
Philadelphia 10
Qingdao 10
Rio de Janeiro 10
Shijiazhuang 10
Brignano Gera d'Adda 9
Kharkiv 9
Montreal 9
Moscow 9
Mountain View 9
Nagoya 9
Nanchang 9
Totale 9.144
Nome #
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts 1.086
Integrin signalling adaptors: not only figurants in the cancer story 637
β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. 557
p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits 415
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries 300
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis 298
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 271
Modeling ErbB2-p130Cas interaction to design new potential anticancer agents. 270
Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells 231
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3 231
p130Cas promotes invasiveness of three dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1 228
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. 221
Cas proteins: dodgy scaffolding in breast cancer. 212
p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy 210
Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion 205
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. 194
New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia 193
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma 192
p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. 191
Histone arginine methylation in cocaine action in the nucleus accumbens 186
The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy 182
Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome. 178
p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells 174
The p140Cap adaptor protein as a molecular hub to block cancer aggressiveness 171
Synaptic interactome mining reveals p140cap as a new hub for PSD proteins involved in psychiatric and neurological disorders 169
Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation. 166
Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase 165
p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF 162
Integrins and Signal Transduction 143
p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors. 142
Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties 141
Dissecting the Shared and Context-Dependent Pathways Mediated by the p140Cap Adaptor Protein in Cancer and in Neurons 140
The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression 133
Actin cytoskeleton organization in response to integrin-mediated adhesion. 130
{beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation 129
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase. 127
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression 126
P140Cap and P130Cas Adaptor Proteins as Molecular Hubs in Cell Migration and Invasion 122
p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity 119
The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. 117
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration 115
p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis 114
Association of the dystroglycan complex isolated from bovine brain synaptosomes with proteins involved in signal transduction. 112
Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers 110
The N-terminal domain of the adaptor protein p140Cap interacts with Tiam1 and controls Tiam1/Rac1 axis 110
Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation 107
Defining the role of the adaptor protein p130Cas in mammary normal and cancer stem/progenitor cells 106
Alpha 6.beta 1 integrin (laminin receptor) is down-regulated by tumor necrosis factor alpha and interleukin-1 beta in human endothelial cells. 105
p130Cas is an essential transducer element in ErbB2 transformation 103
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 103
STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity. 101
Actin cytoskeleton polymerization in Dbl-transformed NIH3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins 101
Ihibition of beta 1 integrin and IL-3R beta common subunit interaction hinders tumor angiogenesis 100
p130Cas and p140Cap the bad and the good guys in breast cancer cell progression to an invasive phenotype 100
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression 100
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis. 98
Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses 98
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis 98
Antiviral activity of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 97
Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis. 97
p130Cas: a versatile scaffold in signaling networks 97
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex 96
p140Cap and Citron‐N: a "spiny" Cooperative Relationship 94
p130Cas Alters the Differentiation Potential of Mammary Luminal Progenitors by Deregulating C-Kit Activity. 94
Tumor necrosis factor alpha and interferon gamma modulate the expression of the vitronectin receptor (integrin beta 3) in human endothelial cells. 93
Author Correction: Modeling ErbB2-p130Cas interaction to design new potential anticancer agents (Scientific Reports, (2019), 9, 1, (3089), 10.1038/s41598-019-39510-w) 93
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene–dependent breast tumorigenesis 90
p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation 89
p130Cas/ BCAR1 and p140Cap/ SRCIN1 Adaptors: The Yin Yang in Breast Cancer? 89
Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cells. 88
GENOTOXIC TESTING"Regolazione dell'espressione della proteina p130Cas nei tumori" 88
P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading 88
Expression of receptors for extracellular matrix proteins in human endothelial cells. 87
Integrin-mediated adhesion of endothelial cells induces JAK2 and STAT5A activation: role in the control of c-fos gene expression. 84
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis 83
p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation. 83
p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response 82
ASSOCIATION OF DYSTROGLYCAN-COMPLEX ISOLATED FROM BOVINE BRAIN SYNAPTOSOMES WITH PROTEINS INVOLVED IN SIGNAL TRANSDUCTION 82
Inhibition of beta1 integrin and IL-3Rbeta common subunit interaction hinders tumour angiogenesis 82
p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells 80
Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology. 80
Up-regulation of the integrin alpha 1/beta 1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin. 78
Regulation of adhesion receptors expression in endothelial cells. 76
The essence of integrin signal transduction. Assembly od dynamic scaffolds and cross-talk with other receptors 76
Induction of intracellular signals through binding of adhesive molecules. Activation of p125FAK tyrosine phosphorylation. 75
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach 75
Role of azithromycin in antiviral treatment: enhancement of interferon-dependent antiviral pathways and mitigation of inflammation may rely on inhibition of the MAPK cascade? 75
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity 74
p140Cap regulates the composition and localization of the NMDAR complex in synaptic lipid rafts 73
Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells 73
Distinct involvement of cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells. 72
Cholesterol and Its Derivatives: Multifaceted Players in Breast Cancer Progression 71
SNAP-25 regulates spine formation through postsynaptic binding to p140Cap 70
Integrin-mediated signal transduction in human endothelial cells: analysis of tyrosine phosphorylation events. 69
Antiviral activity towards VSV and Mengo virus of a chemically stabilized 2-5A analog upon microinjection into HeLa cells. 69
RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition 68
The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization 68
Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues. 68
Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. 66
p140Cap modulates the mevalonate pathway decreasing cell migration and enhancing drug sensitivity in breast cancer cells 65
Totale 14.542
Categoria #
all - tutte 49.098
article - articoli 0
book - libri 0
conference - conferenze 1.286
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.384


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.599 91 154 169 82 230 87 116 71 178 138 87 196
2021/20221.744 110 87 93 162 96 70 164 100 60 136 308 358
2022/20232.537 243 213 88 301 212 561 165 166 294 60 137 97
2023/20241.472 121 243 93 100 121 191 83 115 40 103 107 155
2024/20253.387 103 213 140 277 674 285 97 199 406 239 334 420
2025/2026139 139 0 0 0 0 0 0 0 0 0 0 0
Totale 16.046