CASTELLA, BARBARA
 Distribuzione geografica
Continente #
NA - Nord America 3.364
EU - Europa 1.779
AS - Asia 1.150
AF - Africa 47
OC - Oceania 18
Continente sconosciuto - Info sul continente non disponibili 12
SA - Sud America 6
Totale 6.376
Nazione #
US - Stati Uniti d'America 3.332
CN - Cina 589
IT - Italia 363
SG - Singapore 342
SE - Svezia 282
IE - Irlanda 214
AT - Austria 211
UA - Ucraina 139
FR - Francia 130
DE - Germania 114
FI - Finlandia 105
PL - Polonia 70
KR - Corea 54
VN - Vietnam 50
SN - Senegal 36
GB - Regno Unito 34
CA - Canada 29
NL - Olanda 29
IN - India 28
ID - Indonesia 20
AU - Australia 18
JP - Giappone 17
RU - Federazione Russa 17
BE - Belgio 15
UZ - Uzbekistan 15
HK - Hong Kong 14
BY - Bielorussia 12
ES - Italia 12
EU - Europa 11
GR - Grecia 10
TW - Taiwan 8
CH - Svizzera 4
DK - Danimarca 3
MX - Messico 3
PH - Filippine 3
RO - Romania 3
ZA - Sudafrica 3
AR - Argentina 2
CZ - Repubblica Ceca 2
EG - Egitto 2
IQ - Iraq 2
IR - Iran 2
LT - Lituania 2
LU - Lussemburgo 2
MU - Mauritius 2
NG - Nigeria 2
NO - Norvegia 2
SI - Slovenia 2
TR - Turchia 2
A1 - Anonimo 1
BR - Brasile 1
BW - Botswana 1
CO - Colombia 1
HU - Ungheria 1
IL - Israele 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
PE - Perù 1
PK - Pakistan 1
SA - Arabia Saudita 1
TG - Togo 1
UY - Uruguay 1
Totale 6.376
Città #
Chandler 443
Beijing 376
Santa Clara 269
Singapore 265
Dublin 213
Vienna 209
Ashburn 204
Fairfield 189
Ann Arbor 162
Houston 140
Jacksonville 121
Nyköping 110
Dearborn 102
Torino 99
Woodbridge 95
Wilmington 80
Seattle 73
Medford 71
Villeurbanne 67
Cambridge 66
Princeton 66
Warsaw 64
Fremont 61
Columbus 59
Pisa 54
San Mateo 49
Turin 38
Redwood City 35
Washington 29
Dong Ket 26
Guangzhou 26
Jakarta 20
New York 19
Nanjing 18
Phoenix 18
Boston 17
Toronto 16
Milan 15
Boardman 14
Mountain View 14
Shanghai 14
Brussels 13
Hefei 12
Munich 12
Düsseldorf 11
Chengdu 10
Helsinki 10
Hangzhou 9
Changsha 8
Ottawa 8
Rotterdam 8
San Diego 8
Tokyo 8
Central District 7
Los Angeles 7
Norwalk 7
Paris 7
Provo 7
New Haven 6
Nuremberg 6
Pune 6
San Jose 6
Taipei 6
Adelaide 5
Den Haag 5
Fuzhou 5
Jinan 5
Liverpool 5
Volpago Del Montello 5
Des Moines 4
Genoa 4
Hebei 4
Kunming 4
Nanchang 4
Piemonte 4
Rome 4
Tianjin 4
Bucharest 3
Catania 3
Changchun 3
Chennai 3
Dallas 3
Falls Church 3
Heidelberg 3
Johannesburg 3
Kharkiv 3
Limoges 3
Mexico City 3
Philadelphia 3
Silver Spring 3
Upper Marlboro 3
Varese 3
Xian 3
Zhengzhou 3
Abuja 2
Antwerpen 2
Appiano Gentile 2
Athens 2
Central 2
Cincinnati 2
Totale 4.333
Nome #
IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells 286
The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells 258
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells 229
Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors 229
Anergic bone marrow Vγ9Vδ2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma 204
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer 181
Zoledronic Acid Restores Doxorubicin Chemosensitivity and Immunogenic Cell Death in Multidrug-Resistant Human Cancer Cells 163
Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells 163
Humoral immune responses toward tumor-derived antigens in previously untreated patients with chronic lymphocytic leukemia 145
ABCA1, apoA-I, and BTN3A1: A Legitimate ménage à trois in dendritic cells 137
The Mevalonate Pathway and Downstream Signal Transducers As Therapeutic Targets to Overcome Multidrug Resistance in Chronic Lymphocytic Leukemia (CLL) 133
Identification of Novel Tumor-Associated Antigens in Chronic Lymphocytic Leukemia (CLL) by Serological Proteome Analysis (SERPA) 132
Vγ9Vδ2 T cells as strategic weapons to improve the potency of immune checkpoint blockade and immune interventions in human myeloma 123
Vγ9Vδ2 T Cells in the Bone Marrow of Myeloma Patients: A Paradigm of Microenvironment-Induced Immune Suppression 120
IDENTIFICATION BY SEROLOGICAL PROTEOME ANALYSIS (SERPA) OF TUMOR-ASSOCIATED ANTIGENS ELICITING ANTIBODY RESPONSES IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) 118
CyTOF®: A New Tool to Decipher the Immunomodulatory Activity of Daratumumab 118
Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition. 116
The Mevalonate Pathway As a Metabolic Target to Circumvent Multidrug-Resistance in Chronic Lymphocytic Leukemia Cells 114
The tryptophan metabolism in the immune dysregulation of multiple myeloma 111
Identification and functional characterization of tumor specific antibody responses in chronic lymphocytic leukemia 110
Role of PD-1/PD-L1 axis in the immune paresis of bone marrow Vγ9Vδ2 T cells in multiple myeloma 109
IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF ANTIBODY IMMUNE RESPONSES ELICITED BY SELF ANTIGENS IN CHRONIC LYMPHOCYTIC LEUKEMIA 107
Targeting the mevalonate pathway and downstream signaling pathways as a strategy to circumvent multidrug-resistance in CLL cells 105
IMPACT OF THE MEVALONATE PATHWAY AND HIF/PGP AXIS IN MODULATING MULTIDRUG-RESISTANCE IN UNMUTATED CLL CELLS 105
Serological Proteome Analysis (SERPA) as a tool for the identification of novel tumor antigens in chronic lymphocytic leukemia (CLL) 104
Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells 103
Accelerated activity of the mevalonate pathway supports the immune escape and multidrug-resistance phenotype of IGHV unmutated chronic lymphocytic leukemia cells 98
IGHV Unmutated Chronic Lymphocytic Leukemia (CLL) B Cells Are More Susceptible to Spontaneous Apoptosis Than Mutated CLL B Cells and Are Subject to the Anti-Apoptotic Effect of Environmental Signals 96
SEROLOGICAL PROTEOME ANALYSIS (SERPA) FOR THE IDENTIFICATION OF TUMOR-ASSOCIATED ANTIGENS ELICITING ANTIBODY-RESPONSES IN CHRONIC LYMPHOCYTIC LEUKEMIA 96
Immune Modulation by Zoledronic Acid in Human Myeloma: An Advantageous Cross Talk between V{gamma}9V{delta}2 T Cells, {alpha}{beta} CD8+ T Cells, Regulatory T Cells, and Dendritic Cells 95
Dendritic Cells Can Be Primed to Concurrently Activate Both Unconventional Gamma/delta and Conventional alpha/beta T Cells 95
Identification by serological proteome analysis (SERPA) of tumor-associated antigens eliciting antibody-responses in chronic lymphocytic leukemia 94
The bone marrow of myeloma patients is steadily inhabited by a normal-sized pool of functional regulatory T cells irrespective of the disease status. 92
Identification by serological proteome analysis (SERPA) of novel tumor associated antigens in chronic lymphocytic leukemia (CLL) 91
Regulatory T Cells (Tregs) Are Highly Preserved in Multiple Myeloma Patients and Can Dominate Effector Functions 88
Microvesicles released from multiple myeloma cells are equipped with ectoenzymes belonging to canonical and non-canonical adenosinergic pathways and produce adenosine from ATP and NAD. 88
Effector gammadelta T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma 87
Frequency and function of regulatory T cells (Tregs) are highly preserved in multiple myeloma 87
Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells. 87
Mechanisms of Vgamma9Vdelta2 T cell activation by soluble metabolites generated by the mevalonate pathway. 86
ROLE OF THE MEVALONATE PATHWAY IN THE IMMUNOMODULATORY ACTIVITY OF ZOLEDRONIC ACID 84
The CXCR4 downstream signaling pathways in chronic lymphocytic leukemia: a target to reverse microenvironment protection 84
Distribution of γδ T cells in patients with hematological malignancies 83
TARGETING THE CXCR4 DOWNSTREAM SIGNALLING PATHWAYS TO REVERSE MICROENVIRONMENT PROTECTION IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS 81
null 80
The Mevalonate Metabolic Pathway and the CXCL12/CXCR4 Axis Reciprocally Interact and Are Implicated in Fludarabine Resistance of Chronic Lymphocytic Leukemia Cells 79
Enhanced ability of dendritic cells to stimulate innate and adaptive immunity upon short-term incubation with zoledronic acid 77
Mitochondrial metabolism: Inducer or therapeutic target in tumor immune-resistance? 77
The association of dexamethasone + simvastatin to overcome environment-mediated chemoresistance of chronic lymphocytic leukemia (CLL) cells 76
SEROLOGICAL PROTEOME ANALYSIS (SERPA) FOR THEIDENTIFICATION OF NOVEL TUMOR-ASSOCIATED ANTIGENS INCHRONIC LYMPHOCYTIC LEUKEMIA 74
IGHV UNMUTATED CLL B CELLS ARE MORE PRONE TO SPONTANEOUS APOPTOSIS AND DEPEND FROM THE ANTI-APOPTOTIC EFFECT OF ENVIRONMENTAL SIGNALS 73
TARGETING HIF-1A AND ITS REGULATORY PATHWAYS AS A STRATEGY TO HAMPER LEUKEMIA-MICROENVIRONMENT INTERACTIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA 71
TARGETING HIF-1 AND ITS REGULATORY PATHWAYS AS A STRATEGY TO HAMPER TUMOR-MICROENVIRONMENT INTERACTIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA 71
Daratumumab with or without chemotherapy in relapsed and refractory acute lymphoblastic leukemia. A retrospective observational Campus Acute Lymphoblastic Leukemia study 71
Immunomodulatory and clinical effects of daratumumab in T-cell acute lymphoblastic leukaemia 67
Ectonucleotidase expression on human amnion epithelial cells: Adenosinergic pathways and dichotomic effects on immune effector cell populations 66
Vγ9Vδ2 T cell-based immunotherapy in hematological malignancies: from bench to bedside 49
Targeting mevalonate pathway down-regulates ABCB1, reversing chemoresistance and immunoresistance in human cancer cells. 47
Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity 46
The mevalonate pathway as a metabolic target to circumvent multidrug-resistance in chronic lymphocytic leukemia cells (CLL) 45
Molecular dynamics of targeting CD38 in multiple myeloma 40
Metabolic approaches to rescue antitumor Vγ9Vδ2 T-cell functions in myeloma 30
Preclinical efficacy of carfilzomib in BRAF-mutant colorectal cancer models 26
Totale 6.600
Categoria #
all - tutte 19.309
article - articoli 0
book - libri 0
conference - conferenze 9.352
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.661


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020453 0 0 0 0 0 0 111 52 61 94 66 69
2020/2021882 70 88 49 83 109 37 44 62 68 54 112 106
2021/2022926 36 17 12 79 27 20 140 49 26 110 263 147
2022/20231.179 119 120 30 119 106 283 64 78 126 31 61 42
2023/2024511 60 88 43 20 27 109 13 43 4 15 37 52
2024/2025801 11 61 76 122 464 64 3 0 0 0 0 0
Totale 6.600